2010 Immunology

• The impact of the extracellular matrix on inflammation

  Sorokin, Lydia
  Nature Reviews Immunology 10 712 - 723
  (24 September 2010); doi: 10.1038/nri2852

  Abstract

• Confinement-optimized three-dimensional T cell amoeboid motility is modulated via myosin IIA–regulated adhesions

  Jacobelli, Jordan et al.
  Nature Immunology 11 953 - 961
  (12 September 2010); doi: 10.1038/ni.1936

  Abstract

• The polarization of immune cells in the tumour environment by TGFβ

  Flavell, Richard A., Sanjabi, Shomyseh, Wrzesinski, Stephen H. and Licona-limón, Paula
  Nature Reviews Immunology 10 554 - 567
  (9 July 2010); doi: 10.1038/nri2808

  Abstract

• Neutrophil Transmigration Mediated by the Neutrophil-Specific Antigen CD177 Is Influenced by the Endothelial S536N Dimorphism of Platelet Endothelial Cell Adhesion Molecule-1

  Bayat, B. et al.
  The Journal of Immunology 184
  (1 April 2010); doi: 10.4049/jimmunol.0903136

  Abstract

• A Proinflammatory Role for Proteolytically Cleaved Annexin A1 in Neutrophil Transendothelial Migration

  Williams, S. L. et al.
  The Journal of Immunology 185
  (1 September 2010); doi: 10.4049/jimmunol.1000119

  Abstract

• Pharmacological inhibition of EGFR signaling enhances G-CSF–induced hematopoietic stem cell mobilization

  Ryan, Marnie A et al.
  Nature Medicine 16 1141 - 1146
  (26 September 2010); doi: 10.1038/nm.2217

  Abstract

• The Migration of T Cells in Response to Influenza Virus Is Altered in Neonatal Mice

  Lines, J. L. et al.
  The Journal of Immunology 185
  (1 September 2010); doi: 10.4049/jimmunol.0903075

  Abstract

• Intravascular Danger Signals Guide Neutrophils to Sites of Sterile Inflammation

  Mcdonald, B. et al.
  Science 330
  (15 October 2010); doi: 10.1126/science.1195491

  Abstract

• Cancer Dissemination—Lessons from Leukocytes

  Madsen, Chris D. and Sahai, Erik
  Developmental Cell 19
  (20 July 2010); doi: 10.1016/j.devcel.2010.06.013

  Abstract

• Regulation of thymocyte positive selection and motility by GIT2

  Phee, Hyewon et al.
  Nature Immunology 11 503 - 511
  (2 May 2010); doi: 10.1038/ni.1868

  Abstract

• Tumor-Conditioned Macrophages Secrete Migration-Stimulating Factor: A New Marker for M2-Polarization, Influencing Tumor Cell Motility

  Solinas, G. et al.
  The Journal of Immunology 185
  (1 July 2010); doi: 10.4049/jimmunol.1000413

  Abstract

• Dendritic cell podosomes are protrusive and invade the extracellular matrix using metalloproteinase MMP-14

  Gawden-bone, C. et al.
  Journal of Cell Science 123
  (1 May 2010); doi: 10.1242/jcs.056515

  Abstract

• Synaptotagmin-mediated vesicle fusion regulates cell migration

  Colvin, Richard A et al.
  Nature Immunology 11 495 - 502
  (16 May 2010); doi: 10.1038/ni.1878

  Abstract

• Mast cells regulate homeostatic intestinal epithelial migration and barrier function by a chymase/Mcpt4-dependent mechanism

  Groschwitz, K. R. et al.
  Proceedings of the National Academy of Sciences 106
  (29 December 2009); doi: 10.1073/pnas.0906372106

  Abstract

• Integrin-Induced PIP5K1C Kinase Polarization Regulates Neutrophil Polarization, Directionality, and In Vivo Infiltration

  Xu, Wenwen et al.
  Immunity 33
  (24 September 2010); doi: 10.1016/j.immuni.2010.08.015

  Abstract

• Intravital Imaging Reveals Distinct Dynamics for Natural Killer and CD8+ T Cells during Tumor Regression

  Deguine, Jacques et al.
  Immunity 33
  (29 October 2010); doi: 10.1016/j.immuni.2010.09.016

  Abstract

• Coordinated RhoA signaling at the leading edge and uropod is required for T cell transendothelial migration

  Heasman, S. J. et al.
  The Journal of Cell Biology 190
  (23 August 2010); doi: 10.1083/jcb.201002067

  Abstract

• Lumican is required for neutrophil extravasation following corneal injury and wound healing

  Hayashi, Y. et al.
  Journal of Cell Science 123
  (1 September 2010); doi: 10.1242/jcs.068221

  Abstract

• Optimal Germinal Center Responses Require a Multistage T Cell:B Cell Adhesion Process Involving Integrins, SLAM-Associated Protein, and CD84

  Cannons, Jennifer L. et al.
  Immunity 32
  (26 February 2010); doi: 10.1016/j.immuni.2010.01.010

  Abstract

• Tumor-mediated liver X receptor-α activation inhibits CC chemokine receptor-7 expression on dendritic cells and dampens antitumor responses

  Villablanca, Eduardo J et al.
  Nature Medicine 16 98 - 105
  (27 December 2009); doi: 10.1038/nm.2074

  Abstract

• The Actin-Bundling Protein L-Plastin Dissociates CCR7 Proximal Signaling from CCR7-Induced Motility

  Morley, S. C. et al.
  The Journal of Immunology 184
  (1 April 2010); doi: 10.4049/jimmunol.0903851

  Abstract

• Phosphorylation of Leukocyte PECAM and Its Association with Detergent-Resistant Membranes Regulate Transendothelial Migration

  Florey, O., Durgan, J. and Muller, W.
  The Journal of Immunology 185
  (1 August 2010); doi: 10.4049/jimmunol.1001305

  Abstract

• An MEK-cofilin signalling module controls migration of human T cells in 3D but not 2D environments

  Klemke, Martin et al.
  The EMBO Journal 29 2915 - 2929
  (30 July 2010); doi: 10.1038/emboj.2010.153

  Abstract

• Extracellular Matrix of Glioblastoma Inhibits Polarization and Transmigration of T Cells: The Role of Tenascin-C in Immune Suppression

  Huang, J.-Y. et al.
  The Journal of Immunology 185
  (1 August 2010); doi: 10.4049/jimmunol.0901352

  Abstract

• Mechanisms of force generation and force transmission during interstitial leukocyte migration

  Renkawitz, Jörg and Sixt, Michael
  EMBO reports 11 744 - 750
  (24 September 2010); doi: 10.1038/embor.2010.147

  Abstract

• T Cell Receptor “Inside-Out” Pathway via Signaling Module SKAP1-RapL Regulates T Cell Motility and Interactions in Lymph Nodes

  Raab, Monika et al.
  Immunity 32
  (23 April 2010); doi: 10.1016/j.immuni.2010.03.007

  Abstract

• Immune infiltration in human tumors: a prognostic factor that should not be ignored

  Pagès, F et al.
  Oncogene 29 1093 - 1102
  (30 November 2009); doi: 10.1038/onc.2009.416

  Abstract

• An Alternative Role of C1q in Cell Migration and Tissue Remodeling: Contribution to Trophoblast Invasion and Placental Development

  Agostinis, C. et al.
  The Journal of Immunology 185
  (1 October 2010); doi: 10.4049/jimmunol.0903215

  Abstract

• WASP: a key immunological multitasker

  Thrasher, Adrian J. and Burns, Siobhan O.
  Nature Reviews Immunology 10 182 - 192
  doi: 10.1038/nri2724

  Abstract

• A Novel Pseudopodial Component of the Dendritic Cell Anti-Fungal Response: The Fungipod CMC

  Neumann, Aaron K., Jacobson, Ken and May, Robin Charles
  PLoS Pathogens 6
  (12 February 2010); doi: 10.1371/journal.ppat.1000760

  Abstract

• Acute Hypoxia Induces HIF-Independent Monocyte Adhesion to Endothelial Cells through Increased Intercellular Adhesion Molecule-1 Expression: The Role of Hypoxic Inhibition of Prolyl Hydroxylase Activity for the Induction of NF- B

  Winning, S., Splettstoesser, F., Fandrey, J. and Frede, S.
  The Journal of Immunology 185
  (1 August 2010); doi: 10.4049/jimmunol.0903244

  Abstract

• Junctional Adhesion Molecule-C Is a Soluble Mediator of Angiogenesis

  Rabquer, B. J. et al.
  The Journal of Immunology 185
  (1 August 2010); doi: 10.4049/jimmunol.1000556

  Abstract