Subject archive
2005 Caenorhabditis elegans
Genes that mediate breast cancer metastasis to lung
Minn, Andy J. et al.
Nature 436 518 - 524
doi: 10.1038/nature03799The role of focal-adhesion kinase in cancer — a new therapeutic opportunity
Mclean, Gordon W. et al.
Nature Reviews Cancer 5 505 - 515
doi: 10.1038/nrc1647Monocyte Adhesion to Xenogeneic Endothelium during Laminar Flow Is Dependent on a-Gal-Mediated Monocyte Activation
The Journal of Immunology
Quantum Proteolytic Activation of Chemokine CCL15 by Neutrophil Granulocytes Modulates Mononuclear Cell Adhesiveness
The Journal of Immunology
Specific Interference of Urokinase-type Plasminogen Activator Receptor and Matrix Metalloproteinase-9 Gene Expression Induced by Double-stranded RNA Results in Decreased Invasion, Tumor Growth, and Angiogenesis in Gliomas
Lakka, S. S.
Journal of Biological Chemistry 280
(12 April 2005); doi: 10.1074/jbc.M40852020015(S)-Hydroxyeicosatetraenoic Acid Induces Angiogenesis via Activation of PI3K-Akt-mTOR-S6K1 Signaling
Cancer Research
In Situ Photoactivation of a Caged Phosphotyrosine Peptide Derived from Focal Adhesion Kinase Temporarily Halts Lamellar Extension of Single Migrating Tumor Cells
Humphrey, D.
Journal of Biological Chemistry 280
(12 April 2005); doi: 10.1074/jbc.M502726200Breast cancer metastasis: markers and models
Weigelt, Britta, Peterse, Johannes L. and Van't veer, Laura J.
Nature Reviews Cancer 5 591 - 602
doi: 10.1038/nrc1670Cancer: the matrix is now in control
Comoglio, Paolo M and Trusolino, Livio
Nature Medicine 11 1156 - 1159
doi: 10.1038/nm1105-1156The CD44 Receptor Interacts with P-Glycoprotein to Promote Cell Migration and Invasion in Cancer
Cancer Research
Direct Interaction of the N-terminal Domain of Focal Adhesion Kinase with the N-terminal Transactivation Domain of p53
Golubovskaya, V. M.
Journal of Biological Chemistry 280
(25 April 2005); doi: 10.1074/jbc.M414172200Hypersialylation of B1 Integrins, Observed in Colon Adenocarcinoma, May Contribute to Cancer Progression by Up-regulating Cell Motility
Cancer Research
CD44 Attenuates Metastatic Invasion during Breast Cancer Progression
Cancer Research
Inhibition of Adhesion, Invasion, and Metastasis by Antibodies Targeting CEACAM6 (NCA-90) and CEACAM5 (Carcinoembryonic Antigen)
Cancer Res.
Requirement for Focal Adhesion Kinase in the Early Phase of Mammary Adenocarcinoma Lung Metastasis Formation
Cancer Research
RalA and RalB: Antagonistic Relatives in Cancer Cell Migration
Cancer Research
Bordetella Type III Secretion Modulates Dendritic Cell Migration Resulting in Immunosuppression and Bacterial Persistence
J Immunol.
A Secreted Form of ADAM9 Promotes Carcinoma Invasion through Tumor-Stromal Interactions
Cancer Research
c-Src-Mediated Phosphorylation of TRIP6 Regulates Its Function in Lysophosphatidic Acid-Induced Cell Migration
Mol. Cell. Biol.
Endogenous Osteonectin/SPARC/BM-40 Expression Inhibits MDA-MB-231 Breast Cancer Cell Metastasis
Cancer Research
Induction of Keratinocyte Migration via Transactivation of the Epidermal Growth Factor Receptor by the Antimicrobial Peptide LL-37
J Immunol.
Vascular Endothelial Cell Growth Factor Receptor 3-Mediated Activation of Lymphatic Endothelium Is Crucial for Tumor Cell Entry and Spread via Lymphatic Vessels
Cancer Research
Bcl-2 Promotes Invasion and Lung Metastasis by Inducing Matrix Metalloproteinase-2
Cancer Res.
Claudin-3 and Claudin-4 Expression in Ovarian Epithelial Cells Enhances Invasion and Is Associated with Increased Matrix Metalloproteinase-2 Activity
Cancer Research
Inhibition of Rho-Kinase Affects Astrocytoma Morphology, Motility, and Invasion through Activation of Rac1
Cancer Res.
Transendothelial Migration of Melanoma Cells Involves N-Cadherin-mediated Adhesion and Activation of the -Catenin Signaling Pathway
Qi, J.
Molecular Biology of the Cell 16
(15 June 2005); doi: 10.1091/mbc.E05-03-0186Lack of Telopeptides in Fibrillar Collagen I Promotes the Invasion of a Metastatic Breast Tumor Cell Line
Cancer Res.
The Journal of Immunology
Inhibition of Adhesion, Invasion, and Metastasis by Antibodies Targeting CEACAM6 (NCA-90) and CEACAM5 (Carcinoembryonic Antigen)
Cancer Res.
Activation of the Canonical Wnt Pathway during Genital Keratinocyte Transformation: A Model for Cervical Cancer Progression
Cancer Res.
The Journal of Immunology
Inhibition of Rho-Kinase Affects Astrocytoma Morphology, Motility, and Invasion through Activation of Rac1
Cancer Res.
Taking the lid off focal adhesions
J. Cell Sci.
Heat Shock Protein 60 Activates Cytokine-Associated Negative Regulator Suppressor of Cytokine Signaling 3 in T Cells: Effects on Signaling, Chemotaxis, and Inflammation
J Immunol.
Insulin-Like Growth Factor Binding Protein-5 Is a Target of Matrix Metalloproteinase-7: Implications for Epithelial-Mesenchymal Signaling
Cancer Research
Semaphorins command cells to move
Kruger, Robert P., Aurandt, Jennifer and Guan, Kun-Liang
Nature Reviews Molecular Cell Biology 6 789 - 800
doi: 10.1038/nrm1740Impact of Cutaneous IL-10 on Resident Epidermal Langerhans' Cells and the Development of Polarized Immune Responses
J Immunol.
A Network of PDZ-Containing Proteins Regulates T Cell Polarity and Morphology during Migration and Immunological Synapse Formation
Immunity
Rules of Recruitment for Th1 and Th2 Lymphocytes in Inflamed Liver: A Role for Alpha-4 Integrin and Vascular Adhesion Protein-1
Immunity
The melanocyte differentiation program predisposes to metastasis after neoplastic transformation
Gupta, Piyush B et al.
Nature Genetics 37 1047 - 1054
(4 September 2005); doi: 10.1038/ng1634The Journal of Immunology
Neutrophils Lacking Platelet-Endothelial Cell Adhesion Molecule-1 Exhibit Loss of Directionality and Motility in CXCR2-Mediated Chemotaxis
The Journal of Immunology
VEGF receptor-2 Y951 signaling and a role for the adapter molecule TSAd in tumor angiogenesis
Matsumoto, Taro et al.
The EMBO Journal 24
(6 October 0006); doi: 10.1038/sj.emboj.7600709A Specific Microdomain ("Glycosynapse 3") Controls Phenotypic Conversion and Reversion of Bladder Cancer Cells through GM3-mediated Interaction of 3 1 Integrin with CD9
Mitsuzuka, K.
Journal of Biological Chemistry 280
(24 August 2005); doi: 10.1074/jbc.M505630200A Non-Glycosaminoglycan-Binding Variant of CC Chemokine Ligand 7 (Monocyte Chemoattractant Protein-3) Antagonizes Chemokine-Mediated Inflammation
The Journal of Immunology
Syk Is Required for Monocyte/Macrophage Chemotaxis to CX3CL1 (Fractalkine)
The Journal of Immunology
The Androgen Derivative 5a -Androstane-3
,17-Diol Inhibits Prostate Cancer Cell Migration Through Activation of the Estrogen Receptor SubtypeCancer Res.
Quantum Proteolytic Activation of Chemokine CCL15 by Neutrophil Granulocytes Modulates Mononuclear Cell Adhesiveness
The Journal of Immunology
Involvement of the RASSF1A Tumor Suppressor Gene in Controlling Cell Migration
Cancer Research
Heat Shock Protein 70 Surface-Positive Tumor Exosomes Stimulate Migratory and Cytolytic Activity of Natural Killer Cells
Cancer Res.
Characteristics of NK Cell Migration Early after Vaccinia Infection
The Journal of Immunology
Rules of Recruitment for Th1 and Th2 Lymphocytes in Inflamed Liver: A Role for Alpha-4 Integrin and Vascular Adhesion Protein-1
Immunity
Macrophages Promote the Invasion of Breast Carcinoma Cells via a Colony-Stimulating Factor-1/Epidermal Growth Factor Paracrine Loop
Cancer Res.
CC Chemokine Ligand 19 Secreted by Mature Dendritic Cells Increases Naive T Cell Scanning Behavior and Their Response to Rare Cognate Antigen
The Journal of Immunology
Sphingosine 1-Phosphate Receptors Regulate Chemokine-Driven Transendothelial Migration of Lymph Node but Not Splenic T Cells
The Journal of Immunology
Cutting Edge: Egress of Newly Generated Plasma Cells from Peripheral Lymph Nodes Depends on B2 Integrin
The Journal of Immunology
Carcinoma Invasion and Metastasis: A Role for Epithelial-Mesenchymal Transition?
Cancer Res.
Cutting Edge: Chemoattractant Receptor-Homologous Molecule Expressed on TH2 Cells Plays a Restricting Role on IL-5 Production and Eosinophil Recruitment
The Journal of Immunology
Sphingosine-1-Phosphate Mediates Migration of Mature Dendritic Cells
The Journal of Immunology
The Fallacy of Epithelial Mesenchymal Transition in Neoplasia
Cancer Res.
Neutrophils Lacking Platelet-Endothelial Cell Adhesion Molecule-1 Exhibit Loss of Directionality and Motility in CXCR2-Mediated Chemotaxis
The Journal of Immunology
A Five-Amino-Acid Peptide Blocks Met- and Ron-Dependent Cell Migration
Cancer Res.
Syk Is Required for Monocyte/Macrophage Chemotaxis to CX3CL1 (Fractalkine)
The Journal of Immunology
A Mouse Model of Human Breast Cancer Metastasis to Human Bone
Proteolytic Processing Converts the Repelling Signal Sema3E into an Inducer of Invasive Growth and Lung Metastasis
Cancer Res.
Proteolytic maturation and activation of autotaxin (NPP2), a secreted metastasis-enhancing lysophospholipase D
Jansen, S.
Journal of Cell Science 118
(15 July 2005); doi: 10.1242/jcs.02438Migrating cancer stem cells — an integrated concept of malignant tumour progression
Brabletz, Thomas et al.
Nature Reviews Cancer 5 744 - 749
doi: 10.1038/nrc1694Protein Kinase A Gating of a Pseudopodial-located RhoA/ROCK/p38/NHE1 Signal Module Regulates Invasion in Breast Cancer Cell Lines
Cardone, R. A.
Molecular Biology of the Cell 16
(13 April 2005); doi: 10.1091/mbc.E04-10-0945The Runx2 Osteogenic Transcription Factor Regulates Matrix Metalloproteinase 9 in Bone Metastatic Cancer Cells and Controls Cell Invasion
Pratap, J.
Molecular and Cellular Biology 25
(1 October 2005); doi: 10.1128/MCB.25.19.8581-8591.2005RhoC is dispensable for embryogenesis and tumor initiation but essential for metastasis
Hakem, A.
Genes & Development 19
(1 September 2005); doi: 10.1101/gad.1310805Impact of Cutaneous IL-10 on Resident Epidermal Langerhans' Cells and the Development of Polarized Immune Responses
J Immunol.
Differential Induction of Glioblastoma Migration and Growth by Two Forms of Pleiotrophin
Lu, K. V.
Journal of Biological Chemistry 280
(2 June 2005); doi: 10.1074/jbc.M502614200Proliferation and invasion: Plasticity in tumor cells
Gao, C.-F.
Proceedings of the National Academy of Sciences 102
(26 July 2005); doi: 10.1073/pnas.0504367102Integrin Regulation by RhoA in Thymocytes
J Immunol.
The CD44 Receptor Interacts with P-Glycoprotein to Promote Cell Migration and Invasion in Cancer
Cancer Research
CD44 Attenuates Metastatic Invasion during Breast Cancer Progression
Cancer Researc
RalA and RalB: Antagonistic Relatives in Cancer Cell Migration
Cancer Research
15(S)-Hydroxyeicosatetraenoic Acid Induces Angiogenesis via Activation of PI3K-Akt-mTOR-S6K1 Signaling
Cancer Research
Insulin-Like Growth Factor Binding Protein-5 Is a Target of Matrix Metalloproteinase-7: Implications for Epithelial-Mesenchymal Signaling
Cancer Research
Endogenous Osteonectin/SPARC/BM-40 Expression Inhibits MDA-MB-231 Breast Cancer Cell Metastasis
Cancer Research
Claudin-3 and Claudin-4 Expression in Ovarian Epithelial Cells Enhances Invasion and Is Associated with Increased Matrix Metalloproteinase-2 Activity
Cancer Research
A Network of PDZ-Containing Proteins Regulates T Cell Polarity and Morphology during Migration and Immunological Synapse Formation
Immunity
The Journal of Immunology
The Journal of Immunology
The Journal of Immunology
Quantum Proteolytic Activation of Chemokine CCL15 by Neutrophil Granulocytes Modulates Mononuclear Cell Adhesiveness
The Journal of Immunology
The Journal of Immunology
CC Chemokine Ligand 19 Secreted by Mature Dendritic Cells Increases Naive T Cell Scanning Behavior and Their Response to Rare Cognate Antigen
The Journal of Immunology
Cutting Edge: Chemoattractant Receptor-Homologous Molecule Expressed on TH2 Cells Plays a Restricting Role on IL-5 Production and Eosinophil Recruitment
The Journal of Immunology