2011 Structure

• CARD-Mediated Autoinhibition of cIAP1's E3 Ligase Activity Suppresses Cell Proliferation and Migration

  Lopez, Juanita et al.
  Molecular Cell 42
  (1 June 2011); doi: 10.1016/j.molcel.2011.04.008

  Abstract

• NMR analysis of the  IIb 3 cytoplasmic interaction suggests a mechanism for integrin regulation

  Metcalf, D. G. et al.
  Proceedings of the National Academy of Sciences 107
  (28 December 2010); doi: 10.1073/pnas.1015545107

  Abstract

• Actin-Based Motility: WAVE Regulatory Complex Structure Reopens Old SCARs

  Davidson, Andrew J. and Insall, Robert H.
  Current Biology 21
  (1 January 2011); doi: 10.1016/j.cub.2010.12.001

  Abstract

• Electron tomography reveals a flared morphology on growing microtubule ends

  Hoog, J. L. et al.
  Journal of Cell Science 124
  (1 March 2011); doi: 10.1242/jcs.072967

  Abstract

• Structural basis for the slow dynamics of the actin filament pointed end

  Narita, Akihiro, Oda, Toshiro and Maéda, Yuichiro
  The EMBO Journal 30 1230 - 1237
  (4 March 2011); doi: 10.1038/emboj.2011.48

  Abstract

• Structural Requirements for Activation in  IIb 3 Integrin

  Kamata, T. et al.
  Journal of Biological Chemistry 285
  (3 December 2010); doi: 10.1074/jbc.M110.139667

  Abstract

• Structure and function of the interacting domains of Spire and Fmn-family formins

  Vizcarra, C. L. et al.
  Proceedings of the National Academy of Sciences 108
  (19 July 2011); doi: 10.1073/pnas.1105703108

  Abstract

• PNAS Plus: Arp2/3 complex is bound and activated by two WASP proteins

  Padrick, S. B. et al.
  Proceedings of the National Academy of Sciences
  (15 June 2011); doi: 10.1073/pnas.1100236108

  Abstract

• Multiscale simulations suggest a mechanism for integrin inside-out activation CMC

  Kalli, A. C., Campbell, I. D. and Sansom, M. S. P.
  Proceedings of the National Academy of Sciences 108
  (19 July 2011); doi: 10.1073/pnas.1104505108

  Abstract

• PNAS Plus: Structural and biochemical characterization of two binding sites for nucleation-promoting factor WASp-VCA on Arp2/3 complex

  Ti, S.-C., Jurgenson, C. T., Nolen, B. J. and Pollard, T. D.
  Proceedings of the National Academy of Sciences
  (15 June 2011); doi: 10.1073/pnas.1100125108

  Abstract

• Raf-induced MMP9 disrupts tissue architecture of human breast cells in three-dimensional culture and is necessary for tumor growth in vivo

  Beliveau, A. et al.
  Genes & Development 24
  (15 December 2010); doi: 10.1101/gad.1990410

  Abstract

• Mechanistic Insights into Specificity, Activity, and Regulatory Elements of the Regulator of G-protein Signaling (RGS)-containing Rho-specific Guanine Nucleotide Exchange Factors (GEFs) p115, PDZ-RhoGEF (PRG), and Leukemia-associated RhoGEF (LARG)

  Jaiswal, M. et al.
  Journal of Biological Chemistry 286
  (20 May 2011); doi: 10.1074/jbc.M111.226431

  Abstract

• Structure-Function Analysis of Tetraspanin CD151 Reveals Distinct Requirements for Tumor Cell Behaviors Mediated by  3 1 versus  6 4 Integrin

  Zevian, S., Winterwood, N. E. and Stipp, C. S.
  Journal of Biological Chemistry 286
  (4 March 2011); doi: 10.1074/jbc.M110.173583

  Abstract

• Vinculin Activation Is Necessary for Complete Talin Binding

  Golji, Javad, Lam, Johnny and Mofrad, Mohammad R.K.
  Biophysical Journal 100
  (19 January 2011); doi: 10.1016/j.bpj.2010.11.024

  Abstract

• Specific Syndecan-1 Domains Regulate Mesenchymal Tumor Cell Adhesion, Motility and Migration

  Zong, Fang et al.
  PLoS ONE 6
  (23 June 2011); doi: 10.1371/journal.pone.0014816

  Abstract

• Crystal Structure of a Coiled-Coil Domain from Human ROCK I

  Tu, Daqi et al.
  PLoS ONE 6
  (21 March 2011); doi: 10.1371/journal.pone.0018080

  Abstract