2010 Migration and Disease

• The RhoA Activator GEF-H1/Lfc Is a Transforming Growth Factor-  Target Gene and Effector That Regulates  -Smooth Muscle Actin Expression and Cell Migration

  Tsapara, A. et al.
  Molecular Biology of the Cell 21
  (15 March 2010); doi: 10.1091/mbc.E09-07-0567

  Abstract

• WNT11 Expression Is Induced by Estrogen-Related Receptor   and  -Catenin and Acts in an Autocrine Manner to Increase Cancer Cell Migration

  Dwyer, M. A. et al.
  Cancer Research 70
  (15 November 2010); doi: 10.1158/0008-5472.CAN-10-0226

  Abstract

• Bmi1 is essential in Twist1-induced epithelial–mesenchymal transition

  Yang, Muh-Hwa et al.
  Nature Cell Biology 12 982 - 992
  (5 September 2010); doi: 10.1038/ncb2099

  Abstract

• The impact of the extracellular matrix on inflammation

  Sorokin, Lydia
  Nature Reviews Immunology 10 712 - 723
  (24 September 2010); doi: 10.1038/nri2852

  Abstract

• Integrins in cancer: biological implications and therapeutic opportunities

  Desgrosellier, Jay S. and Cheresh, David A.
  Nature Reviews Cancer 10 9 - 22
  doi: 10.1038/nrc2748

  Abstract

• Cancer: Genomic evolution of metastasis

  Luebeck, E. Georg
  Nature 467 1053 - 1055
  (27 October 2010); doi: 10.1038/4671053a

  Abstract

• Planar Cell Polarity Acts Through Septins to Control Collective Cell Movement and Ciliogenesis

  Kim, S. K. et al.
  Science 329
  (10 September 2010); doi: 10.1126/science.1191184

  Abstract

• Pharmacological inhibition of EGFR signaling enhances G-CSF–induced hematopoietic stem cell mobilization

  Ryan, Marnie A et al.
  Nature Medicine 16 1141 - 1146
  (26 September 2010); doi: 10.1038/nm.2217

  Abstract

• Methyl-H3K9-binding protein MPP8 mediates E-cadherin gene silencing and promotes tumour cell motility and invasion

  Kokura, Kenji, Sun, Lidong, Bedford, Mark T and Fang, Jia
  The EMBO Journal 29 3673 - 3687
  (24 September 2010); doi: 10.1038/emboj.2010.239

  Abstract

• Activation of EGFR on monocytes is required for human cytomegalovirus entry and mediates cellular motility

  Chan, G., Nogalski, M. T. and Yurochko, A. D.
  Proceedings of the National Academy of Sciences 106
  (29 December 2009); doi: 10.1073/pnas.0908787106

  Abstract

• The tumor-associated EpCAM regulates morphogenetic movements through intracellular signaling

  Maghzal, N. et al.
  The Journal of Cell Biology 191
  (1 November 2010); doi: 10.1083/jcb.201004074

  Abstract

• Competition amongst Eph receptors regulates contact inhibition of locomotion and invasiveness in prostate cancer cells

  Astin, Jonathan W. et al.
  Nature Cell Biology 12 1194 - 1204
  (14 November 2010); doi: 10.1038/ncb2122

  Abstract

• JWA regulates melanoma metastasis by integrin α_Vβ₃ signaling

  Bai, J et al.
  Oncogene 29 1227 - 1237
  (30 November 2009); doi: 10.1038/onc.2009.408

  Abstract

• Actin-based motility drives baculovirus transit to the nucleus and cell surface

  Ohkawa, T., Volkman, L. E. and Welch, M. D.
  The Journal of Cell Biology 190
  (26 July 2010); doi: 10.1083/jcb.201001162

  Abstract

• Tissue remodelling through branching morphogenesis CMC

  Affolter, Markus, Zeller, Rolf and Caussinus, Emmanuel
  Nature Reviews Molecular Cell Biology 10 831 - 842
  doi: 10.1038/nrm2797

  Abstract

• TrkB induces EMT and has a key role in invasion of head and neck squamous cell carcinoma

  Kupferman, M E et al.
  Oncogene 29 2047 - 2059
  (18 January 2010); doi: 10.1038/onc.2009.486

  Abstract

• Podoplanin Associates with CD44 to Promote Directional Cell Migration

  Martin-villar, E. et al.
  Molecular Biology of the Cell
  (20 October 2010); doi: 10.1091/mbc.E10-06-0489

  Abstract

• Plasticity of cell migration: a multiscale tuning model

  Friedl, P. and Wolf, K.
  The Journal of Cell Biology 188
  (11 January 2010); doi: 10.1083/jcb.200909003

  Abstract

• Migration-associated secretion of melanoma inhibitory activity at the cell rear is supported by KCa3.1 potassium channels

  Schmidt, Jennifer et al.
  Cell Research 20
  (24 November 2010); doi: 10.1038/cr.2010.121

  Abstract

• Vascular endothelial platelet endothelial cell adhesion molecule 1 (PECAM-1) regulates advanced metastatic progression

  Delisser, H. et al.
  Proceedings of the National Academy of Sciences 107
  (26 October 2010); doi: 10.1073/pnas.1004654107

  Abstract

• Cancer Cells Cut Homophilic Cell Adhesion Molecules and Run

  Craig, S. E. L. and Brady-kalnay, S. M.
  Cancer Research
  (17 November 2010); doi: 10.1158/0008-5472.CAN-10-2301

  Abstract

• CAV1 Inhibits Metastatic Potential in Melanomas through Suppression of the Integrin/Src/FAK Signaling Pathway

  Trimmer, C. et al.
  Cancer Research 70
  (1 October 2010); doi: 10.1158/0008-5472.CAN-10-0900

  Abstract

• SHP2 Mediates the Localized Activation of Fyn Downstream of the  6 4 Integrin To Promote Carcinoma Invasion

  Yang, X., Dutta, U. and Shaw, L. M.
  Molecular and Cellular Biology 30
  (15 November 2010); doi: 10.1128/MCB.00326-10

  Abstract

• The Mitotic Kinase Aurora-A Induces Mammary Cell Migration and Breast Cancer Metastasis by Activating the Cofilin-F-actin Pathway

  Wang, L.-h. et al.
  Cancer Research 70
  (15 November 2010); doi: 10.1158/0008-5472.CAN-10-1246

  Abstract

• Implication of Metastasis Suppressor NM23-H1 in Maintaining Adherens Junctions and Limiting the Invasive Potential of Human Cancer Cells

  Boissan, M. et al.
  Cancer Research 70
  (1 October 2010); doi: 10.1158/0008-5472.CAN-10-1887

  Abstract

• Quantitative In vivo Imaging of the Effects of Inhibiting Integrin Signaling via Src and FAK on Cancer Cell Movement: Effects on E-cadherin Dynamics

  Canel, M. et al.
  Cancer Research 70
  (15 November 2010); doi: 10.1158/0008-5472.CAN-10-1454

  Abstract

• Hyaluronan-CD44 Interaction Promotes c-Src-mediated Twist Signaling, MicroRNA-10b Expression, and RhoA/RhoC Up-regulation, Leading to Rho-kinase-associated Cytoskeleton Activation and Breast Tumor Cell Invasion

  Bourguignon, L. Y. W. et al.
  Journal of Biological Chemistry 285
  (19 November 2010); doi: 10.1074/jbc.M110.162305

  Abstract

• miR-21 and miR-31 Converge on TIAM1 to Regulate Migration and Invasion of Colon Carcinoma Cells

  Cottonham, C. L., Kaneko, S. and Xu, L.
  Journal of Biological Chemistry 285
  (12 November 2010); doi: 10.1074/jbc.M110.160069

  Abstract