Subject archive
2010 Signalling
Increased cell migration and plasticity in Nrf2-deficient cancer cell lines
Rachakonda, G et al.
Oncogene 29 3703 - 3714
(3 May 2010); doi: 10.1038/onc.2010.118Btbd7 Regulates Epithelial Cell Dynamics and Branching Morphogenesis
Onodera, T. et al.
Science 329
(30 July 2010); doi: 10.1126/science.1191880Modeling of Protrusion Phenotypes Driven by the Actin-Membrane Interaction
Enculescu, Mihaela, Sabouri-ghomi, Mohsen, Danuser, Gaudenz and Falcke, Martin
Biophysical Journal 98
(21 April 2010); doi: 10.1016/j.bpj.2009.12.4311A Rap/Phosphatidylinositol 3-Kinase Pathway Controls Pseudopod Formation
Kortholt, A. et al.
Molecular Biology of the Cell 21
(15 March 2010); doi: 10.1091/mbc.e09-03-0177TGFβ signalling: a complex web in cancer progression
Ikushima, Hiroaki and Miyazono, Kohei
Nature Reviews Cancer 10 415 - 424
doi: 10.1038/nrc2853Regulation of miRNA expression by Src and contact normalization: effects on nonanchored cell growth and migration
Li, X et al.
Oncogene 28 4272 - 4283
(21 September 2009); doi: 10.1038/onc.2009.278Anchorage of VEGF to the extracellular matrix conveys differential signaling responses to endothelial cells
Chen, T. T. et al.
The Journal of Cell Biology 188
(22 February 2010); doi: 10.1083/jcb.200906044Id2 Promotes Tumor Cell Migration and Invasion through Transcriptional Repression of Semaphorin 3F
Coma, S. et al.
Cancer Research 70
(1 May 2010); doi: 10.1158/0008-5472.CAN-09-3048The RhoA Activator GEF-H1/Lfc Is a Transforming Growth Factor- Target Gene and Effector That Regulates -Smooth Muscle Actin Expression and Cell Migration
Tsapara, A. et al.
Molecular Biology of the Cell 21
(15 March 2010); doi: 10.1091/mbc.E09-07-0567WNT11 Expression Is Induced by Estrogen-Related Receptor and -Catenin and Acts in an Autocrine Manner to Increase Cancer Cell Migration
Dwyer, M. A. et al.
Cancer Research 70
(15 November 2010); doi: 10.1158/0008-5472.CAN-10-0226Differential Regulation of Protrusion and Polarity by PI(3)K during Neutrophil Motility in Live Zebrafish
Yoo, Sa Kan et al.
Developmental Cell 18
(16 February 2010); doi: 10.1016/j.devcel.2009.11.015miR-200bc/429 cluster targets PLCγ1 and differentially regulates proliferation and EGF-driven invasion than miR-200a/141 in breast cancer
Uhlmann, S et al.
Oncogene 29 4297 - 4306
(31 May 2010); doi: 10.1038/onc.2010.201The Tight Junction Protein, Occludin, Regulates the Directional Migration of Epithelial Cells
Du, Dan et al.
Developmental Cell 18
(19 January 2010); doi: 10.1016/j.devcel.2009.12.008Cadherins and Pak1 Control Contact Inhibition of Proliferation by Pak1- PIX-GIT Complex-Dependent Regulation of Cell-Matrix Signaling
Liu, F. et al.
Molecular and Cellular Biology 30
(15 April 2010); doi: 10.1128/MCB.01247-09PLEKHA7 Is an Adherens Junction Protein with a Tissue Distribution and Subcellular Localization Distinct from ZO-1 and E-Cadherin
Pulimeno, Pamela et al.
PLoS ONE 5
(20 August 2010); doi: 10.1371/journal.pone.0012207Integrins in cancer: biological implications and therapeutic opportunities
Desgrosellier, Jay S. and Cheresh, David A.
Nature Reviews Cancer 10 9 - 22
doi: 10.1038/nrc2748Different Effects of Angiotensin II and Angiotensin-(1-7) on Vascular Smooth Muscle Cell Proliferation and Migration
Zhang, Feng et al.
PLoS ONE 5
(23 August 2010); doi: 10.1371/journal.pone.0012323Directional Persistence of Cell Migration Coincides with Stability of Asymmetric Intracellular Signaling CMC
Weiger, Michael C., Ahmed, Shoeb, Welf, Erik S. and Haugh, Jason M.
Biophysical Journal 98
(6 January 2010); doi: 10.1016/j.bpj.2009.09.051Stochastic Model of Integrin-Mediated Signaling and Adhesion Dynamics at the Leading Edges of Migrating Cells CMC
Cirit, Murat et al.
PLoS Computational Biology 6
(26 February 2010); doi: 10.1371/journal.pcbi.1000688Keratin 8/18 Modulation of Protein Kinase C-mediated Integrin-dependent Adhesion and Migration of Liver Epithelial Cells
Bordeleau, F. et al.
Molecular Biology of the Cell 21
(15 May 2010); doi: 10.1091/mbc.E09-05-0373From the Cover: Ancient origin of the integrin-mediated adhesion and signaling machinery
Sebe-pedros, A. et al.
Proceedings of the National Academy of Sciences 107
(1 June 2010); doi: 10.1073/pnas.1002257107Mechano-Chemical Feedbacks Regulate Actin Mesh Growth in Lamellipodial Protrusions
Hu, Longhua and Papoian, Garegin A.
Biophysical Journal 98
(21 April 2010); doi: 10.1016/j.bpj.2009.11.054Inside-Out Regulation of L1 Conformation, Integrin Binding, Proteolysis, and Concomitant Cell Migration
Chen, M. M. et al.
Molecular Biology of the Cell 21
(15 May 2010); doi: 10.1091/mbc.E09-10-0900The FERM domain: organizing the structure and function of FAK
Frame, Margaret C. et al.
Nature Reviews Molecular Cell Biology 11 802 - 814
(22 October 2010); doi: 10.1038/nrm2996Mechanisms guiding primordial germ cell migration: strategies from different organisms
Richardson, Brian E. and Lehmann, Ruth
Nature Reviews Molecular Cell Biology 11 37 - 49
doi: 10.1038/nrm2815Dpp Signaling Directs Cell Motility and Invasiveness during Epithelial Morphogenesis
Ninov, Nikolay et al.
Current Biology 20
(23 March 2010); doi: 10.1016/j.cub.2010.01.063A Ras Signaling Complex Controls the RasC-TORC2 Pathway and Directed Cell Migration
Charest, Pascale G. et al.
Developmental Cell 18
(18 May 2010); doi: 10.1016/j.devcel.2010.03.017Src Cannot Break Barriers Alone : Src-induced Tyrosine Phosphorylation of VE-cadherin Is Not Sufficient to Decrease Barrier Function of Endothelial Monolayers
Journal of Biological Chemistry 285
(5 March 2010); doi: 10.1074/jbc.P109.079277Dynamics and Mechanism of p130Cas Localization to Focal Adhesions
Donato, D. M. et al.
Journal of Biological Chemistry 285
(2 July 2010); doi: 10.1074/jbc.M109.091207Actin and serum response factor transduce physical cues from the microenvironment to regulate epidermal stem cell fate decisions
Connelly, John T. et al.
Nature Cell Biology 12 711 - 718
(27 June 2010); doi: 10.1038/ncb2074Bacterial motility complexes require the actin-like protein, MreB and the Ras homologue, MglA
Mauriello, Emilia M F et al.
The EMBO Journal 29 315 - 326
(3 December 2009); doi: 10.1038/emboj.2009.356The PAR complex regulates pulsed actomyosin contractions during amnioserosa apical constriction in Drosophila
David, D. J. V., Tishkina, A. and Harris, T. J. C.
Development 137
(15 May 2010); doi: 10.1242/dev.044107Modulation of Cellular Migration and Survival by c-Myc through the Downregulation of Urokinase (uPA) and uPA Receptor
Alfano, D. et al.
Molecular and Cellular Biology 30
(1 April 2010); doi: 10.1128/MCB.01442-09Activation of EGFR on monocytes is required for human cytomegalovirus entry and mediates cellular motility
Chan, G., Nogalski, M. T. and Yurochko, A. D.
Proceedings of the National Academy of Sciences 106
(29 December 2009); doi: 10.1073/pnas.0908787106Apoptotic Cells Activate the "Phoenix Rising" Pathway to Promote Wound Healing and Tissue Regeneration
Li, F. et al.
Science Signaling 3
(23 February 2010); doi: 10.1126/scisignal.2000634Mutant p53 Drives Invasion by Promoting Integrin Recycling
Muller, Patricia A.J. et al.
Cell 139
(24 December 2009); doi: 10.1016/j.cell.2009.11.026Bax Inhibitor 1 Increases Cell Adhesion through Actin Polymerization: Involvement of Calcium and Actin Binding
Lee, G.-H. et al.
Molecular and Cellular Biology 30
(1 April 2010); doi: 10.1128/MCB.01357-09Photorhabdus luminescens Toxins ADP-Ribosylate Actin and RhoA to Force Actin Clustering
Lang, A. E. et al.
Science 327
(26 February 2010); doi: 10.1126/science.1184557PDK1 Regulates Vascular Remodeling and Promotes Epithelial-Mesenchymal Transition in Cardiac Development
Feng, Q. et al.
Molecular and Cellular Biology 30
(15 July 2010); doi: 10.1128/MCB.00420-10Rho-Kinase Directs Bazooka/Par-3 Planar Polarity during Drosophila Axis Elongation
Simões, Sérgio de Matos et al.
Developmental Cell 19
(14 September 2010); doi: 10.1016/j.devcel.2010.08.011Integrins and Mutant p53 on the Road to Metastasis
Selivanova, Galina and Ivaska, Johanna
Cell 139
(24 December 2009); doi: 10.1016/j.cell.2009.12.016Phosphorylation of paxillin at threonine 538 by PKC regulates LFA1-mediated adhesion of lymphoid cells
Romanova, L. Y. et al.
Journal of Cell Science 123
(1 May 2010); doi: 10.1242/jcs.060996OSVZ progenitors of human and ferret neocortex are epithelial-like and expand by integrin signaling
Fietz, Simone A et al.
Nature Neuroscience 13 690 - 699
(2 May 2010); doi: 10.1038/nn.2553Oncogenic Src requires a wild-type counterpart to regulate invadopodia maturation
Kelley, L. C. et al.
Journal of Cell Science 123
(15 November 2010); doi: 10.1242/jcs.075200A Complex between FAK, RACK1, and PDE4D5 Controls Spreading Initiation and Cancer Cell Polarity
Serrels, Bryan et al.
Current Biology 20
(22 June 2010); doi: 10.1016/j.cub.2010.04.042Lipid Phosphate Phosphatase 3 Stabilization of -Catenin Induces Endothelial Cell Migration and Formation of Branching Point Structures
Humtsoe, J. O., Liu, M., Malik, A. B. and Wary, K. K.
Molecular and Cellular Biology 30
(1 April 2010); doi: 10.1128/MCB.00038-09CRL2LRR-1 Targets a CDK Inhibitor for Cell Cycle Control in C. elegans and Actin-Based Motility Regulation in Human Cells
Starostina, Natalia G., Simpliciano, Jennifer M., Mcguirk, Michael A. and Kipreos, Edward T.
Developmental Cell 19
(16 November 2010); doi: 10.1016/j.devcel.2010.10.013Merlin/NF2 Suppresses Tumorigenesis by Inhibiting the E3 Ubiquitin Ligase CRL4DCAF1 in the Nucleus
Li, Wei et al.
Cell 140
(19 February 2010); doi: 10.1016/j.cell.2010.01.029Suppression of Integrin 3 1 in Breast Cancer Cells Reduces Cyclooxygenase-2 Gene Expression and Inhibits Tumorigenesis, Invasion, and Cross-Talk to Endothelial Cells
Mitchell, K. et al.
Cancer Research 70
(1 August 2010); doi: 10.1158/0008-5472.CAN-09-4283Analysis of integrin turnover in fly myotendinous junctions
Yuan, L., Fairchild, M. J., Perkins, A. D. and Tanentzapf, G.
Journal of Cell Science 123
(15 March 2010); doi: 10.1242/jcs.063040Clathrin-independent carriers form a high capacity endocytic sorting system at the leading edge of migrating cells
Howes, M. T. et al.
The Journal of Cell Biology 190
(23 August 2010); doi: 10.1083/jcb.201002119The tumor-associated EpCAM regulates morphogenetic movements through intracellular signaling
Maghzal, N. et al.
The Journal of Cell Biology 191
(1 November 2010); doi: 10.1083/jcb.201004074Phosphoinositides Are Essential Coactivators for p21-Activated Kinase 1
Strochlic, Todd I. et al.
Molecular Cell 40
(12 November 2010); doi: 10.1016/j.molcel.2010.10.015MYC regulation of a "poor-prognosis" metastatic cancer cell state
Wolfer, A. et al.
Proceedings of the National Academy of Sciences 107
(23 February 2010); doi: 10.1073/pnas.0914203107Astn2, A Novel Member of the Astrotactin Gene Family, Regulates the Trafficking of ASTN1 during Glial-Guided Neuronal Migration
Wilson, P. M., Fryer, R. H., Fang, Y. and Hatten, M. E.
Journal of Neuroscience 30
(23 June 2010); doi: 10.1523/JNEUROSCI.0032-10.2010Integrin-Induced PIP5K1C Kinase Polarization Regulates Neutrophil Polarization, Directionality, and In Vivo Infiltration
Xu, Wenwen et al.
Immunity 33
(24 September 2010); doi: 10.1016/j.immuni.2010.08.015Interaction with surrounding normal epithelial cells influences signalling pathways and behaviour of Src-transformed cells
Kajita, M. et al.
Journal of Cell Science 123
(15 January 2010); doi: 10.1242/jcs.057976Active Mek2 as a regulatory scaffold that promotes Pin1 binding to BPGAP1 to suppress BPGAP1-induced acute Erk activation and cell migration
Pan, C. Q., Liou, Y.-c. and Low, B. C.
Journal of Cell Science 123
(15 March 2010); doi: 10.1242/jcs.064162Light-mediated activation reveals a key role for Rac in collective guidance of cell movement in vivo CMC
Wang, Xiaobo et al.
Nature Cell Biology 12 591 - 597
(16 May 2010); doi: 10.1038/ncb2061Coordinated RhoA signaling at the leading edge and uropod is required for T cell transendothelial migration
Heasman, S. J. et al.
The Journal of Cell Biology 190
(23 August 2010); doi: 10.1083/jcb.201002067Tuberous Sclerosis Complex 2 (TSC2) Regulates Cell Migration and Polarity through Activation of CDC42 and RAC1
Larson, Y. et al.
Journal of Biological Chemistry 285
(6 August 2010); doi: 10.1074/jbc.M109.096917A role for Rho GTPases and cell–cell adhesion in single-cell motility in vivo
Kardash, Elena et al.
Nature Cell Biology 12 47 - 53
(13 December 2009); doi: 10.1038/ncb2003An Evolutionarily Conserved Autoinhibitory Molecular Switch in ELMO Proteins Regulates Rac Signaling
Patel, Manishha et al.
Current Biology 20
(23 November 2010); doi: 10.1016/j.cub.2010.10.028Spontaneous assembly and active disassembly balance adherens junction homeostasis
Hong, S., Troyanovsky, R. B. and Troyanovsky, S. M.
Proceedings of the National Academy of Sciences 107
(23 February 2010); doi: 10.1073/pnas.0911027107Head of Myosin IX Binds Calmodulin and Moves Processively toward the Plus-end of Actin Filaments
Liao, W., Elfrink, K. and Bahler, M.
Journal of Biological Chemistry 285
(6 August 2010); doi: 10.1074/jbc.M110.101105Migration or evasion
Melief, Cornelis
Nature Medicine 16 35 - 36
doi: 10.1038/nm0110-35Optimal Germinal Center Responses Require a Multistage T Cell:B Cell Adhesion Process Involving Integrins, SLAM-Associated Protein, and CD84
Cannons, Jennifer L. et al.
Immunity 32
(26 February 2010); doi: 10.1016/j.immuni.2010.01.010Specific tyrosine phosphorylation sites on cortactin regulate Nck1-dependent actin polymerization in invadopodia CMC
Oser, M. et al.
Journal of Cell Science 123
(1 November 2010); doi: 10.1242/jcs.068163A genome-wide RNAi screen identifies multiple RSK-dependent regulators of cell migration
Smolen, G. A. et al.
Genes & Development
(9 November 2010); doi: 10.1101/gad.1989110Her2 activates NF-κB and induces invasion through the canonical pathway involving IKKα
Merkhofer, E C, Cogswell, P and Baldwin, A S
Oncogene 29 1238 - 1248
(30 November 2009); doi: 10.1038/onc.2009.410Src-dependent phosphorylation of ROCK participates in regulation of focal adhesion dynamics
Lee, H.-H. et al.
Journal of Cell Science 123
(1 October 2010); doi: 10.1242/jcs.071555Type I PIPK- regulates directed cell migration by modulating Rac1 plasma membrane targeting and activation
Chao, W.-T., Daquinag, A. C., Ashcroft, F. and Kunz, J.
The Journal of Cell Biology 190
(26 July 2010); doi: 10.1083/jcb.200911110Interaction of Syndecan and 6 4 Integrin Cytoplasmic Domains: REGULATION OF ErbB2-MEDIATED INTEGRIN ACTIVATION
Wang, H., Leavitt, L., Ramaswamy, R. and Rapraeger, A. C.
Journal of Biological Chemistry 285
(30 April 2010); doi: 10.1074/jbc.M110.102137From the Cover: In vitro and in vivo reconstitution of the cadherin-catenin-actin complex from Caenorhabditis elegans
Kwiatkowski, A. V. et al.
Proceedings of the National Academy of Sciences 107
(17 August 2010); doi: 10.1073/pnas.1007349107YKL-40, a secreted glycoprotein, promotes tumor angiogenesis
Shao, R et al.
Oncogene 28 4456 - 4468
(21 September 2009); doi: 10.1038/onc.2009.292Competition amongst Eph receptors regulates contact inhibition of locomotion and invasiveness in prostate cancer cells
Astin, Jonathan W. et al.
Nature Cell Biology 12 1194 - 1204
(14 November 2010); doi: 10.1038/ncb2122JWA regulates melanoma metastasis by integrin αVβ3 signaling
Bai, J et al.
Oncogene 29 1227 - 1237
(30 November 2009); doi: 10.1038/onc.2009.408Chemotaxis: insights from the extending pseudopod
Van haastert, P. J. M.
Journal of Cell Science 123
(15 September 2010); doi: 10.1242/jcs.071118Integrins: masters and slaves of endocytic transport CMC
Caswell, Patrick T., Vadrevu, Suryakiran and Norman, Jim C.
Nature Reviews Molecular Cell Biology 10 843 - 853
doi: 10.1038/nrm2799Differential epidermal growth factor receptor signaling regulates anchorage-independent growth by modulation of the PI3K/AKT pathway
Humtsoe, J O and Kramer, R H
Oncogene 29 1214 - 1226
(23 November 2009); doi: 10.1038/onc.2009.419Mobility of G proteins is heterogeneous and polarized during chemotaxis
Van hemert, F., Lazova, M. D., Snaar-jagaska, B. E. and Schmidt, T.
Journal of Cell Science 123
(1 September 2010); doi: 10.1242/jcs.063990EphB-ephrin-B2 interactions are required for thymus migration during organogenesis
Foster, K. E. et al.
Proceedings of the National Academy of Sciences 107
(27 July 2010); doi: 10.1073/pnas.1003747107v 3 integrin spatially regulates VASP and RIAM to control adhesion dynamics and migration
Worth, D. C. et al.
The Journal of Cell Biology 189
(19 April 2010); doi: 10.1083/jcb.200912014The Actin-Bundling Protein L-Plastin Dissociates CCR7 Proximal Signaling from CCR7-Induced Motility
Morley, S. C. et al.
The Journal of Immunology 184
(1 April 2010); doi: 10.4049/jimmunol.0903851Tissue remodelling through branching morphogenesis CMC
Affolter, Markus, Zeller, Rolf and Caussinus, Emmanuel
Nature Reviews Molecular Cell Biology 10 831 - 842
doi: 10.1038/nrm2797Syndecan-1 couples the insulin-like growth factor-1 receptor to inside-out integrin activation
Beauvais, D. M. and Rapraeger, A. C.
Journal of Cell Science 123
(1 November 2010); doi: 10.1242/jcs.067645Integrin signalling adaptors: not only figurants in the cancer story
Cabodi, Sara, Del pilar camacho-leal, Maria, Di stefano, Paola and Defilippi, Paola
Nature Reviews Cancer 10 858 - 870
(24 November 2010); doi: 10.1038/nrc2967Phosphorylation of Leukocyte PECAM and Its Association with Detergent-Resistant Membranes Regulate Transendothelial Migration
Florey, O., Durgan, J. and Muller, W.
The Journal of Immunology 185
(1 August 2010); doi: 10.4049/jimmunol.1001305I-BAR protein antagonism of endocytosis mediates directional sensing during guided cell migration
Quinones, G. A., Jin, J. and Oro, A. E.
The Journal of Cell Biology 189
(19 April 2010); doi: 10.1083/jcb.200910136Focal Adhesion Kinase Is Required for Intestinal Regeneration and Tumorigenesis Downstream of Wnt/c-Myc Signaling
Ashton, Gabrielle H. et al.
Developmental Cell 19
(17 August 2010); doi: 10.1016/j.devcel.2010.07.015Ovo1 links Wnt signaling with N-cadherin localization during neural crest migration
Piloto, S. and Schilling, T. F.
Development 137
(15 June 2010); doi: 10.1242/dev.048439Ras-induced invasion and metastasis are regulated by a leukotriene B4 receptor BLT2-linked pathway
Kim, E-Y, Seo, J-M, Cho, K-J and Kim, J-H
Oncogene 29 1167 - 1178
(23 November 2009); doi: 10.1038/onc.2009.412An MEK-cofilin signalling module controls migration of human T cells in 3D but not 2D environments
Klemke, Martin et al.
The EMBO Journal 29 2915 - 2929
(30 July 2010); doi: 10.1038/emboj.2010.153ERα signaling through slug regulates E-cadherin and EMT
Ye, Y et al.
Oncogene 29 1451 - 1462
(18 January 2010); doi: 10.1038/onc.2009.433E-catenin regulates actin dynamics independently of cadherin-mediated cell-cell adhesion
Benjamin, J. M. et al.
The Journal of Cell Biology 189
(19 April 2010); doi: 10.1083/jcb.200910041p53-Mediated transactivation of LIMK2b links actin dynamics to cell cycle checkpoint control
Hsu, F-F, Lin, T-Y, Chen, J-Y and Shieh, S-Y
Oncogene 29 2864 - 2876
(1 March 2010); doi: 10.1038/onc.2010.40Focal-adhesion targeting links caveolin-1 to a Rac1-degradation pathway
Nethe, M. et al.
Journal of Cell Science 123
(1 June 2010); doi: 10.1242/jcs.062919T Cell Receptor “Inside-Out” Pathway via Signaling Module SKAP1-RapL Regulates T Cell Motility and Interactions in Lymph Nodes
Raab, Monika et al.
Immunity 32
(23 April 2010); doi: 10.1016/j.immuni.2010.03.007Integrins stimulate E-cadherin-mediated intercellular adhesion by regulating Src-kinase activation and actomyosin contractility
Martinez-rico, C., Pincet, F., Thiery, J.-P. and Dufour, S.
Journal of Cell Science 123
(1 March 2010); doi: 10.1242/jcs.047878Stochastic Dynamics of Membrane Protrusion Mediated by the DOCK180/Rac Pathway in Migrating Cells CMC
Welf, Erik S. and Haugh, Jason M.
Cellular and Molecular Bioengineering 3
(6 March 2010); doi: 10.1007/s12195-010-0100-8Plakoglobin regulates cell motility through Rho- and fibronectin-dependent Src signaling
Todorovic, V. et al.
Journal of Cell Science 123
(15 October 2010); doi: 10.1242/jcs.070391The Protein Kinase C Cascade Regulates Recruitment of Matrix Metalloprotease 9 to Podosomes and Its Release and Activation
Xiao, H. et al.
Molecular and Cellular Biology 30
(1 December 2010); doi: 10.1128/MCB.00382-10mDia1 Targets v-Src to the Cell Periphery and Facilitates Cell Transformation, Tumorigenesis, and Invasion
Tanji, M. et al.
Molecular and Cellular Biology 30
(1 October 2010); doi: 10.1128/MCB.00197-10Cadherin 6B induces BMP signaling and de-epithelialization during the epithelial mesenchymal transition of the neural crest
Park, K.-S. and Gumbiner, B. M.
Development 137
(15 August 2010); doi: 10.1242/dev.050096VEGFR2 (KDR/Flk1) Signaling Mediates Axon Growth in Response to Semaphorin 3E in the Developing Brain
Bellon, Anaïs et al.
Neuron 66
(29 April 2010); doi: 10.1016/j.neuron.2010.04.006Polarity proteins and Rho GTPases cooperate to spatially organise epithelial actin-based protrusions
Georgiou, M. and Baum, B.
Journal of Cell Science 123
(1 April 2010); doi: 10.1242/jcs.060772The Adaptor Protein TRIP6 Antagonizes Fas-Induced Apoptosis but Promotes Its Effect on Cell Migration
Lai, Y.-J. et al.
Molecular and Cellular Biology 30
(1 December 2010); doi: 10.1128/MCB.00134-10Integrin-mediated Cell Attachment Induces a PAK4-dependent Feedback Loop Regulating Cell Adhesion through Modified Integrin v 5 Clustering and Turnover
Li, Z. et al.
Molecular Biology of the Cell 21
(1 October 2010); doi: 10.1091/mbc.E10-03-0245Ubiquitination of α5β1 Integrin Controls Fibroblast Migration through Lysosomal Degradation of Fibronectin-Integrin Complexes
Lobert, Viola Hélène et al.
Developmental Cell 19
(20 July 2010); doi: 10.1016/j.devcel.2010.06.010G Protein Subunit G 13 Binds to Integrin IIb 3 and Mediates Integrin "Outside-In" Signaling
Gong, H. et al.
Science 327
(15 January 2010); doi: 10.1126/science.1174779Polarization and Migration of Hematopoietic Stem and Progenitor Cells Rely on the RhoA/ROCK I Pathway and an Active Reorganization of the Microtubule Network
Fonseca, A.-V., Freund, D., Bornhauser, M. and Corbeil, D.
Journal of Biological Chemistry 285
(8 October 2010); doi: 10.1074/jbc.M110.145037Dynamic regulation of ROCK in tumor cells controls CXCR4-driven adhesion events
Struckhoff, A. P. et al.
Journal of Cell Science 123
(1 February 2010); doi: 10.1242/jcs.052167VEGF receptor 2/-3 heterodimers detected in situ by proximity ligation on angiogenic sprouts
Nilsson, Ingrid et al.
The EMBO Journal 29 1377 - 1388
(11 March 2010); doi: 10.1038/emboj.2010.30p21-activated kinase 4 regulates ovarian cancer cell proliferation, migration, and invasion and contributes to poor prognosis in patients
Siu, M. K. Y. et al.
Proceedings of the National Academy of Sciences 107
(26 October 2010); doi: 10.1073/pnas.0907481107Eicosanoids and cancer
Wang, Dingzhi and Dubois, Raymond N.
Nature Reviews Cancer 10 181 - 193
(19 February 2010); doi: 10.1038/nrc2809WASH and WAVE actin regulators of the Wiskott-Aldrich syndrome protein (WASP) family are controlled by analogous structurally related complexes
Jia, D. et al.
Proceedings of the National Academy of Sciences 107
(8 June 2010); doi: 10.1073/pnas.0913293107Prostaglandin E2/EP1 Signaling Pathway Enhances Intercellular Adhesion Molecule 1 (ICAM-1) Expression and Cell Motility in Oral Cancer Cells
Yang, S.-F. et al.
Journal of Biological Chemistry 285
(24 September 2010); doi: 10.1074/jbc.M110.108183Vang-like protein 2 and Rac1 interact to regulate adherens junctions
Lindqvist, M. et al.
Journal of Cell Science 123
(1 February 2010); doi: 10.1242/jcs.048074Interleukin-6 induces increased motility, cell–cell and cell–substrate dyshesion and epithelial-to-mesenchymal transformation in breast cancer cells
Sehgal, P B
Oncogene 29 2599 - 2600
(8 February 2010); doi: 10.1038/onc.2010.4Regulation of NOTCH signaling by reciprocal inhibition of HES1 and Deltex 1 and its role in osteosarcoma invasiveness
Zhang, P et al.
Oncogene 29 2916 - 2926
(8 March 2010); doi: 10.1038/onc.2010.62Endosomal-sorting complexes required for transport (ESCRT) pathway-dependent endosomal traffic regulates the localization of active Src at focal adhesions
Tu, C. et al.
Proceedings of the National Academy of Sciences 107
(14 September 2010); doi: 10.1073/pnas.1009471107The Salmonella SPI2 Effector SseI Mediates Long-Term Systemic Infection by Modulating Host Cell Migration
Mclaughlin, Laura M. et al.
PLoS Pathogens 5
(26 November 2009); doi: 10.1371/journal.ppat.1000671miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis
Ma, Li et al.
Nature Cell Biology 12 247 - 256
(21 February 2010); doi: 10.1038/ncb2024CAV1 Inhibits Metastatic Potential in Melanomas through Suppression of the Integrin/Src/FAK Signaling Pathway
Trimmer, C. et al.
Cancer Research 70
(1 October 2010); doi: 10.1158/0008-5472.CAN-10-0900FAK-mediated extracellular signals are essential for interkinetic nuclear migration and planar divisions in the neuroepithelium
Tsuda, S. et al.
Journal of Cell Science 123
(1 February 2010); doi: 10.1242/jcs.057851The final steps of integrin activation: the end game
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Nature Reviews Molecular Cell Biology 11 288 - 300
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