Publications - last updated August, 2008

2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002

• Wang Y, Klemke RL. Phosphoblast: A computational tool for comparing phosphoprotein signatures among large datasets. Mol Cell Proteomics 2008; 7 (1):145-62 PubMed | CMC Update article.

2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002

• Goldfinger LE, Ptak C, Jeffery ED, Shabanowitz J, Han J, Haling JR, Sherman NE, Fox JW, Hunt DF, Ginsberg MH. An Experimentally Derived Database of Candidate Ras-Interacting Proteins. J Proteome Res 2007; 6 (5):1806-11 PubMed | CMC Update article.
• Mayhew MW, Jeffery ED, Sherman NE, Nelson K, Polefrone JM, Pratt SJ, Shabanowitz J, Parsons JT, Fox JW, Hunt DF, Horwitz AF. Identification of phosphorylation sites in betaPIX and PAK1. J Cell Sci 2007; 120 (Pt 22):3911-8 PubMed | CMC Update article.
• Prager GW, Feral CC, Kim C, Han J, Ginsberg MH. CD98hc (SLC3a2) interaction with the integrin beta subunit cytoplasmic domain mediates adhesive signaling. J Biol Chem 2007; 282 (33):24477-84 PubMed.
• Wang Y, Ding SJ, Wang W, Jacobs JM, Qian WJ, Moore RJ, Yang F, Camp DG, 2nd, Smith RD, Klemke RL. Profiling signaling polarity in chemotactic cells. Proc Natl Acad Sci U S A 2007; 104 (20):8328-33 PubMed | CMC Update article.
• Wang Y, Ding SJ, Wang W, Yang F, Jacobs JM, Camp D, 2nd, Smith RD, Klemke RL. Methods for pseudopodia purification and proteomic analysis. Sci STKE 2007; 2007 (400):pl4 PubMed | CMC Update article.

2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002

• Goldfinger LE, Ptak C, Jeffery ED, Shabanowitz J, Hunt DF, Ginsberg MH. RLIP76 (RalBP1) is an R-Ras effector that mediates adhesion-dependent Rac activation and cell migration. J Cell Biol 2006; 174 (6):877-88 PubMed | CMC Update article.
• Han J, Lim CJ, Watanabe N, Calderwood DA, Puzon-McLaughlin W, Lafuente EM, Boussiotis VA, Shattil SJ, Ginsberg MH. Reconstructing and Deconstructing Agonist-Induced Activation of Integrin alphaIIb beta3. Curr. Biol. 2006; 16 (18):1796-806 PubMed | CMC Update article.
• Luxenburg C, Parsons JT, Addadi L, Geiger B. Involvement of the Src-cortactin pathway in podosome formation and turnover during polarization of cultured osteoclasts. J Cell Sci 2006; 119:4878-88 PubMed | CMC Update article.
• Martin KH, Jeffery ED, Grigera PR, Shabanowitz J, Hunt DF, Parsons JT. Cortactin phosphorylation sites mapped by mass spectrometry. J Cell Sci. 2006; 119(Pt 14):2851-3. PubMed.
• Mayhew MW, Webb DJ, Kovalenko M, Whitmore L, Fox JW, Horwitz AF. Identification of Protein Networks Associated with the PAK1-betaPIX-GIT1-Paxillin Signaling Complex by Mass Spectromerty. J Proteome Res 2006; 5 (9):2417-23 PubMed | CMC Update article.
• Nayal A, Webb DJ, Brown CM, Schaefer EM, Vicente-Manzanares M, Horwitz AR. Paxillin phosphorylation at Ser273 localizes a GIT1–PIX–PAK complex and regulates adhesion and protrusion dynamics J. Cell Biol. 2006; 173(4):587-9. PubMed | CMC Update article.
• Sakakibara A, Horwitz AF. Mechanism of polarized protrusion formation on neuronal precursors migrating in the developing chicken cerebellum. J Cell Sci 2006; 119 (Pt 17):3583-92 PubMed | CMC Update article.
• Webb DJ, Kovalenko M, Whitmore L, Horwitz AF.Phosphorylation of serine 709 in GIT1 regulates protrusive activity in cells.Biochem Biophys Res Commun. 2006; 346(4):1284-8. PubMed | CMC Update article.
• Webb DJ, Mayhew MW, Kovalenko M, Schroeder MJ, Jeffery ED, Whitmore L, Shabanowitz J, Hunt DF, Horwitz AF. Identification of phosphorylation sites in GIT1. J Cell Sci. 2006; 119(Pt 14):2847-50. PubMed | CMC Update article.
• Wang Y, Hanley R, Klemke RL. Computational Methods for Comparison of Large Genomic and Proteomic Datasets Reveal Protein Markers of Metastatic Cancer. J Proteome Res. 2006; 5(4) :907-15. PubMed | CMC Update article.

2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002

• Coon JJ, Ueberheide B, Syka JE, Dryhurst DD, Ausio J, Shabanowitz J, Hunt DF. Protein identification using sequential ion/ion reactions and tandem mass spectrometry. Proc Natl Acad Sci U S A 2005; 102 (27):9463-8 PubMed
• Coon JJ, Shabanowitz J, Hunt DF, Syka JE. Electron transfer dissociation of peptide anions. J Am Soc Mass Spectrom 2005; 16 (6):880-2 PubMed
• Grigera PR, Jeffery ED, Martin KH, Shabanowitz J, Hunt DF, Parsons JT. FAK phosphorylation sites mapped by mass spectrometry. J Cell Sci. 2005; 118(Pt 21):4931-5. PubMed
• Ratnikov B, Ptak C, Han J, Shabanowitz J, Hunt DF, Ginsberg MH. Talin phosphorylation sites mapped by mass spectrometry. J Cell Sci. 2005; 118(Pt 21):4921-3. PubMed
• Schroeder MJ, Webb DJ, Shabanowitz J, Horwitz AF, Hunt DF. Methods for the detection of paxillin post-translational modifications and interacting proteins by mass spectrometry. J Proteome Res. 2005; 4(5):1832-41. PubMed
• Vicente-Manzanares M, Webb DJ, Horwitz AR. Cell migration at a glance. J Cell Sci. 2005; 118(Pt 21):4917-9. PubMed
• Webb DJ, Schroeder MJ, Brame CJ, Whitmore L, Shabanowitz J, Hunt DF, Horwitz AR. Paxillin phosphorylation sites mapped by mass spectrometry. J Cell Sci. 2005; 118(Pt 21):4925-9. PubMed

2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002

• Burridge K, Wennerberg K. Rho and Rac take center stage. Cell 2004; 116 (2):167-79. PubMed
• Peterson LJ, Rajfur Z, Maddox AS, Freel CD, Chen Y, Edlund M, Otey C, Burridge K. Simultaneous stretching and contraction of stress fibers in vivo. Mol Biol Cell. 2004; 15(7):3497-508. PubMed
• Syka JE, Coon JJ, Schroeder MJ, Shabanowitz J, Hunt DF. Peptide and protein sequence analysis by electron transfer dissociation mass spectrometry. Proc Natl Acad Sci U S A 2004; 101 (26):9528-33. PubMed

2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002

• Calderwood DA, Fujioka Y, de Pereda JM, Garcia-Alvarez B, Nakamoto T, Margolis B, McGlade CJ, Liddington RC, Ginsberg MH. Integrin beta cytoplasmic domain interactions with phosphotyrosine-binding domains: a structural prototype for diversity in integrin signaling.Proc Natl Acad Sci U S A. 2003; 100(5):2272-7. PubMed
• Garcia-Alvarez B, de Pereda JM, Calderwood DA, Ulmer TS, Critchley D, Campbell ID, Ginsberg MH, Liddington RC.Structural determinants of integrin recognition by talin. Mol Cell. 2003; 11(1):49-58. PubMed

2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002

• Ambroise Y, Yaspan B, Ginsberg MH, Boger DL. Inhibitors of cell migration that inhibit intracellular paxillin/alpha4 binding: a well-documented use of positional scanning libraries. Chem Biol. 2002; 9(11):1219-26. PubMed
• Manabe R, Kovalenko M, Webb DJ, Horwitz AR. GIT1 functions in a motile, multi-molecular signaling complex that regulates protrusive activity and cell migration. J Cell Sci. 2002; 115(Pt 7):1497-510. PubMed
• Murase S, Horwitz AF. Deleted in colorectal carcinoma and differentially expressed integrins mediate the directional migration of neural precursors in the rostral migratory stream. J Neurosci 2002; 22 (9):3568-79 PubMed
• Schwartz MA, Ginsberg MH. Networks and crosstalk: integrin signalling spreads. Nat Cell Biol 2002; 4 (4):E65-8 PubMed