2011 Extracellular Matrix

• Biomechanical Remodeling of the Microenvironment by Stromal Caveolin-1 Favors Tumor Invasion and Metastasis

  Goetz, Jacky G. et al.
  Cell 146
  (1 July 2011); doi: 10.1016/j.cell.2011.05.040

  Abstract

• Global Tissue Revolutions in a Morphogenetic Movement Controlling Elongation

  Haigo, S. L. and Bilder, D.
  Science 331
  (25 February 2011); doi: 10.1126/science.1199424

  Abstract

• A Hitchhiker's Guide to Mechanobiology

  Eyckmans, Jeroen, Boudou, Thomas, Yu, Xiang and Chen, Christopher S.
  Developmental Cell 21
  (1 July 2011); doi: 10.1016/j.devcel.2011.06.015

  Abstract

• Analyzing the Anatomy of Integrin Adhesions

  Byron, A.
  Science Signaling 4
  (26 April 2011); doi: 10.1126/scisignal.2001896

  Abstract

• CCL18 from Tumor-Associated Macrophages Promotes Breast Cancer Metastasis via PITPNM3

  Chen, Jingqi et al.
  Cancer Cell 19
  (1 April 2011); doi: 10.1016/j.ccr.2011.02.006

  Abstract

• In vivo functional analysis reveals specific roles for the integrin-binding sites of talin

  Ellis, S. J., Pines, M., Fairchild, M. J. and Tanentzapf, G.
  Journal of Cell Science 124
  (1 June 2011); doi: 10.1242/jcs.083337

  Abstract

• Kindlin-2 regulates podocyte adhesion and fibronectin matrix deposition through interactions with phosphoinositides and integrins

  Qu, H. et al.
  Journal of Cell Science 124
  (15 March 2011); doi: 10.1242/jcs.076976

  Abstract

• Interdependency of cell adhesion, force generation and extracellular proteolysis in matrix remodeling

  Kirmse, R., Otto, H. and Ludwig, T.
  Journal of Cell Science 124
  (1 June 2011); doi: 10.1242/jcs.079343

  Abstract

• Distinct ECM mechanosensing pathways regulate microtubule dynamics to control endothelial cell branching morphogenesis CMC

  Myers, K. A. et al.
  The Journal of Cell Biology 192
  (24 January 2011); doi: 10.1083/jcb.201006009

  Abstract

• Adhesion signalling complexes

  Byron, Adam, Morgan, Mark R. and Humphries, Martin J.
  Current Biology 20
  (1 December 2010); doi: 10.1016/j.cub.2010.10.059

  Abstract

• Cdc42-interacting protein 4 is a Src substrate that regulates invadopodia and invasiveness of breast tumors by promoting MT1-MMP endocytosis

  Hu, J. et al.
  Journal of Cell Science 124
  (15 May 2011); doi: 10.1242/jcs.078014

  Abstract

• The guanine nucleotide exchange factor Arhgef5 plays crucial roles in Src-induced podosome formation

  Kuroiwa, M., Oneyama, C., Nada, S. and Okada, M.
  Journal of Cell Science 124
  (15 May 2011); doi: 10.1242/jcs.080291

  Abstract

• Identification of integrin   subunit mutations that alter affinity for extracellular matrix ligand

  Kendall, T., Mukai, L., Jannuzi, A. L. and Bunch, T. A.
  Journal of Biological Chemistry
  (11 July 2011); doi: 10.1074/jbc.M111.254797

  Abstract

• Type XVII Collagen Regulates Lamellipod Stability, Cell Motility, and Signaling to Rac1 by Targeting Bullous Pemphigoid Antigen 1e to  6 4 Integrin

  Hamill, K. J., Hopkinson, S. B., Jonkman, M. F. and Jones, J. C. R.
  Journal of Biological Chemistry 286
  (29 July 2011); doi: 10.1074/jbc.M110.203646

  Abstract

• Zeppo1 is a novel metastasis promoter that represses E-cadherin expression and regulates p120-catenin isoform expression and localization

  Slorach, E. M., Chou, J. and Werb, Z.
  Genes & Development 25
  (1 March 2011); doi: 10.1101/gad.1998111

  Abstract

• Integrin  5 1 facilitates cancer cell invasion through enhanced contractile forces

  Mierke, C. T. et al.
  Journal of Cell Science 124
  (1 February 2011); doi: 10.1242/jcs.071985

  Abstract

• Actomyosin-generated tension controls the molecular kinetics of focal adhesions CMC

  Wolfenson, H., Bershadsky, A., Henis, Y. I. and Geiger, B.
  Journal of Cell Science 124
  (1 May 2011); doi: 10.1242/jcs.077388

  Abstract

• Quantitative proteomics of the integrin adhesome show a myosin II-dependent recruitment of LIM domain proteins

  Schiller, Herbert B, Friedel, Caroline C, Boulegue, Cyril and Fässler, Reinhard
  EMBO reports 12 259 - 266
  (11 February 2011); doi: 10.1038/embor.2011.5

  Abstract

• Integrins and cadherins join forces to form adhesive networks

  Weber, G. F., Bjerke, M. A. and Desimone, D. W.
  Journal of Cell Science 124
  (15 April 2011); doi: 10.1242/jcs.064618

  Abstract

• Mesenchymal stem cell migration is regulated by fibronectin through  5 1-integrin-mediated activation of PDGFR-  and potentiation of growth factor signals

  Veevers-lowe, J., Ball, S. G., Shuttleworth, A. and Kielty, C. M.
  Journal of Cell Science 124
  (15 April 2011); doi: 10.1242/jcs.076935

  Abstract

• Pancreatic Cancer Cells Respond to Type I Collagen by Inducing Snail Expression to Promote Membrane Type 1 Matrix Metalloproteinase-dependent Collagen Invasion

  Shields, M. A. et al.
  Journal of Biological Chemistry 286
  (25 March 2011); doi: 10.1074/jbc.M110.195628

  Abstract

• The extracellular matrix at a glance

  Frantz, C., Stewart, K. M. and Weaver, V. M.
  Journal of Cell Science 123
  (15 December 2010); doi: 10.1242/jcs.023820

  Abstract

• Mechanisms of mechanical signaling in development and disease

  Janmey, P. A. and Miller, R. T.
  Journal of Cell Science 124
  (1 January 2011); doi: 10.1242/jcs.071001

  Abstract

• Rap1-GTP-interacting Adaptor Molecule (RIAM) Protein Controls Invasion and Growth of Melanoma Cells

  Hernandez-varas, P. et al.
  Journal of Biological Chemistry 286
  (27 May 2011); doi: 10.1074/jbc.M110.189811

  Abstract

• Dermatopontin Interacts with Fibronectin, Promotes Fibronectin Fibril Formation, and Enhances Cell Adhesion

  Kato, A. et al.
  Journal of Biological Chemistry 286
  (29 April 2011); doi: 10.1074/jbc.M110.179762

  Abstract

• Cell-ECM traction force modulates endogenous tension at cell-cell contacts

  Maruthamuthu, V., Sabass, B., Schwarz, U. S. and Gardel, M. L.
  Proceedings of the National Academy of Sciences 108
  (22 March 2011); doi: 10.1073/pnas.1011123108

  Abstract

• Identification of Novel and Distinct Binding Sites within Tenascin-C for Soluble and Fibrillar Fibronectin

  To, W. S. and Midwood, K. S.
  Journal of Biological Chemistry 286
  (29 April 2011); doi: 10.1074/jbc.M110.189019

  Abstract

• Dynamic and structural signatures of lamellar actomyosin force generation

  Aratyn-schaus, Y., Oakes, P. W. and Gardel, M. L.
  Molecular Biology of the Cell 22
  (15 April 2011); doi: 10.1091/mbc.E10-11-0891

  Abstract

•  1A Integrin Is a Master Regulator of Invadosome Organization and Function

  Destaing, O. et al.
  Molecular Biology of the Cell 21
  (1 December 2010); doi: 10.1091/mbc.E10-07-0580

  Abstract

• c-Src-Mediated Phosphorylation of NoxA1 and Tks4 Induces the Reactive Oxygen Species (ROS)-Dependent Formation of Functional Invadopodia in Human Colon Cancer Cells

  Gianni, D., Taulet, N., Dermardirossian, C. and Bokoch, G. M.
  Molecular Biology of the Cell 21
  (1 December 2010); doi: 10.1091/mbc.E10-08-0685

  Abstract

• Distinct roles for paxillin and Hic-5 in regulating breast cancer cell morphology, invasion, and metastasis

  Deakin, N. O. and Turner, C. E.
  Molecular Biology of the Cell 22
  (1 February 2011); doi: 10.1091/mbc.E10-09-0790

  Abstract

• Structure-Function Analysis of Tetraspanin CD151 Reveals Distinct Requirements for Tumor Cell Behaviors Mediated by  3 1 versus  6 4 Integrin

  Zevian, S., Winterwood, N. E. and Stipp, C. S.
  Journal of Biological Chemistry 286
  (4 March 2011); doi: 10.1074/jbc.M110.173583

  Abstract

• Multizone Paper Platform for 3D Cell Cultures

  Derda, Ratmir et al.
  PLoS ONE 6
  (6 May 2011); doi: 10.1371/journal.pone.0018940

  Abstract

• Keratinocyte-derived Laminin-332 Promotes Adhesion and Migration in Melanocytes and Melanoma

  Chung, H., Suh, E.-K., Han, I.-O. and Oh, E.-S.
  Journal of Biological Chemistry 286
  (15 April 2011); doi: 10.1074/jbc.M110.166751

  Abstract

• Vascular Endothelial Growth Factor A (VEGF-A) Induces Endothelial and Cancer Cell Migration through Direct Binding to Integrin  9 1: IDENTIFICATION OF A SPECIFIC  9 1 BINDING SITE

  Oommen, S., Gupta, S. K. and Vlahakis, N. E.
  Journal of Biological Chemistry 286
  (14 January 2011); doi: 10.1074/jbc.M110.175158

  Abstract

• Elucidating the Role of Matrix Stiffness in 3D Cell Migration and Remodeling

  Ehrbar, M. et al.
  Biophysical Journal 100
  (19 January 2011); doi: 10.1016/j.bpj.2010.11.082

  Abstract

• Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs

  Oskarsson, Thordur et al.
  Nature Medicine 17 867 - 874
  (26 June 2011); doi: 10.1038/nm.2379

  Abstract

• Three-Dimensional Traction Force Microscopy: A New Tool for Quantifying Cell-Matrix Interactions

  Franck, Christian et al.
  PLoS ONE 6
  (29 March 2011); doi: 10.1371/journal.pone.0017833

  Abstract

• Integrin Activation Promotes Axon Growth on Inhibitory Chondroitin Sulfate Proteoglycans by Enhancing Integrin Signaling

  Tan, C. L. et al.
  Journal of Neuroscience 31
  (27 April 2011); doi: 10.1523/JNEUROSCI.0008-11.2011

  Abstract

• Tumor Cell Invasion Is Promoted by Interstitial Flow-Induced Matrix Priming by Stromal Fibroblasts

  Shieh, A. C., Rozansky, H. A., Hinz, B. and Swartz, M. A.
  Cancer Research 71
  (1 February 2011); doi: 10.1158/0008-5472.CAN-10-1513

  Abstract

• Role of YAP/TAZ in mechanotransduction

  Dupont, Sirio et al.
  Nature 474 179 - 183
  (8 June 2011); doi: 10.1038/nature10137

  Abstract

• Cancer Cell Migration: Integrated Roles of Matrix Mechanics and Transforming Potential

  Baker, Erin L. et al.
  PLoS ONE 6
  (27 May 2011); doi: 10.1371/journal.pone.0020355

  Abstract

• Signaling Network Triggers and Membrane Physical Properties Control the Actin Cytoskeleton-Driven Isotropic Phase of Cell Spreading

  Rangamani, Padmini et al.
  Biophysical Journal 100
  (16 February 2011); doi: 10.1016/j.bpj.2010.12.3732

  Abstract

• The 'ins' and 'outs' of podosomes and invadopodia: characteristics, formation and function

  Murphy, Danielle A. and Courtneidge, Sara A.
  Nature Reviews Molecular Cell Biology 12 413 - 426
  (23 June 2011); doi: 10.1038/nrm3141

  Abstract

• Cancer Cell Invasion Is Enhanced by Applied Mechanical Stimulation

  Menon, Shalini, Beningo, Karen A. and Gullberg, Donald
  PLoS ONE 6
  (17 February 2011); doi: 10.1371/journal.pone.0017277

  Abstract

• Interactions Between Laminin Receptor and the Cytoskeleton During Translation and Cell Motility

  Venticinque, Lisa, Jamieson, Kelly V., Meruelo, Daniel and Parsons, Maddy
  PLoS ONE 6
  (7 January 2011); doi: 10.1371/journal.pone.0015895

  Abstract

• The physics of cancer: the role of physical interactions and mechanical forces in metastasis

  Wirtz, Denis, Konstantopoulos, Konstantinos and Searson, Peter C.
  Nature Reviews Cancer 11 512 - 522
  (24 June 2011); doi: 10.1038/nrc3080

  Abstract

• Differential Expressions of Adhesive Molecules and Proteases Define Mechanisms of Ovarian Tumor Cell Matrix Penetration/Invasion

  Kwon, Youngjoo, Cukierman, Edna, Godwin, Andrew K. and Orsulic, Sandra
  PLoS ONE 6
  (19 April 2011); doi: 10.1371/journal.pone.0018872

  Abstract