Subject archive
2006 Signalling
GIT2 represses Crk- and Rac1-regulated cell spreading and Cdc42-mediated focal adhesion turnover
Frank, Scott R, Adelstein, Molly R and Hansen, Steen H
The EMBO Journal 25
(4 September 0007); doi: 10.1038/sj.emboj.7601092Semaphorin 4D/Plexin-B1-mediated R-Ras GAP activity inhibits cell migration by regulating 1 integrin activity
Oinuma, I.
The Journal of Cell Biology 173
(22 May 2006); doi: 10.1083/jcb.200508204RLIP76 (RalBP1) is an R-Ras effector that mediates adhesion-dependent Rac activation and cell migration CMC
Goldfinger, L. E.
The Journal of Cell Biology 174
(5 September 2006); doi: 10.1083/jcb.200603111Integrin-induced Tyrosine Phosphorylation of Protein-tyrosine Phosphatase- Is Required for Cytoskeletal Reorganization and Cell Migration
Chen, M.
Journal of Biological Chemistry 281
(26 January 2006); doi: 10.1074/jbc.M600561200An Interaction between Insulin-like Growth Factor-binding Protein 2 (IGFBP2) and Integrin 5 Is Essential for IGFBP2-induced Cell Mobility
Wang, G. K.
Journal of Biological Chemistry 281
(17 February 2006); doi: 10.1074/jbc.M513686200CAP interacts with cytoskeletal proteins and regulates adhesion-mediated ERK activation and motility
doi: 10.1038/sj.emboj.7601406The Rac activator Tiam1 is required for 3 1-mediated laminin-5 deposition, cell spreading, and cell migration
Hamelers, I. H.L.
The Journal of Cell Biology 171
(5 December 2005); doi: 10.1083/jcb.200509172Integrin 2-mediated ERK and Calpain Activation Play a Critical Role in Cell Adhesion and Motility via Focal Adhesion Kinase Signaling: IDENTIFICATION OF A NOVEL SIGNALING PATHWAY
Sawhney, R. S.
Journal of Biological Chemistry 281
(7 February 2006); doi: 10.1074/jbc.M600787200VEGF receptor signalling — in control of vascular function
Olsson, Anna-Karin, Dimberg, Anna, Kreuger, Johan and Claesson-welsh, Lena
Nature Reviews Molecular Cell Biology 7 359 - 371
doi: 10.1038/nrm1911PKC -dependent activation of RhoA by syndecan-4 during focal adhesion formation
Dovas, A.
Journal of Cell Science 119
(6 June 2006); doi: 10.1242/jcs.03020MDM2 Promotes Cell Motility and Invasiveness by Regulating E-Cadherin Degradation
Yang, J.-Y.
Molecular and Cellular Biology 26
(1 October 2006); doi: 10.1128/MCB.00172-06Glycogen Synthase Kinase 3 and h-prune Regulate Cell Migration by Modulating Focal Adhesions
Kobayashi, T.
Molecular and Cellular Biology 26
(1 February 2006); doi: 10.1128/MCB.26.3.898-911.2006Src SH2 Arginine 175 Is Required for Cell Motility: Specific Focal Adhesion Kinase Targeting and Focal Adhesion Assembly Function
Yeo, M. G.
Molecular and Cellular Biology 26
(15 June 2006); doi: 10.1128/MCB.01147-05CdGAP Associates with Actopaxin to Regulate Integrin-Dependent Changes in Cell Morphology and Motility
Lalonde, D, Grubinger, M, Lamarchevane, N and Turner, C
Current Biology 16
(25 July 2006); doi: 10.1016/j.cub.2006.05.057Caspase-3-dependent Activation of Calcium-independent Phospholipase A2 Enhances Cell Migration in Non-apoptotic Ovarian Cancer Cells
Zhao, X.
Journal of Biological Chemistry 281
(7 August 2006); doi: 10.1074/jbc.M513105200Ras-Associated Protein-1 Regulates Extracellular Signal-Regulated Kinase Activation and Migration in Melanoma Cells: Two Processes Important to Melanoma Tumorigenesis and Metastasis
Cancer Research
PKCϵ-mediated phosphorylation of vimentin controls integrin recycling and motility
doi: 10.1038/sj.emboj.7600847An Uncleavable uPAR Mutant Allows Dissection of Signaling Pathways in uPA-dependent Cell Migration
Mazzieri, R.
Molecular Biology of the Cell 17
(2 November 2005); doi: 10.1091/mbc.E05-07-0635MAPKAPK-2-mediated LIM-kinase activation is critical for VEGF-induced actin remodeling and cell migration
Kobayashi, Miho et al.
The EMBO Journal 25
(22 October 0007); doi: 10.1038/sj.emboj.7600973Regulation of Cell Adhesion by Protein-tyrosine Phosphatases: I. CELL-MATRIX ADHESION
Burridge, K.
Journal of Biological Chemistry 281
(11 April 2006); doi: 10.1074/jbc.R500030200Phosphorylation of Tyr1214 within VEGFR-2 Triggers the Recruitment of Nck and Activation of Fyn Leading to SAPK2/p38 Activation and Endothelial Cell Migration in Response to VEGF
Lamalice, L., Houle, F. and Huot, J.
Journal of Biological Chemistry 281
(7 August 2006); doi: 10.1074/jbc.M6039282005-Hydroxytryptamine Induces Mast Cell Adhesion and Migration
J Immunol
Involvement of Src Family Kinases in N-Cadherin Phosphorylation and beta-Catenin Dissociation during Transendothelial Migration of Melanoma Cells
Qi, J.
Molecular Biology of the Cell 17
(21 December 2005); doi: 10.1091/mbc.E05-10-0927The activity status of cofilin is directly related to invasion, intravasation, and metastasis of mammary tumors
Wang, W.
The Journal of Cell Biology 173
(8 May 2006); doi: 10.1083/jcb.200510115Regulation of Cell Adhesion by Protein-tyrosine Phosphatases: II. CELL-CELL ADHESION
Sallee, J. L.
Journal of Biological Chemistry 281
(13 March 2006); doi: 10.1074/jbc.R600003200Plectin-controlled keratin cytoarchitecture affects MAP kinases involved in cellular stress response and migration
Osmanagic-myers, S.
The Journal of Cell Biology 174
(7 August 2006); doi: 10.1083/jcb.200605172Suppression of Cancer Cell Migration and Invasion by Protein Phosphatase 2A through Dephosphorylation of - and m-Calpains
Xu, L. and Deng, X.
Journal of Biological Chemistry 281
(12 September 2006); doi: 10.1074/jbc.M607702200Cancer Res
Endothelial Cell Cortactin Coordinates Intercellular Adhesion Molecule-1 Clustering and Actin Cytoskeleton Remodeling during Polymorphonuclear Leukocyte Adhesion and Transmigration
J Immunol
Phospholipase D Couples Survival and Migration Signals in Stress Response of Human Cancer Cells
Zheng, Y.
Journal of Biological Chemistry 281
(11 April 2006); doi: 10.1074/jbc.M600660200N-Cadherin and Keratinocyte Growth Factor Receptor Mediate the Functional Interplay between Ki-RASG12V and p53V143A in Promoting Pancreatic Cell Migration, Invasion, and Tissue Architecture Disruption
Deramaudt, T. B.
Molecular and Cellular Biology 26
(1 June 2006); doi: 10.1128/MCB.01055-05Interaction of Phospholipase C- 1 with Villin Regulates Epithelial Cell Migration
Tomar, A. et al.
Journal of Biological Chemistry 281
(24 August 2006); doi: 10.1074/jbc.M604323200Expression of Wnt-5a Is Correlated with Aggressiveness of Gastric Cancer by Stimulating Cell Migration and Invasion
Kurayoshi, M. et al.
Cancer Research 66
(1 November 2006); doi: 10.1158/0008-5472.CAN-06-2359The Shed Ectodomain of Nr-CAM Stimulates Cell Proliferation and Motility, and Confers Cell Transformation
Cancer Res
Ephrin-B2 Controls Cell Motility and Adhesion during Blood-Vessel-Wall Assembly
Cell
Src Uses Cas to Suppress Fhl1 in Order to Promote Nonanchored Growth and Migration of Tumor Cells
Shen, Y.
Cancer Research 66
(1 February 2006); doi: 10.1158/0008-5472.CAN-05-3152Emodin Inhibits Tumor Cell Adhesion through Disruption of the Membrane Lipid Raft-Associated Integrin Signaling Pathway
Huang, Q.
Cancer Research 66
(1 June 2006); doi: 10.1158/0008-5472.CAN-06-0077Identification of a receptor necessary for Nogo-B stimulated chemotaxis and morphogenesis of endothelial cells
Miao, R. Q.
Proceedings of the National Academy of Sciences 103
(10 July 2006); doi: 10.1073/pnas.0602427103Spatial and Temporal Control of Cofilin Activity Is Required for Directional Sensing during Chemotaxis
Mouneimne, G et al.
Current Biology 16
(21 November 2006); doi: 10.1016/j.cub.2006.09.016CD155/PVR Enhances Glioma Cell Dispersal by Regulating Adhesion Signaling and Focal Adhesion Dynamics
Cancer Res
Epidermal Growth Factor Receptor Overexpression Results in Increased Tumor Cell Motility In vivo Coordinately with Enhanced Intravasation and Metastasis
Cancer Res
Epidermal Growth Factor Induces Insulin Receptor Substrate-2 in Breast Cancer Cells via c-Jun NH2-Terminal Kinase/Activator Protein-1 Signaling to Regulate Cell Migration
Cancer Research
Growth and Motility Inhibition of Breast Cancer Cells by Epidermal Growth Factor Receptor Degradation Is Correlated with Inactivation of Cdc42
Hirsch, D. S.
Cancer Research 66
(1 April 2006); doi: 10.1158/0008-5472.CAN-05-1547Directional sensing in eukaryotic chemotaxis: A balanced inactivation model
Levine, H.
Proceedings of the National Academy of Sciences 103
(19 June 2006); doi: 10.1073/pnas.0601302103Mannose receptor regulates myoblast motility and muscle growth
Jansen, K. M.
The Journal of Cell Biology 174
(31 July 2006); doi: 10.1083/jcb.200601102Influx of extracellular Ca2+ is necessary for electrotaxis in Dictyostelium
Shanley, L. J. et al.
Journal of Cell Science 119
(24 October 2006); doi: 10.1242/jcs.03248Integrin aIIb
3 Induces the Adhesion and Activation of Mast Cells through Interaction with FibrinogenJ Immunol
Cyclooxygenase-1-derived PGE2 promotes cell motility via the G-protein-coupled EP4 receptor during vertebrate gastrulation
GENES & DEVELOPMENT
Exo70 interacts with the Arp2/3 complex and regulates cell migration
Zuo, Xiaofeng et al.
Nature Cell Biology 8 1383 - 1388
(5 November 2006); doi: 10.1038/ncb1505A Role for TLRs in the Regulation of Immune Cell Migration by First Trimester Trophoblast Cells
J Immunol
CD27 Dissects Mature NK Cells into Two Subsets with Distinct Responsiveness and Migratory Capacity
J Immunol
PRL Tyrosine Phosphatases Regulate Rho Family GTPases to Promote Invasion and Motility
Fiordalisi, J. J.
Cancer Research 66
(15 March 2006); doi: 10.1158/0008-5472.CAN-05-3116Synaptopodin orchestrates actin organization and cell motility via regulation of RhoA signalling
Asanuma, Katsuhiko et al.
Nature Cell Biology 8 485 - 491
(16 April 2006); doi: 10.1038/ncb1400Neuronal polarity is regulated by glycogen synthase kinase-3 (GSK-3 ) independently of Akt/PKB serine phosphorylation
Gartner, A.
Journal of Cell Science 119
(1 October 2006); doi: 10.1242/jcs.03159CD4+ T Cell Responses Elicited by Different Subsets of Human Skin Migratory Dendritic Cells
J Immunol
Prostaglandin E2 Is Generally Required for Human Dendritic Cell Migration and Exerts Its Effect via EP2 and EP4 Receptors
J Immunol
A Complex of Wiskott-Aldrich Syndrome Protein with Mammalian Verprolins Plays an Important Role in Monocyte Chemotaxis
J Immunol
DOCK2 is a Rac activator that regulates motility and polarity during neutrophil chemotaxis
Kunisaki, Y.
The Journal of Cell Biology 174
(28 August 2006); doi: 10.1083/jcb.200602142Silencing profilin-1 inhibits endothelial cell proliferation, migration and cord morphogenesis
Ding, Z.
Journal of Cell Science 119
(1 October 2006); doi: 10.1242/jcs.03178Phosphoinositides in cell regulation and membrane dynamics
Di paolo, Gilbert and De camilli, Pietro
Nature 443 651 - 657
doi: 10.1038/nature05185doublecortin-like kinase Functions with doublecortin to Mediate Fiber Tract Decussation and Neuronal Migration
Neuron
Tumor invasion in the absence of epithelial-mesenchymal transition: Podoplanin-mediated remodeling of the actin cytoskeleton
Cancer Cell
VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche
Kaplan, Rosandra N. et al.
Nature 438 820 - 827
doi: 10.1038/nature04186Genetic Interactions between Doublecortin and Doublecortin-like Kinase in Neuronal Migration and Axon Outgrowth
Neuron
Novel Function of IFN-?: Negative Regulation of Dendritic Cell Migration and T Cell Priming.
J Immunol.
G12/G13 Family G Proteins Regulate Marginal Zone B Cell Maturation, Migration, and Polarization
J Immunol
JNK- and Fos-regulated Mmp1 expression cooperates with Ras to induce invasive tumors in Drosophila
doi: 10.1038/sj.emboj.7601401Galectin-1-matured human monocyte-derived dendritic cells have enhanced migration through extracellular matrix
J Immunol.
2-chimaerin provides a diacylglycerol-dependent mechanism for regulation of adhesion and chemotaxis of T cells
Siliceo, M.
Journal of Cell Science 119
(1 January 2006); doi: 10.1242/jcs.02722Diffusion-limited phase separation in eukaryotic chemotaxis CMC
Gamba, A.
Proceedings of the National Academy of Sciences 102
(22 November 2005); doi: 10.1073/pnas.0503974102The small GTPase R-Ras regulates organization of actin and drives membrane protrusions through the activity of PLC
Ada-nguema, A. S.
Journal of Cell Science 119
(1 April 2006); doi: 10.1242/jcs.02835EphB Receptors Coordinate Migration and Proliferation in the Intestinal Stem Cell Niche
Holmberg, J et al.
Cell 125
(13 June 2006); doi: 10.1016/j.cell.2006.04.030beta4 Integrin and Epidermal Growth Factor Coordinately Regulate Electric Field-mediated Directional Migration via Rac1
Pullar, C. E. et al.
Molecular Biology of the Cell 17
(16 August 2006); doi: 10.1091/mbc.E06-05-0433Novel Approach to Inhibit Asthma-Mediated Lung Inflammation Using Anti-CD147 Intervention
The Journal of Immunology
Inhibition of calpain stabilises podosomes and impairs dendritic cell motility
Calle, Y.
Journal of Cell Science 119
(9 May 2006); doi: 10.1242/jcs.02939Electrical signals control wound healing through phosphatidylinositol-3-OH kinase-
and PTENZhao, Min et al.
Nature 442 457 - 460
doi: 10.1038/nature04925Extracellular Calpains Increase Tubular Epithelial Cell Mobility: IMPLICATIONS FOR KIDNEY REPAIR AFTER ISCHEMIA
Frangie, C.
Journal of Biological Chemistry 281
(6 June 2006); doi: 10.1074/jbc.M603007200Residual Antigen Presentation after Influenza Virus Infection Affects CD8 T Cell Activation and Migration
Immunity
Endocytic receptor LRP together with tPA and PAI-1 coordinates Mac-1-dependent macrophage migration
Cao, Chunzhang et al.
The EMBO Journal 25
(4 September 0007); doi: 10.1038/sj.emboj.7601082Ghrelin and the Growth Hormone Secretagogue Receptor Constitute a Novel Autocrine Pathway in Astrocytoma Motility
Dixit, V. D.
Journal of Biological Chemistry 281
(13 March 2006); doi: 10.1074/jbc.M600223200Cell Migration and Signaling Specificity Is Determined by the Phosphatidylserine Recognition Motif of Rac1
Finkielstein, C. V.
Journal of Biological Chemistry 281
(20 July 2006); doi: 10.1074/jbc.M605560200The Rho-mDia1 Pathway Regulates Cell Polarity and Focal Adhesion Turnover in Migrating Cells through Mobilizing Apc and c-Src
Yamana, N.
Molecular and Cellular Biology 26
(15 September 2006); doi: 10.1128/MCB.00283-06Macrophage Migration Inhibitory Factor Induces Macrophage Recruitment via CC Chemokine Ligand 2
J. Immunol
Effects of Peripheral Cannabinoid Receptor Ligands on Motility and Polarization in Neutrophil-like HL60 Cells and Human Neutrophils
Kurihara, R.
Journal of Biological Chemistry 281
(23 February 2006); doi: 10.1074/jbc.M510871200Caspase-8 Promotes Cell Motility and Calpain Activity under Nonapoptotic Conditions
Helfer, B.
Cancer Research 66
(15 April 2006); doi: 10.1158/0008-5472.CAN-05-4183Loss of Cell Polarity Drives Tumor Growth and Invasion through JNK Activation in Drosophila
Igaki, T, Pagliarini, R and Xu, T
Current Biology 16
(6 June 2006); doi: 10.1016/j.cub.2006.04.042Loss of Ikkbeta Promotes Migration and Proliferation of Mouse Embryo Fibroblast Cells
Chen, F. et al.
Journal of Biological Chemistry 281
(13 September 2006); doi: 10.1074/jbc.M603631200Complex networks orchestrate epithelial–mesenchymal transitions
Thiery, Jean Paul and Sleeman, Jonathan P.
Nature Reviews Molecular Cell Biology 7 131 - 142
doi: 10.1038/nrm1835Androgens modulate the inflammatory response during acute wound healing
Gilliver, S. C.
Journal of Cell Science 119
(15 February 2006); doi: 10.1242/jcs.02786Insulin-Like Growth Factor I Controls a Mutually Exclusive Association of RACK1 with Protein Phosphatase 2A and 1 Integrin To Promote Cell Migration
Kiely, P. A.
Molecular and Cellular Biology 26
(1 June 2006); doi: 10.1128/MCB.01868-05The G Protein GÎ
13 Is Required for Growth Factor-Induced Cell MigrationShan, D et al.
Developmental Cell 10
(10 February 0011); doi: 10.1016/j.devcel.2006.03.014Podoplanin binds ERM proteins to activate RhoA and promote epithelial-mesenchymal transition
Martin-villar, E. et al.
Journal of Cell Science 119
(1 November 2006); doi: 10.1242/jcs.03218Paxillin is essential for PTP-PEST-dependent regulation of cell spreading and motility: a role for paxillin kinase linker
Jamieson, J. S.
Journal of Cell Science 118
(15 December 2005); doi: 10.1242/jcs.02693Rac1 and Rac2 regulate macrophage morphology but are not essential for migration
Wheeler, A. P.
Journal of Cell Science 119
(6 June 2006); doi: 10.1242/jcs.03024Mast Cell-Associated TNF Promotes Dendritic Cell Migration
J Immunol
Analysis of Cell Migration Using Whole-Genome Expression Profiling of Migratory Cells in the Drosophila Ovary
Developmental Cell.
The P2Y12 receptor regulates microglial activation by extracellular nucleotides
Haynes, Sharon E et al.
Nature Neuroscience 9
(19 December 2006); doi: 10.1038/nn1805Systematic Analysis of the Transcriptional Switch Inducing Migration of Border Cells
Developmental Cell.
Reversal of Neuronal Migration in a Mouse Model of Fetal Alcohol Syndrome by Controlling Second-Messenger Signalings
Kumada, T.
Journal of Neuroscience 26
(18 January 2006); doi: 10.1523/JNEUROSCI.4478-05.2006Upregulation of chondroitin 6-sulphotransferase-1 facilitates Schwann cell migration during axonal growth
Liu, J.
Journal of Cell Science 119
(1 March 2006); doi: 10.1242/jcs.02796The c-Jun N-Terminal Kinase Activator Dual Leucine Zipper Kinase Regulates Axon Growth and Neuronal Migration in the Developing Cerebral Cortex
Hirai, S.-i. et al.
Journal of Neuroscience 26
(15 November 2006); doi: 10.1523/JNEUROSCI.2272-06.2006NO-dependent osteoclast motility: reliance on cGMP-dependent protein kinase I and VASP
Yaroslavskiy, B. B.
Journal of Cell Science 118
(1 December 2005); doi: 10.1242/jcs.02655The 2-adrenergic receptor activates pro-migratory and pro-proliferative pathways in dermal fibroblasts via divergent mechanisms
Pullar, C. E.
Journal of Cell Science 119
(1 February 2006); doi: 10.1242/jcs.02772Eph receptors inactivate R-Ras through different mechanisms to achieve cell repulsion
Dail, M.
Journal of Cell Science 119
(1 April 2006); doi: 10.1242/jcs.02842Epithelial cell motility is triggered by activation of the EGF receptor through phosphatidic acid signaling
Mazie, A. R.
Journal of Cell Science 119
(15 April 2006); doi: 10.1242/jcs.02858Plasma Membrane Organization Is Essential for Balancing Competing Pseudopod- and Uropod-promoting Signals during Neutrophil Polarization and Migration
Bodin, S.
Molecular Biology of the Cell 16
(21 September 2005); doi: 10.1091/mbc.E05-04-0358Migration of Zebrafish Primordial Germ Cells: A Role for Myosin Contraction and Cytoplasmic Flow
Blaser, H et al.
Developmental Cell 11
(11 December 0006); doi: 10.1016/j.devcel.2006.09.023The Ternary Complex Factor Net Regulates Cell Migration through Inhibition of PAI-1 Expression
Buchwalter, G.
Molecular and Cellular Biology 25
(15 December 2005); doi: 10.1128/MCB.25.24.10853-10862.2005Calcium-dependent interaction of Lis1 with IQGAP1 and Cdc42 promotes neuronal motility
Kholmanskikh, Stanislav S et al.
Nature Neuroscience 9 50 - 57
(20 December 2005); doi: 10.1038/nn1619Local force and geometry sensing regulate cell functions
Vogel, Viola and Sheetz, Michael
Nature Reviews Molecular Cell Biology 7 265 - 275
(22 February 2006); doi: 10.1038/nrm1890Rho Kinase Differentially Regulates Phosphorylation of Nonmuscle Myosin II Isoforms A and B during Cell Rounding and Migration
Sandquist, J. C. et al.
Journal of Biological Chemistry 281
(14 September 2006); doi: 10.1074/jbc.M605343200Distinct roles of Akt1 and Akt2 in regulating cell migration and epithelial-mesenchymal transition
Irie, H. Y.
The Journal of Cell Biology 171
(19 December 2005); doi: 10.1083/jcb.200505087Molecular Pathways Regulating Pro-migratory Effects of Hedgehog Signaling
Hochman, E. et al.
Journal of Biological Chemistry 281
(7 August 2006); doi: 10.1074/jbc.M605905200Activation of Rac1 by RhoG regulates cell migration
Katoh, H.
Journal of Cell Science 119
(1 January 2006); doi: 10.1242/jcs.02720The Oncogenic Epidermal Growth Factor Receptor Variant Xiphophorus Melanoma Receptor Kinase Induces Motility in Melanocytes by Modulation of Focal Adhesions
Meierjohann, S.
Cancer Research 66
(15 March 2006); doi: 10.1158/0008-5472.CAN-05-2667G 12/13 Is Essential for Directed Cell Migration and Localized Rho-Dia1 Function
Goulimari, P.
Journal of Biological Chemistry 280
(25 October 2005); doi: 10.1074/jbc.M508690200Rap1A-Deficient T and B Cells Show Impaired Integrin-Mediated Cell Adhesion
Duchniewicz, M.
Molecular and Cellular Biology 26
(15 January 2006); doi: 10.1128/MCB.26.2.643-653.2006RalB Mobilizes the Exocyst To Drive Cell Migration
Rosse, C.
Molecular and Cellular Biology 26
(15 January 2006); doi: 10.1128/MCB.26.2.727-734.2006