Subject archive
2005 Migration and Disease
Immune cell migration in inflammation: present and future therapeutic targets
Luster, Andrew D, Alon, Ronen and Von andrian, Ulrich H
Nature Immunology 6 1182 - 1190
(17 November 2005); doi: 10.1038/ni1275Monocyte Adhesion to Xenogeneic Endothelium during Laminar Flow Is Dependent on a-Gal-Mediated Monocyte Activation
The Journal of Immunology
Quantum Proteolytic Activation of Chemokine CCL15 by Neutrophil Granulocytes Modulates Mononuclear Cell Adhesiveness
The Journal of Immunology
15(S)-Hydroxyeicosatetraenoic Acid Induces Angiogenesis via Activation of PI3K-Akt-mTOR-S6K1 Signaling
Cancer Research
Breast cancer metastasis: markers and models
Weigelt, Britta, Peterse, Johannes L. and Van't veer, Laura J.
Nature Reviews Cancer 5 591 - 602
doi: 10.1038/nrc1670The CD44 Receptor Interacts with P-Glycoprotein to Promote Cell Migration and Invasion in Cancer
Cancer Research
Hypersialylation of B1 Integrins, Observed in Colon Adenocarcinoma, May Contribute to Cancer Progression by Up-regulating Cell Motility
Cancer Research
CD44 Attenuates Metastatic Invasion during Breast Cancer Progression
Cancer Research
Inhibition of Adhesion, Invasion, and Metastasis by Antibodies Targeting CEACAM6 (NCA-90) and CEACAM5 (Carcinoembryonic Antigen)
Cancer Res.
FAK signaling is critical for ErbB-2/ErbB-3 receptor cooperation for oncogenic transformation and invasion
Benlimame, N.
The Journal of Cell Biology 171
(31 October 2005); doi: 10.1083/jcb.200504124Requirement for Focal Adhesion Kinase in the Early Phase of Mammary Adenocarcinoma Lung Metastasis Formation
Cancer Research
RalA and RalB: Antagonistic Relatives in Cancer Cell Migration
Cancer Research
Bordetella Type III Secretion Modulates Dendritic Cell Migration Resulting in Immunosuppression and Bacterial Persistence
J Immunol.
A Secreted Form of ADAM9 Promotes Carcinoma Invasion through Tumor-Stromal Interactions
Cancer Research
c-Src-Mediated Phosphorylation of TRIP6 Regulates Its Function in Lysophosphatidic Acid-Induced Cell Migration
Mol. Cell. Biol.
Endogenous Osteonectin/SPARC/BM-40 Expression Inhibits MDA-MB-231 Breast Cancer Cell Metastasis
Cancer Research
Induction of Keratinocyte Migration via Transactivation of the Epidermal Growth Factor Receptor by the Antimicrobial Peptide LL-37
J Immunol.
Going against the grain: chemotaxis and infection in Vibrio cholerae
Butler, Susan M. and Camilli, Andrew
Nature Reviews Microbiology 3 611 - 620
(11 July 2005); doi: 10.1038/nrmicro1207Vascular Endothelial Cell Growth Factor Receptor 3-Mediated Activation of Lymphatic Endothelium Is Crucial for Tumor Cell Entry and Spread via Lymphatic Vessels
Cancer Research
Bcl-2 Promotes Invasion and Lung Metastasis by Inducing Matrix Metalloproteinase-2
Cancer Res.
Claudin-3 and Claudin-4 Expression in Ovarian Epithelial Cells Enhances Invasion and Is Associated with Increased Matrix Metalloproteinase-2 Activity
Cancer Research
Inhibition of Rho-Kinase Affects Astrocytoma Morphology, Motility, and Invasion through Activation of Rac1
Cancer Res.
Lack of Telopeptides in Fibrillar Collagen I Promotes the Invasion of a Metastatic Breast Tumor Cell Line
Cancer Res.
The Journal of Immunology
Inhibition of Adhesion, Invasion, and Metastasis by Antibodies Targeting CEACAM6 (NCA-90) and CEACAM5 (Carcinoembryonic Antigen)
Cancer Res.
Activation of the Canonical Wnt Pathway during Genital Keratinocyte Transformation: A Model for Cervical Cancer Progression
Cancer Res.
The Journal of Immunology
Inhibition of Rho-Kinase Affects Astrocytoma Morphology, Motility, and Invasion through Activation of Rac1
Cancer Res.
Taking the lid off focal adhesions
J. Cell Sci.
Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo
Chen, Juhua et al.
Nature Medicine 11 1188 - 1196
(16 October 2005); doi: 10.1038/nm1307Heat Shock Protein 60 Activates Cytokine-Associated Negative Regulator Suppressor of Cytokine Signaling 3 in T Cells: Effects on Signaling, Chemotaxis, and Inflammation
J Immunol.
Insulin-Like Growth Factor Binding Protein-5 Is a Target of Matrix Metalloproteinase-7: Implications for Epithelial-Mesenchymal Signaling
Cancer Research
Impact of Cutaneous IL-10 on Resident Epidermal Langerhans' Cells and the Development of Polarized Immune Responses
J Immunol.
A Network of PDZ-Containing Proteins Regulates T Cell Polarity and Morphology during Migration and Immunological Synapse Formation
Immunity
Rules of Recruitment for Th1 and Th2 Lymphocytes in Inflamed Liver: A Role for Alpha-4 Integrin and Vascular Adhesion Protein-1
Immunity
The melanocyte differentiation program predisposes to metastasis after neoplastic transformation
Gupta, Piyush B et al.
Nature Genetics 37 1047 - 1054
(4 September 2005); doi: 10.1038/ng1634The Journal of Immunology
Neutrophils Lacking Platelet-Endothelial Cell Adhesion Molecule-1 Exhibit Loss of Directionality and Motility in CXCR2-Mediated Chemotaxis
The Journal of Immunology
A Specific Microdomain ("Glycosynapse 3") Controls Phenotypic Conversion and Reversion of Bladder Cancer Cells through GM3-mediated Interaction of 3 1 Integrin with CD9
Mitsuzuka, K.
Journal of Biological Chemistry 280
(24 August 2005); doi: 10.1074/jbc.M505630200A Non-Glycosaminoglycan-Binding Variant of CC Chemokine Ligand 7 (Monocyte Chemoattractant Protein-3) Antagonizes Chemokine-Mediated Inflammation
The Journal of Immunology
Syk Is Required for Monocyte/Macrophage Chemotaxis to CX3CL1 (Fractalkine)
The Journal of Immunology
The Androgen Derivative 5a -Androstane-3
,17-Diol Inhibits Prostate Cancer Cell Migration Through Activation of the Estrogen Receptor SubtypeCancer Res.
Quantum Proteolytic Activation of Chemokine CCL15 by Neutrophil Granulocytes Modulates Mononuclear Cell Adhesiveness
The Journal of Immunology
Involvement of the RASSF1A Tumor Suppressor Gene in Controlling Cell Migration
Cancer Research
Heat Shock Protein 70 Surface-Positive Tumor Exosomes Stimulate Migratory and Cytolytic Activity of Natural Killer Cells
Cancer Res.
Characteristics of NK Cell Migration Early after Vaccinia Infection
The Journal of Immunology
Rules of Recruitment for Th1 and Th2 Lymphocytes in Inflamed Liver: A Role for Alpha-4 Integrin and Vascular Adhesion Protein-1
Immunity
Macrophages Promote the Invasion of Breast Carcinoma Cells via a Colony-Stimulating Factor-1/Epidermal Growth Factor Paracrine Loop
Cancer Res.
CC Chemokine Ligand 19 Secreted by Mature Dendritic Cells Increases Naive T Cell Scanning Behavior and Their Response to Rare Cognate Antigen
The Journal of Immunology
Sphingosine 1-Phosphate Receptors Regulate Chemokine-Driven Transendothelial Migration of Lymph Node but Not Splenic T Cells
The Journal of Immunology
Wounding activates p38 map kinase and activation transcription factor 3 in leading keratinocytes
Harper, E. G.
Journal of Cell Science 118
(1 August 2005); doi: 10.1242/jcs.02475Cutting Edge: Egress of Newly Generated Plasma Cells from Peripheral Lymph Nodes Depends on B2 Integrin
The Journal of Immunology
Carcinoma Invasion and Metastasis: A Role for Epithelial-Mesenchymal Transition?
Cancer Res.
Cutting Edge: Chemoattractant Receptor-Homologous Molecule Expressed on TH2 Cells Plays a Restricting Role on IL-5 Production and Eosinophil Recruitment
The Journal of Immunology
Sphingosine-1-Phosphate Mediates Migration of Mature Dendritic Cells
The Journal of Immunology
The Fallacy of Epithelial Mesenchymal Transition in Neoplasia
Cancer Res.
Neutrophils Lacking Platelet-Endothelial Cell Adhesion Molecule-1 Exhibit Loss of Directionality and Motility in CXCR2-Mediated Chemotaxis
The Journal of Immunology
Improved muscle healing through enhanced regeneration and reduced fibrosis in myostatin-null mice
Mccroskery, S.
Journal of Cell Science 118
(1 August 2005); doi: 10.1242/jcs.02482A Five-Amino-Acid Peptide Blocks Met- and Ron-Dependent Cell Migration
Cancer Res.
Syk Is Required for Monocyte/Macrophage Chemotaxis to CX3CL1 (Fractalkine)
The Journal of Immunology
A Mouse Model of Human Breast Cancer Metastasis to Human Bone
Proteolytic Processing Converts the Repelling Signal Sema3E into an Inducer of Invasive Growth and Lung Metastasis
Cancer Res.
Proteolytic maturation and activation of autotaxin (NPP2), a secreted metastasis-enhancing lysophospholipase D
Jansen, S.
Journal of Cell Science 118
(15 July 2005); doi: 10.1242/jcs.02438Migrating cancer stem cells — an integrated concept of malignant tumour progression
Brabletz, Thomas et al.
Nature Reviews Cancer 5 744 - 749
doi: 10.1038/nrc1694Chemokines: Integrators of Pain and Inflammation
White, Fletcher A., Bhangoo, Sonia K. and Miller, Richard J.
Nature Reviews Drug Discovery 4 834 - 844
doi: 10.1038/nrd1852Impact of Cutaneous IL-10 on Resident Epidermal Langerhans' Cells and the Development of Polarized Immune Responses
J Immunol.
Role for macrophage migration inhibitory factor in asthma
Mizue, Y.
Proceedings of the National Academy of Sciences 102
(27 September 2005); doi: 10.1073/pnas.0507189102Cell junction-associated proteins IQGAP1, MAGI-2, CASK, spectrins, and -actinin are components of the nephrin multiprotein complex
Lehtonen, S.
Proceedings of the National Academy of Sciences 102
(12 July 2005); doi: 10.1073/pnas.0504166102Tumor Cell Pseudopodial Protrusions: LOCALIZED SIGNALING DOMAINS COORDINATING CYTOSKELETON REMODELING, CELL ADHESION, GLYCOLYSIS, RNA TRANSLOCATION, AND PROTEIN TRANSLATION
Jia, Z.
Journal of Biological Chemistry 280
(13 July 2005); doi: 10.1074/jbc.M501754200Integrin Regulation by RhoA in Thymocytes
J Immunol.
Accelerated chemokine receptor 7-mediated dendritic cell migration in Runx3 knockout mice and the spontaneous development of asthma-like disease
Fainaru, O.
Proceedings of the National Academy of Sciences 102
(26 July 2005); doi: 10.1073/pnas.0504787102LIS1 RNA interference blocks neural stem cell division, morphogenesis, and motility at multiple stages
Tsai, J.-W.
The Journal of Cell Biology 170
(12 September 2005); doi: 10.1083/jcb.200505166The CD44 Receptor Interacts with P-Glycoprotein to Promote Cell Migration and Invasion in Cancer
Cancer Research
Blockade of PI3K
suppresses joint inflammation and damage in mouse models of rheumatoid arthritisCamps, Montserrat et al.
Nature Medicine 11 936 - 943
(28 August 2005); doi: 10.1038/nm1284CD44 Attenuates Metastatic Invasion during Breast Cancer Progression
Cancer Researc
A genetic Xenopus laevis tadpole model to study lymphangiogenesis
Ny, Annelii et al.
Nature Medicine 11 998 - 1004
(14 August 2005); doi: 10.1038/nm1285RalA and RalB: Antagonistic Relatives in Cancer Cell Migration
Cancer Research
15(S)-Hydroxyeicosatetraenoic Acid Induces Angiogenesis via Activation of PI3K-Akt-mTOR-S6K1 Signaling
Cancer Research
Insulin-Like Growth Factor Binding Protein-5 Is a Target of Matrix Metalloproteinase-7: Implications for Epithelial-Mesenchymal Signaling
Cancer Research
Endogenous Osteonectin/SPARC/BM-40 Expression Inhibits MDA-MB-231 Breast Cancer Cell Metastasis
Cancer Research
Claudin-3 and Claudin-4 Expression in Ovarian Epithelial Cells Enhances Invasion and Is Associated with Increased Matrix Metalloproteinase-2 Activity
Cancer Research
A Network of PDZ-Containing Proteins Regulates T Cell Polarity and Morphology during Migration and Immunological Synapse Formation
Immunity
The Journal of Immunology
The Journal of Immunology
The Journal of Immunology
Quantum Proteolytic Activation of Chemokine CCL15 by Neutrophil Granulocytes Modulates Mononuclear Cell Adhesiveness
The Journal of Immunology
The Journal of Immunology
CC Chemokine Ligand 19 Secreted by Mature Dendritic Cells Increases Naive T Cell Scanning Behavior and Their Response to Rare Cognate Antigen
The Journal of Immunology
Cutting Edge: Chemoattractant Receptor-Homologous Molecule Expressed on TH2 Cells Plays a Restricting Role on IL-5 Production and Eosinophil Recruitment
The Journal of Immunology