Subject archive
2011 Signalling
Cancer Cells Exploit the Eph-Ephrin System to Promote Invasion and Metastasis: Tales of Unwitting Partners
Wang, B.
Science Signaling 4
(31 May 2011); doi: 10.1126/scisignal.2002153Enforced hematopoietic cell E- and L-selectin ligand (HCELL) expression primes transendothelial migration of human mesenchymal stem cells
Thankamony, S. P. and Sackstein, R.
Proceedings of the National Academy of Sciences 108
(8 February 2011); doi: 10.1073/pnas.1018064108How Cells Use Pseudopods for Persistent Movement and Navigation
Van haastert, P. J. M.
Science Signaling 4
(8 February 2011); doi: 10.1126/scisignal.2001708Life at the Leading Edge
Ridley, Anne J.
Cell 145
(1 June 2011); doi: 10.1016/j.cell.2011.06.010VHL loss in renal cell carcinoma leads to up-regulation of CUB domain-containing protein 1 to stimulate PKC -driven migration
Razorenova, O. V. et al.
Proceedings of the National Academy of Sciences 108
(1 February 2011); doi: 10.1073/pnas.1011777108Proinvasion Metastasis Drivers in Early-Stage Melanoma Are Oncogenes
Scott, Kenneth L. et al.
Cancer Cell 20
(1 July 2011); doi: 10.1016/j.ccr.2011.05.025Tumor-Derived Jagged1 Promotes Osteolytic Bone Metastasis of Breast Cancer by Engaging Notch Signaling in Bone Cells
Sethi, Nilay, Dai, Xudong, Winter, Christopher G. and Kang, Yibin
Cancer Cell 19
(15 February 2011); doi: 10.1016/j.ccr.2010.12.022Proneural Transcription Factors Regulate Different Steps of Cortical Neuron Migration through Rnd-Mediated Inhibition of RhoA Signaling
Pacary, Emilie et al.
Neuron 69
(1 March 2011); doi: 10.1016/j.neuron.2011.02.018CUB-domain-containing protein 1 (CDCP1) activates Src to promote melanoma metastasis CMC
Liu, H. et al.
Proceedings of the National Academy of Sciences 108
(25 January 2011); doi: 10.1073/pnas.1017228108Ephrin-Mediated cis-Attenuation of Eph Receptor Signaling Is Essential for Spinal Motor Axon Guidance
Kao, Tzu-Jen and Kania, Artur
Neuron 71
(1 July 2011); doi: 10.1016/j.neuron.2011.05.031N-α-Acetyltransferase 10 Protein Suppresses Cancer Cell Metastasis by Binding PIX Proteins and Inhibiting Cdc42/Rac1 Activity
Hua, Kuo-Tai et al.
Cancer Cell 19
(15 February 2011); doi: 10.1016/j.ccr.2010.11.010SH3BP1, an Exocyst-Associated RhoGAP, Inactivates Rac1 at the Front to Drive Cell Motility
Parrini, Maria Carla et al.
Molecular Cell 42
(1 June 2011); doi: 10.1016/j.molcel.2011.03.032Amphiregulin Exosomes Increase Cancer Cell Invasion
Higginbotham, James N. et al.
Current Biology 21
(1 May 2011); doi: 10.1016/j.cub.2011.03.043Reelin Regulates Cadherin Function via Dab1/Rap1 to Control Neuronal Migration and Lamination in the Neocortex
Franco, Santos J. et al.
Neuron 69
(10 February 2011); doi: 10.1016/j.neuron.2011.01.003Pak1 regulates focal adhesion strength, myosin IIA distribution, and actin dynamics to optimize cell migration
Delorme-walker, V. D. et al.
The Journal of Cell Biology 193
(27 June 2011); doi: 10.1083/jcb.201010059RhoA and RhoC have distinct roles in migration and invasion by acting through different targets
Vega, F. M., Fruhwirth, G., Ng, T. and Ridley, A. J.
The Journal of Cell Biology 193
(16 May 2011); doi: 10.1083/jcb.201011038Oncogenic BRAF Induces Melanoma Cell Invasion by Downregulating the cGMP-Specific Phosphodiesterase PDE5A
Arozarena, Imanol et al.
Cancer Cell 19
(18 January 2011); doi: 10.1016/j.ccr.2010.10.029Phosphoinositide 3-kinase signaling pathway mediated by p110 regulates invadopodia formation
Yamaguchi, H. et al.
The Journal of Cell Biology 193
(27 June 2011); doi: 10.1083/jcb.201009126ERK-MAPK Drives Lamellipodia Protrusion by Activating the WAVE2 Regulatory Complex CMC
Mendoza, Michelle C. et al.
Molecular Cell 41
(1 March 2011); doi: 10.1016/j.molcel.2011.02.031SH3YL1 regulates dorsal ruffle formation by a novel phosphoinositide-binding domain
Hasegawa, J. et al.
The Journal of Cell Biology 193
(30 May 2011); doi: 10.1083/jcb.201012161Whence Directionality: Guidance Mechanisms in Solitary and Collective Cell Migration
Rørth, Pernille
Developmental Cell 20
(18 January 2011); doi: 10.1016/j.devcel.2010.12.014Profilin1 regulates PI(3,4)P2 and lamellipodin accumulation at the leading edge thus influencing motility of MDA-MB-231 cells
Bae, Y. H. et al.
Proceedings of the National Academy of Sciences 107
(14 December 2010); doi: 10.1073/pnas.1002309107Control of Local Rho GTPase Crosstalk by Abr
Vaughan, Emily M., Miller, Ann L., Yu, Hoi-Ying E. and Bement, William M.
Current Biology 21
(22 February 2011); doi: 10.1016/j.cub.2011.01.014PDZ-RhoGEF ubiquitination by Cullin3-KLHL20 controls neurotrophin-induced neurite outgrowth
Lin, M.-Y. et al.
The Journal of Cell Biology 193
(13 June 2011); doi: 10.1083/jcb.201103015CXCR4 and CXCR7 Have Distinct Functions in Regulating Interneuron Migration
Wang, Yanling et al.
Neuron 69
(1 January 2011); doi: 10.1016/j.neuron.2010.12.005Phosphorylation of CSF-1R Y721 mediates its association with PI3K to regulate macrophage motility and enhancement of tumor cell invasion CMC
Sampaio, N. G. et al.
Journal of Cell Science 124
(15 June 2011); doi: 10.1242/jcs.075309Cxcr7 Controls Neuronal Migration by Regulating Chemokine Responsiveness
Sánchez-alcañiz, Juan Antonio et al.
Neuron 69
(1 January 2011); doi: 10.1016/j.neuron.2010.12.006Cell behaviors regulated by guidance cues in collective migration of border cells
Poukkula, M., Cliffe, A., Changede, R. and Rorth, P.
The Journal of Cell Biology 192
(7 February 2011); doi: 10.1083/jcb.201010003Actin-Based Motility: WAVE Regulatory Complex Structure Reopens Old SCARs
Davidson, Andrew J. and Insall, Robert H.
Current Biology 21
(1 January 2011); doi: 10.1016/j.cub.2010.12.001Identification of PTPN23 as a novel regulator of cell invasion in mammary epithelial cells from a loss-of-function screen of the 'PTP-ome'
Lin, G., Aranda, V., Muthuswamy, S. K. and Tonks, N. K.
Genes & Development 25
(1 July 2011); doi: 10.1101/gad.2018911Kindlin-2 regulates podocyte adhesion and fibronectin matrix deposition through interactions with phosphoinositides and integrins
Qu, H. et al.
Journal of Cell Science 124
(15 March 2011); doi: 10.1242/jcs.076976FLRT2 and FLRT3 act as repulsive guidance cues for Unc5-positive neurons
Yamagishi, Satoru et al.
The EMBO Journal 30 2920 - 2933
(14 June 2011); doi: 10.1038/emboj.2011.189Rho GTPases and their role in organizing the actin cytoskeleton
Sit, S.-T. and Manser, E.
Journal of Cell Science 124
(1 March 2011); doi: 10.1242/jcs.064964Mena invasive (MenaINV) promotes multicellular streaming motility and transendothelial migration in a mouse model of breast cancer
Roussos, E. T. et al.
Journal of Cell Science 124
(1 July 2011); doi: 10.1242/jcs.086231Asymmetric localisation of cytokine mRNA is essential for JAK/STAT activation during cell invasiveness
Van de bor, V. et al.
Development 138
(1 April 2011); doi: 10.1242/dev.056184Adhesion signalling complexes
Byron, Adam, Morgan, Mark R. and Humphries, Martin J.
Current Biology 20
(1 December 2010); doi: 10.1016/j.cub.2010.10.059The death receptor CD95 activates the cofilin pathway to stimulate tumour cell invasion
Steller, Ernst J A et al.
EMBO reports
(15 July 2011); doi: 10.1038/embor.2011.129Sphingosine 1-phosphate regulates matrix metalloproteinase-9 expression and breast cell invasion through S1P3-G q coupling
Kim, E.-S. et al.
Journal of Cell Science 124
(1 July 2011); doi: 10.1242/jcs.076794β1 integrins regulate fibroblast chemotaxis through control of N-WASP stability
King, Samantha J et al.
The EMBO Journal 30 1705 - 1718
(22 March 2011); doi: 10.1038/emboj.2011.82Netrins: versatile extracellular cues with diverse functions
Sun, K. L. W., Correia, J. P. and Kennedy, T. E.
Development 138
(1 June 2011); doi: 10.1242/dev.044529RhoGDI -dependent balance between RhoA and RhoC is a key regulator of cancer cell tumorigenesis.
Ho, T. T. G. et al.
Molecular Biology of the Cell
(14 July 2011); doi: 10.1091/mbc.E11-01-0020Phosphorylation of Ser 402 impedes phosphatase activity of slingshot 1
Barišić, Sandra et al.
EMBO reports 12 527 - 533
(28 April 2011); doi: 10.1038/embor.2011.53Interaction of the Human Prostacyclin Receptor with the PDZ adapter protein PDZK1: Role in Endothelial Cell Migration and Angiogenesis
Turner, E. C., Mulvaney, E. P., Reid, H. M. and Kinsella, B. T.
Molecular Biology of the Cell
(8 June 2011); doi: 10.1091/mbc.E11-04-0374Functional Cooperation between the Proteins Nck and ADAP Is Fundamental for Actin Reorganization
Pauker, M. H. et al.
Molecular and Cellular Biology 31
(1 July 2011); doi: 10.1128/MCB.01358-10A direct interaction between the large GTPase dynamin-2 and FAK regulates focal adhesion dynamics in response to active Src
Wang, Y., Cao, H., Chen, J. and Mcniven, M. A.
Molecular Biology of the Cell 22
(1 May 2011); doi: 10.1091/mbc.E10-09-0785An association between NUAK2 and MRIP reveals a novel mechanism for regulation of actin stress fibers
Vallenius, T. et al.
Journal of Cell Science 124
(1 February 2011); doi: 10.1242/jcs.072660Abl Kinases Are Required for Invadopodia Formation and Chemokine-induced Invasion
Smith-pearson, P. S., Greuber, E. K., Yogalingam, G. and Pendergast, A. M.
Journal of Biological Chemistry 285
(17 December 2010); doi: 10.1074/jbc.M110.147330Anchored Protein Kinase A Recruitment of Active Rac GTPase
Logue, J. S. et al.
Journal of Biological Chemistry 286
(24 June 2011); doi: 10.1074/jbc.M111.232660Regulation of Lung Cancer Cell Migration and Invasion by Reactive Oxygen Species and Caveolin-1
Luanpitpong, S. et al.
Journal of Biological Chemistry 285
(10 December 2010); doi: 10.1074/jbc.M110.124958Regulation of cofilin phosphorylation and asymmetry in collective cell migration during morphogenesis
Zhang, L. et al.
Development 138
(1 February 2011); doi: 10.1242/dev.046870R-Ras and Rac GTPase Cross-talk Regulates Hematopoietic Progenitor Cell Migration, Homing, and Mobilization
Shang, X. et al.
Journal of Biological Chemistry 286
(8 July 2011); doi: 10.1074/jbc.M111.226951FOXA2 functions as a suppressor of tumor metastasis by inhibition of epithelial-to-mesenchymal transition in human lung cancers
Tang, Yunneng et al.
Cell Research 21 316 - 326
(7 September 2010); doi: 10.1038/cr.2010.126Cdc42-dependent formation of the ZO-1/MRCKβ complex at the leading edge controls cell migration
Huo, Lin et al.
The EMBO Journal 30 665 - 678
(14 January 2011); doi: 10.1038/emboj.2010.353Rapamycin Inhibits Cytoskeleton Reorganization and Cell Motility by Suppressing RhoA Expression and Activity
Liu, L. et al.
Journal of Biological Chemistry 285
(3 December 2010); doi: 10.1074/jbc.M110.141168Neuropilin-1 Signaling through p130Cas Tyrosine Phosphorylation Is Essential for Growth Factor-Dependent Migration of Glioma and Endothelial Cells
Evans, I. M. et al.
Molecular and Cellular Biology 31
(15 March 2011); doi: 10.1128/MCB.00903-10Pancreatic Cancer Cells Respond to Type I Collagen by Inducing Snail Expression to Promote Membrane Type 1 Matrix Metalloproteinase-dependent Collagen Invasion
Shields, M. A. et al.
Journal of Biological Chemistry 286
(25 March 2011); doi: 10.1074/jbc.M110.195628Phosphorylation of STEF/Tiam2 by protein kinase A is critical for Rac1 activation and neurite outgrowth in dibutyryl cAMP-treated PC12D cells
Goto, A., Hoshino, M., Matsuda, M. and Nakamura, T.
Molecular Biology of the Cell 22
(15 May 2011); doi: 10.1091/mbc.E10-09-0783SUMO wrestling in cell movement
Rytinki, Miia M and Palvimo, Jorma J
Cell Research 21 3 - 5
(23 November 2010); doi: 10.1038/cr.2010.162NFATC1 promotes epicardium-derived cell invasion into myocardium
Combs, M. D. et al.
Development 138
(1 May 2011); doi: 10.1242/dev.060996Phosphorylation of Trask by Src Kinases Inhibits Integrin Clustering and Functions in Exclusion with Focal Adhesion Signaling
Spassov, D. S. et al.
Molecular and Cellular Biology 31
(15 February 2011); doi: 10.1128/MCB.00841-10RACK1 Regulates VEGF/Flt1-mediated Cell Migration via Activation of a PI3K/Akt Pathway
Wang, F. et al.
Journal of Biological Chemistry 286
(18 March 2011); doi: 10.1074/jbc.M110.165605Mechanisms of mechanical signaling in development and disease
Janmey, P. A. and Miller, R. T.
Journal of Cell Science 124
(1 January 2011); doi: 10.1242/jcs.071001Endocytosis of EphA receptors is essential for the proper development of the retinocollicular topographic map
Yoo, Sooyeon et al.
The EMBO Journal 30 1593 - 1607
(22 February 2011); doi: 10.1038/emboj.2011.44Cooperative Signaling between Slit2 and Ephrin-A1 Regulates a Balance between Angiogenesis and Angiostasis
Dunaway, C. M. et al.
Molecular and Cellular Biology 31
(1 February 2011); doi: 10.1128/MCB.00667-10Disrupted-in-Schizophrenia 1-mediated axon guidance involves TRIO-RAC-PAK small GTPase pathway signaling
Chen, S.-Y., Huang, P.-H. and Cheng, H.-J.
Proceedings of the National Academy of Sciences 108
(5 April 2011); doi: 10.1073/pnas.1018128108GRB2 couples RhoU to epidermal growth factor receptor signaling and cell migration
Zhang, J.-S., Koenig, A., Young, C. and Billadeau, D. D.
Molecular Biology of the Cell 22
(15 June 2011); doi: 10.1091/mbc.E10-12-0969The Rho Target PRK2 Regulates Apical Junction Formation in Human Bronchial Epithelial Cells
Wallace, S. W., Magalhaes, A. and Hall, A.
Molecular and Cellular Biology 31
(1 January 2011); doi: 10.1128/MCB.01001-10Asymmetric PI(3,4,5)P3 and Akt Signaling Mediates Chemotaxis of Axonal Growth Cones
Henle, S. J. et al.
Journal of Neuroscience 31
(11 May 2011); doi: 10.1523/JNEUROSCI.0216-11.2011Mechanisms of plasma membrane targeting of formin mDia2 through its amino terminal domains
Gorelik, R. et al.
Molecular Biology of the Cell 22
(15 January 2011); doi: 10.1091/mbc.E10-03-0256Syk Regulates Multiple Signaling Pathways Leading to CX3CL1 Chemotaxis in Macrophages
Park, H. and Cox, D.
Journal of Biological Chemistry 286
(29 April 2011); doi: 10.1074/jbc.M110.185181Computational Analysis of the Spatiotemporal Coordination of Polarized PI3K and Rac1 Activities in Micro-Patterned Live Cells
Lu, Shaoying et al.
PLoS ONE 6
(27 June 2011); doi: 10.1371/journal.pone.0021293Mechanical stiffness grades metastatic potential in patient tumor cells and in cancer cell lines
Swaminathan, V. et al.
Cancer Research
(3 June 2011); doi: 10.1158/0008-5472.CAN-11-0247Sphingosine 1-Phosphate-Induced Motility and Endocytosis of Dendritic Cells Is Regulated by SWAP-70 through RhoA
Ocana-morgner, C. et al.
The Journal of Immunology 186
(1 May 2011); doi: 10.4049/jimmunol.1003461The kinesin KIF9 and reggie/flotillin proteins regulate matrix degradation by macrophage podosomes
Cornfine, S. et al.
Molecular Biology of the Cell 22
(15 January 2011); doi: 10.1091/mbc.E10-05-03941A Integrin Is a Master Regulator of Invadosome Organization and Function
Destaing, O. et al.
Molecular Biology of the Cell 21
(1 December 2010); doi: 10.1091/mbc.E10-07-0580c-Jun N-terminal Kinase 2 (JNK2) Enhances Cell Migration through Epidermal Growth Factor Substrate 8 (EPS8)
Mitra, S., Lee, J.-S., Cantrell, M. and Van den berg, C. L.
Journal of Biological Chemistry 286
(29 April 2011); doi: 10.1074/jbc.M109.094441FAK phosphorylation at Tyr-925 regulates cross-talk between focal adhesion turnover and cell protrusion
Deramaudt, T. B. et al.
Molecular Biology of the Cell 22
(1 April 2011); doi: 10.1091/mbc.E10-08-0725Phosphorylation of Serine 68 of Twist1 by MAPKs Stabilizes Twist1 Protein and Promotes Breast Cancer Cell Invasiveness
Hong, J. et al.
Cancer Research 71
(1 June 2011); doi: 10.1158/0008-5472.CAN-10-2914Macrophage Migration Inhibitory Factor and CD74 Regulate Macrophage Chemotactic Responses via MAPK and Rho GTPase
Fan, H. et al.
The Journal of Immunology 186
(15 April 2011); doi: 10.4049/jimmunol.1003713WAVE2 Forms a Complex with PKA and Is Involved in PKA Enhancement of Membrane Protrusions
Yamashita, H., Ueda, K. and Kioka, N.
Journal of Biological Chemistry 286
(4 February 2011); doi: 10.1074/jbc.M110.145409c-Src-Mediated Phosphorylation of NoxA1 and Tks4 Induces the Reactive Oxygen Species (ROS)-Dependent Formation of Functional Invadopodia in Human Colon Cancer Cells
Gianni, D., Taulet, N., Dermardirossian, C. and Bokoch, G. M.
Molecular Biology of the Cell 21
(1 December 2010); doi: 10.1091/mbc.E10-08-0685Immunoinhibitory Adapter Protein Src Homology Domain 3 Lymphocyte Protein 2 (SLy2) Regulates Actin Dynamics and B Cell Spreading
Von holleben, M. et al.
Journal of Biological Chemistry 286
(15 April 2011); doi: 10.1074/jbc.M110.155184Distinct roles for paxillin and Hic-5 in regulating breast cancer cell morphology, invasion, and metastasis
Deakin, N. O. and Turner, C. E.
Molecular Biology of the Cell 22
(1 February 2011); doi: 10.1091/mbc.E10-09-0790Diosgenin, a Steroidal Saponin, Inhibits Migration and Invasion of Human Prostate Cancer PC-3 Cells by Reducing Matrix Metalloproteinases Expression
Chen, Pin-Shern et al.
PLoS ONE 6
(23 May 2011); doi: 10.1371/journal.pone.0020164Pregnane X Receptor PXR Activates the GADD45 Gene, Eliciting the p38 MAPK Signal and Cell Migration
Kodama, S. and Negishi, M.
Journal of Biological Chemistry 286
(4 February 2011); doi: 10.1074/jbc.M110.179812Rif-mDia1 Interaction Is Involved in Filopodium Formation Independent of Cdc42 and Rac Effectors
Goh, W. I. et al.
Journal of Biological Chemistry 286
(15 April 2011); doi: 10.1074/jbc.M110.182683Src and Caveolin-1 Reciprocally Regulate Metastasis via a Common Downstream Signaling Pathway in Bladder Cancer CMC
Thomas, S. et al.
Cancer Research 71
(1 February 2011); doi: 10.1158/0008-5472.CAN-10-0730Regulatory Domain Selectivity in the Cell-Type Specific PKN-Dependence of Cell Migration
Lachmann, Sylvie et al.
PLoS ONE 6
(6 July 2011); doi: 10.1371/journal.pone.0021732mTORC1 and mTORC2 Regulate EMT, Motility, and Metastasis of Colorectal Cancer via RhoA and Rac1 Signaling Pathways
Gulhati, P. et al.
Cancer Research 71
(1 May 2011); doi: 10.1158/0008-5472.CAN-10-4058Dynamic molecular processes mediate cellular mechanotransduction
Hoffman, Brenton D., Grashoff, Carsten and Schwartz, Martin A.
Nature 475 316 - 323
(20 July 2011); doi: 10.1038/nature10316The Naturally Processed CD95L Elicits a c-Yes/Calcium/PI3K-Driven Cell Migration Pathway
Tauzin, Sébastien et al.
PLoS Biology 9
(21 June 2011); doi: 10.1371/journal.pbio.1001090Rho Kinase Phosphorylation Promotes Ezrin-Mediated Metastasis in Hepatocellular Carcinoma
Chen, Y. et al.
Cancer Research 71
(1 March 2011); doi: 10.1158/0008-5472.CAN-09-4683Vascular Endothelial Growth Factor A (VEGF-A) Induces Endothelial and Cancer Cell Migration through Direct Binding to Integrin 9 1: IDENTIFICATION OF A SPECIFIC 9 1 BINDING SITE
Oommen, S., Gupta, S. K. and Vlahakis, N. E.
Journal of Biological Chemistry 286
(14 January 2011); doi: 10.1074/jbc.M110.175158The 'invisible hand': regulation of RHO GTPases by RHOGDIs
Garcia-mata, Rafael, Boulter, Etienne and Burridge, Keith
Nature Reviews Molecular Cell Biology 12 493 - 504
(22 July 2011); doi: 10.1038/nrm3153Endothelial Cell-Specific Molecule 2 (ECSM2) Localizes to Cell-Cell Junctions and Modulates bFGF-Directed Cell Migration via the ERK-FAK Pathway
Shi, Chunwei et al.
PLoS ONE 6
(24 June 2011); doi: 10.1371/journal.pone.0021482DISC1-dependent switch from progenitor proliferation to migration in the developing cortex
Ishizuka, Koko et al.
Nature 473 92 - 96
(6 April 2011); doi: 10.1038/nature09859Murine Missing in Metastasis (MIM) Mediates Cell Polarity and Regulates the Motility Response to Growth Factors
Yu, Dan et al.
PLoS ONE 6
(9 June 2011); doi: 10.1371/journal.pone.0020845Protein kinase A governs a RhoA–RhoGDI protrusion–retraction pacemaker in migrating cells CMC
Tkachenko, Eugene et al.
Nature Cell Biology 13 660 - 667
(15 May 2011); doi: 10.1038/ncb2231Evidence That the Lipid Phosphatase SHIP-1 Regulates T Lymphocyte Morphology and Motility
Harris, S. J. et al.
The Journal of Immunology 186
(15 April 2011); doi: 10.4049/jimmunol.1002350Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs
Oskarsson, Thordur et al.
Nature Medicine 17 867 - 874
(26 June 2011); doi: 10.1038/nm.2379The Rho GEFs LARG and GEF-H1 regulate the mechanical response to force on integrins
Guilluy, Christophe et al.
Nature Cell Biology 13 722 - 727
(15 May 2011); doi: 10.1038/ncb2254Integrin Activation Promotes Axon Growth on Inhibitory Chondroitin Sulfate Proteoglycans by Enhancing Integrin Signaling
Tan, C. L. et al.
Journal of Neuroscience 31
(27 April 2011); doi: 10.1523/JNEUROSCI.0008-11.2011A cascade of protein kinase C isozymes promotes cytoskeletal polarization in T cells
Quann, Emily J, Liu, Xin, Altan-bonnet, Grégoire and Huse, Morgan
Nature Immunology 12 647 - 654
(22 May 2011); doi: 10.1038/ni.2033p190RhoGEF (Rgnef) Promotes Colon Carcinoma Tumor Progression via Interaction with Focal Adhesion Kinase
Yu, H.-G. et al.
Cancer Research 71
(15 January 2011); doi: 10.1158/0008-5472.CAN-10-2894Robo1 Regulates Semaphorin Signaling to Guide the Migration of Cortical Interneurons through the Ventral Forebrain
Hernandez-miranda, L. R. et al.
Journal of Neuroscience 31
(20 April 2011); doi: 10.1523/JNEUROSCI.5464-10.2011The insider's guide to leukocyte integrin signalling and function
Hogg, Nancy, Patzak, Irene and Willenbrock, Frances
Nature Reviews Immunology 11 416 - 426
(20 May 2011); doi: 10.1038/nri2986A Novel Sialyltransferase Inhibitor Suppresses FAK/Paxillin Signaling and Cancer Angiogenesis and Metastasis Pathways
Chen, J.-Y. et al.
Cancer Research 71
(15 January 2011); doi: 10.1158/0008-5472.CAN-10-1303In Chemotaxing Fibroblasts, Both High-Fidelity and Weakly Biased Cell Movements Track the Localization of PI3K Signaling CMC
Melvin, Adam T. et al.
Biophysical Journal 100
(1 April 2011); doi: 10.1016/j.bpj.2011.02.047Chronicles of the GTPase switch
Cherfils, Jacqueline and Zeghouf, Mahel
Nature Chemical Biology 7 493 - 495
(18 July 2011); doi: 10.1038/nchembio.608An EGFR-Src-Arg-Cortactin Pathway Mediates Functional Maturation of Invadopodia and Breast Cancer Cell Invasion CMC
Mader, C. C. et al.
Cancer Research 71
(1 March 2011); doi: 10.1158/0008-5472.CAN-10-1432GPR54 (KISS1R) Transactivates EGFR to Promote Breast Cancer Cell Invasiveness
Zajac, Mateusz et al.
PLoS ONE 6
(28 June 2011); doi: 10.1371/journal.pone.0021599SCFAs Induce Mouse Neutrophil Chemotaxis through the GPR43 Receptor
Vinolo, Marco A. R. et al.
PLoS ONE 6
(15 June 2011); doi: 10.1371/journal.pone.0021205GluA2 (GluR2) Regulates Metabotropic Glutamate Receptor-Dependent Long-Term Depression through N-Cadherin-Dependent and Cofilin-Mediated Actin Reorganization
Zhou, Z. et al.
Journal of Neuroscience 31
(19 January 2011); doi: 10.1523/JNEUROSCI.3869-10.2011Ligand-independent activation of c-Met by fibronectin and α5β1-integrin regulates ovarian cancer invasion and metastasis
Mitra, A K et al.
Oncogene 30 1566 - 1576
(29 November 2010); doi: 10.1038/onc.2010.532Signaling Network Triggers and Membrane Physical Properties Control the Actin Cytoskeleton-Driven Isotropic Phase of Cell Spreading
Rangamani, Padmini et al.
Biophysical Journal 100
(16 February 2011); doi: 10.1016/j.bpj.2010.12.3732Signal integration and crosstalk during thymocyte migration and emigration
Love, Paul E. and Bhandoola, Avinash
Nature Reviews Immunology 11 469 - 477
(24 June 2011); doi: 10.1038/nri2989Metabolism, migration and memory in cytotoxic T cells
Finlay, David and Cantrell, Doreen A.
Nature Reviews Immunology 11 109 - 117
(14 January 2011); doi: 10.1038/nri2888A biosensor generated via high-throughput screening quantifies cell edge Src dynamics
Gulyani, Akash et al.
Nature Chemical Biology 7
(12 June 2011); doi: 10.1038/nchembio.585Tumour-infiltrating regulatory T cells stimulate mammary cancer metastasis through RANKL–RANK signalling
Tan, Wei et al.
Nature 470 548 - 553
(16 February 2011); doi: 10.1038/nature09707Phospholipid-dependent regulation of the motor activity of myosin X
Umeki, Nobuhisa et al.
Nature Structural & Molecular Biology 18 783 - 788
(12 June 2011); doi: 10.1038/nsmb.2065IL-6 Stabilizes Twist and Enhances Tumor Cell Motility in Head and Neck Cancer Cells through Activation of Casein Kinase 2
Su, Ying-Wen et al.
PLoS ONE 6
(29 April 2011); doi: 10.1371/journal.pone.0019412Simultaneous siRNA Targeting of Src and Downstream Signaling Molecules Inhibit Tumor Formation and Metastasis of a Human Model Breast Cancer Cell Line
Bjorge, Jeffrey D. et al.
PLoS ONE 6
(26 April 2011); doi: 10.1371/journal.pone.0019309Ephrin Bs are essential components of the Reelin pathway to regulate neuronal migration
Sentürk, Aycan et al.
Nature 472 356 - 360
(3 April 2011); doi: 10.1038/nature09874miRNA regulation of Sdf1 chemokine signaling provides genetic robustness to germ cell migration
Staton, Alison A, Knaut, Holger and Giraldez, Antonio J
Nature Genetics 43 204 - 211
(23 January 2011); doi: 10.1038/ng.758Local, persistent activation of Rho GTPases during plasticity of single dendritic spines
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