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Drosophila Migration Gene Screens

wt-migratory_cells vs wt-non-migratory_cells

Ovaries were dissected from wild-type Drosophila females and dissociated into single cells as described. The border cells and centripetal cells (i.e. migratory cells) were separated from the remaining cells (i.e., non-migratory cells). RNA was isolated from migratory and non-migratory cells, reverse transcribed into cDNA and converted into labeled cRNA "targets" which were used to interrogate Affymetrix whole genome microarrays.

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  SymbolDescriptionMedian ValuesFold ChangeProbe ID
1 qkr58E-3
Flybase
Entrez
quaking related 58E-3Mig: 138.5
Non-Mig: 188.3
0.73551141202_at
2 CG2947
Flybase
Entrez
CG2947 gene product from transcript CG2947-RAMig: 104.6
Non-Mig: 160.7
0.65091141203_at
3 CG6453
Flybase
Entrez
CG6453 gene product from transcript CG6453-RAMig: 814.4
Non-Mig: 480.3
1.69560141204_at
4 alphaCop
Flybase
Entrez
CMCKB
alpha-coatomer proteinMig: 1484.7
Non-Mig: 937.2
1.58420141206_at
5 CG4453
Flybase
Entrez
CG4453 gene product from transcript CG4453-RCMig: 95.5
Non-Mig: 127.7
0.74783141207_at
6 Cpr
Flybase
Entrez
Cytochrome P450 reductaseMig: 109.2
Non-Mig: 169.4
0.64462141208_at
7 CG12135
Flybase
Entrez
CG12135 gene product from transcript CG12135-RAMig: 220.0
Non-Mig: 319.0
0.68966141209_at
8 Tim10
Flybase
Entrez
CG9878 gene product from transcript CG9878-RAMig: 1010.2
Non-Mig: 1770.4
0.57061141212_at
9 Gdi
Flybase
Entrez
CMCKB
GDP dissociation inhibitorMig: 1835.6
Non-Mig: 1312.0
1.39910141214_at
10 CG4338
Flybase
Entrez
CG4338 gene product from transcript CG4338-RAMig: 676.6
Non-Mig: 675.3
1.00190141215_at
11 Dak1
Flybase
Entrez
CG6092 gene product from transcript CG6092-RBMig: 609.4
Non-Mig: 782.2
0.77906141217_at
12 Hrb27C
Flybase
Entrez
CMCKB
Heterogeneous nuclear ribonucleoprotein at 27CMig: 928.5
Non-Mig: 720.0
1.28960141218_at
13 CG7099
Flybase
Entrez
CG7099 gene product from transcript CG7099-RAMig: 72.8
Non-Mig: 102.5
0.71023141219_at
14 CG14641
Flybase
Entrez
CG14641 gene product from transcript CG14641-RAMig: 864.7
Non-Mig: 763.2
1.13300141222_at
15 CG6838
Flybase
Entrez
CG6838 gene product from transcript CG6838-RAMig: 501.4
Non-Mig: 364.9
1.37410141224_at
16 CG6904
Flybase
Entrez
CG6904 gene product from transcript CG6904-RCMig: 144.6
Non-Mig: 138.4
1.04480141226_at
17 Rpn7
Flybase
Entrez
CG5378 gene product from transcript CG5378-RAMig: 1510.8
Non-Mig: 1645.9
0.91794141231_at
18 CG1103
Flybase
Entrez
CG1103 gene product from transcript CG1103-RAMig: 275.9
Non-Mig: 162.9
1.69370141240_at
19 CG8351
Flybase
Entrez
CG8351 gene product from transcript CG8351-RAMig: 475.5
Non-Mig: 649.7
0.73185141241_at
20 Mcm2
Flybase
Entrez
Minichromosome maintenance 2Mig: 94.0
Non-Mig: 147.5
0.63731141245_at