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Chemical Screens

Compounds, identified from the Natural products from HTS Tel Aviv University, Israel, that perturb migration-related structures in REF52 cells expressing YFP-paxillin.

If you are interested in any of the compounds (identified below by their screening ID number) or would like further information on specific compounds, please contact:

Prof. Benny Geiger
Dept. of Molecular Biology
The Weizmann Institute of Science
Rehovot 76100, ISRAEL

Tel: ++972-8-934 3910 or 4069
FAX: ++972-8-946 5607 or 4125
email: benny.geiger@weizmann.ac.il
Geiger WWW site
ID code Phenotype Montage HR image

control Normal FA morphology montage image

BG2-1 Destroy actin skeleton montage image
BG2-2 1:100 destroy actin, 1:1000 small FA. montage image
BG2-3 Destroy actin skeleton montage image
BG2-4 Loss of FA montage image
BG2-5 Loss of FA montage image
BG2-6 FA Elongation montage image
BG2-7 Dispersed cell morphology. Enhanced peripherial FA. montage image
BG2-8 Pertrusions, Loss of FA. montage image
BG2-9 1:100 toxic, 1:1000 Enhanced peripherial FA. montage image
BG2-10 Enhanced peripherial FA. montage image
BG2-11 Large cells. Loss of FA montage image
BG2-12 1:100 toxic, 1:1000 large cells. montage image
BG2-13 1:100 toxic, 1:1000 Loss of FA, destroy actin montage image
BG2-14 Enhanced peripherial FA. montage image
BG2-15 Cell Contraction montage image
BG2-16 Enhanced peripherial FA. montage image
BG2-17 Toxic. Focals residues. montage