Subject archive
2010 Cancer
TGFβ signalling: a complex web in cancer progression
Ikushima, Hiroaki and Miyazono, Kohei
Nature Reviews Cancer 10 415 - 424
doi: 10.1038/nrc2853Regulation of miRNA expression by Src and contact normalization: effects on nonanchored cell growth and migration
Li, X et al.
Oncogene 28 4272 - 4283
(21 September 2009); doi: 10.1038/onc.2009.278Efficient cell migration requires global chromatin condensation
Gerlitz, G. and Bustin, M.
Journal of Cell Science 123
(1 July 2010); doi: 10.1242/jcs.058271Id2 Promotes Tumor Cell Migration and Invasion through Transcriptional Repression of Semaphorin 3F
Coma, S. et al.
Cancer Research 70
(1 May 2010); doi: 10.1158/0008-5472.CAN-09-3048hnRNP A2 Regulates Alternative mRNA Splicing of TP53INP2 to Control Invasive Cell Migration
Moran-jones, K. et al.
Cancer Research 69
(15 December 2009); doi: 10.1158/0008-5472.can-09-1852WNT11 Expression Is Induced by Estrogen-Related Receptor and -Catenin and Acts in an Autocrine Manner to Increase Cancer Cell Migration
Dwyer, M. A. et al.
Cancer Research 70
(15 November 2010); doi: 10.1158/0008-5472.CAN-10-0226Bmi1 is essential in Twist1-induced epithelial–mesenchymal transition
Yang, Muh-Hwa et al.
Nature Cell Biology 12 982 - 992
(5 September 2010); doi: 10.1038/ncb2099miR-200bc/429 cluster targets PLCγ1 and differentially regulates proliferation and EGF-driven invasion than miR-200a/141 in breast cancer
Uhlmann, S et al.
Oncogene 29 4297 - 4306
(31 May 2010); doi: 10.1038/onc.2010.201Cdc42-Interacting Protein 4 Promotes Breast Cancer Cell Invasion and Formation of Invadopodia through Activation of N-WASp
Pichot, C. S. et al.
Cancer Research 70
(1 November 2010); doi: 10.1158/0008-5472.CAN-09-4149Matrix Metalloproteinases Contribute Distinct Roles in Neuroendocrine Prostate Carcinogenesis, Metastasis, and Angiogenesis Progression
Littlepage, L. E. et al.
Cancer Research 70
(15 March 2010); doi: 10.1158/0008-5472.CAN-09-3515Apoptotic Death of Hematopoietic Tumor Cells through Potentiated and Sustained Adhesion to Fibronectin via VLA-4
Saito, Y. et al.
Journal of Biological Chemistry 285
(5 March 2010); doi: 10.1074/jbc.M109.027581Targeting the tumour vasculature: insights from physiological angiogenesis
Chung, Alicia S., Lee, John and Ferrara, Napoleone
Nature Reviews Cancer 10 505 - 514
doi: 10.1038/nrc2868The polarization of immune cells in the tumour environment by TGFβ
Flavell, Richard A., Sanjabi, Shomyseh, Wrzesinski, Stephen H. and Licona-limón, Paula
Nature Reviews Immunology 10 554 - 567
(9 July 2010); doi: 10.1038/nri2808The Eyes Absent phosphatase-transactivator proteins promote proliferation, transformation, migration, and invasion of tumor cells
Pandey, R N et al.
Oncogene 29 3715 - 3722
(26 April 2010); doi: 10.1038/onc.2010.122Modulation of Cellular Migration and Survival by c-Myc through the Downregulation of Urokinase (uPA) and uPA Receptor
Alfano, D. et al.
Molecular and Cellular Biology 30
(1 April 2010); doi: 10.1128/MCB.01442-09Visualizing extravasation dynamics of metastatic tumor cells
Stoletov, K. et al.
Journal of Cell Science 123
(1 July 2010); doi: 10.1242/jcs.069443Mutant p53 Drives Invasion by Promoting Integrin Recycling
Muller, Patricia A.J. et al.
Cell 139
(24 December 2009); doi: 10.1016/j.cell.2009.11.026Integrins and Mutant p53 on the Road to Metastasis
Selivanova, Galina and Ivaska, Johanna
Cell 139
(24 December 2009); doi: 10.1016/j.cell.2009.12.016A Complex between FAK, RACK1, and PDE4D5 Controls Spreading Initiation and Cancer Cell Polarity
Serrels, Bryan et al.
Current Biology 20
(22 June 2010); doi: 10.1016/j.cub.2010.04.042Cancer Dissemination—Lessons from Leukocytes
Madsen, Chris D. and Sahai, Erik
Developmental Cell 19
(20 July 2010); doi: 10.1016/j.devcel.2010.06.013Tumor Self-Seeding: Bidirectional Flow of Tumor Cells
Leung, Cheuk T. and Brugge, Joan S.
Cell 139
(24 December 2009); doi: 10.1016/j.cell.2009.12.013Ganglioside GD3 Enhances Adhesion Signals and Augments Malignant Properties of Melanoma Cells by Recruiting Integrins to Glycolipid-enriched Microdomains
Ohkawa, Y. et al.
Journal of Biological Chemistry 285
(27 August 2010); doi: 10.1074/jbc.M109.087791Merlin/NF2 Suppresses Tumorigenesis by Inhibiting the E3 Ubiquitin Ligase CRL4DCAF1 in the Nucleus
Li, Wei et al.
Cell 140
(19 February 2010); doi: 10.1016/j.cell.2010.01.029Suppression of Integrin 3 1 in Breast Cancer Cells Reduces Cyclooxygenase-2 Gene Expression and Inhibits Tumorigenesis, Invasion, and Cross-Talk to Endothelial Cells
Mitchell, K. et al.
Cancer Research 70
(1 August 2010); doi: 10.1158/0008-5472.CAN-09-4283MYC regulation of a "poor-prognosis" metastatic cancer cell state
Wolfer, A. et al.
Proceedings of the National Academy of Sciences 107
(23 February 2010); doi: 10.1073/pnas.0914203107COUP-TFII regulates tumor growth and metastasis by modulating tumor angiogenesis
Qin, J. et al.
Proceedings of the National Academy of Sciences 107
(23 February 2010); doi: 10.1073/pnas.0914619107GATA3 Inhibits Breast Cancer Metastasis through the Reversal of Epithelial-Mesenchymal Transition
Yan, W. et al.
Journal of Biological Chemistry 285
(30 April 2010); doi: 10.1074/jbc.M110.105262CUB Domain-Containing Protein 1, a Prognostic Factor for Human Pancreatic Cancers, Promotes Cell Migration and Extracellular Matrix Degradation
Miyazawa, Y. et al.
Cancer Research 70
(15 June 2010); doi: 10.1158/0008-5472.CAN-10-0220Migration or evasion
Melief, Cornelis
Nature Medicine 16 35 - 36
doi: 10.1038/nm0110-35Inositol-requiring enzyme 1 is a key regulator of angiogenesis and invasion in malignant glioma
Auf, G. et al.
Proceedings of the National Academy of Sciences 107
(31 August 2010); doi: 10.1073/pnas.0914072107A matrix metalloproteinase-1/protease activated receptor-1 signaling axis promotes melanoma invasion and metastasis
Blackburn, J S, Liu, I, Coon, C I and Brinckerhoff, C E
Oncogene 28 4237 - 4248
(7 September 2009); doi: 10.1038/onc.2009.272Her2 activates NF-κB and induces invasion through the canonical pathway involving IKKα
Merkhofer, E C, Cogswell, P and Baldwin, A S
Oncogene 29 1238 - 1248
(30 November 2009); doi: 10.1038/onc.2009.410Concurrent Suppression of Integrin 5, Radixin, and RhoA Phenocopies the Effects of miR-31 on Metastasis
Valastyan, S. et al.
Cancer Research 70
(15 June 2010); doi: 10.1158/0008-5472.CAN-10-0410Tumor-mediated liver X receptor-α activation inhibits CC chemokine receptor-7 expression on dendritic cells and dampens antitumor responses
Villablanca, Eduardo J et al.
Nature Medicine 16 98 - 105
(27 December 2009); doi: 10.1038/nm.2074YKL-40, a secreted glycoprotein, promotes tumor angiogenesis
Shao, R et al.
Oncogene 28 4456 - 4468
(21 September 2009); doi: 10.1038/onc.2009.292A Reaction-Diffusion Model of the Cadherin-Catenin System: A Possible Mechanism for Contact Inhibition and Implications for Tumorigenesis
Basan, Markus et al.
Biophysical Journal 98
(16 June 2010); doi: 10.1016/j.bpj.2010.03.051Regulation of Tumor Angiogenesis by EZH2
Lu, Chunhua et al.
Cancer Cell 18
(17 August 2010); doi: 10.1016/j.ccr.2010.06.016Integrin signalling adaptors: not only figurants in the cancer story
Cabodi, Sara, Del pilar camacho-leal, Maria, Di stefano, Paola and Defilippi, Paola
Nature Reviews Cancer 10 858 - 870
(24 November 2010); doi: 10.1038/nrc2967Fhit regulates invasion of lung tumor cells
Joannes, A et al.
Oncogene 29 1203 - 1213
(23 November 2009); doi: 10.1038/onc.2009.418I-BAR protein antagonism of endocytosis mediates directional sensing during guided cell migration
Quinones, G. A., Jin, J. and Oro, A. E.
The Journal of Cell Biology 189
(19 April 2010); doi: 10.1083/jcb.200910136Focal Adhesion Kinase Is Required for Intestinal Regeneration and Tumorigenesis Downstream of Wnt/c-Myc Signaling
Ashton, Gabrielle H. et al.
Developmental Cell 19
(17 August 2010); doi: 10.1016/j.devcel.2010.07.015In vivo magnetic enrichment and multiplex photoacoustic detection of circulating tumour cells
Galanzha, Ekaterina I. et al.
Nature Nanotechnology 4 855 - 860
(15 November 2009); doi: 10.1038/nnano.2009.333Ras-induced invasion and metastasis are regulated by a leukotriene B4 receptor BLT2-linked pathway
Kim, E-Y, Seo, J-M, Cho, K-J and Kim, J-H
Oncogene 29 1167 - 1178
(23 November 2009); doi: 10.1038/onc.2009.412ERα signaling through slug regulates E-cadherin and EMT
Ye, Y et al.
Oncogene 29 1451 - 1462
(18 January 2010); doi: 10.1038/onc.2009.433DRR drives brain cancer invasion by regulating cytoskeletal-focal adhesion dynamics
Le, P U et al.
Oncogene 29 4636 - 4647
(14 June 2010); doi: 10.1038/onc.2010.216Immune infiltration in human tumors: a prognostic factor that should not be ignored
Pagès, F et al.
Oncogene 29 1093 - 1102
(30 November 2009); doi: 10.1038/onc.2009.416mDia1 Targets v-Src to the Cell Periphery and Facilitates Cell Transformation, Tumorigenesis, and Invasion
Tanji, M. et al.
Molecular and Cellular Biology 30
(1 October 2010); doi: 10.1128/MCB.00197-10Pseudopodium-enriched atypical kinase 1 regulates the cytoskeleton and cancer progression
Wang, Y. et al.
Proceedings of the National Academy of Sciences 107
(15 June 2010); doi: 10.1073/pnas.0914776107MicroRNA-10b Promotes Migration and Invasion through KLF4 in Human Esophageal Cancer Cell Lines
Tian, Y. et al.
Journal of Biological Chemistry 285
(12 March 2010); doi: 10.1074/jbc.M109.062877A small-molecule inhibitor shows that pirin regulates migration of melanoma cells
Miyazaki, Isao et al.
Nature Chemical Biology 6 667 - 673
(15 August 2010); doi: 10.1038/nchembio.423DLC2 modulates angiogenic responses in vascular endothelial cells by regulating cell attachment and migration
Lin, Y et al.
Oncogene 29 3010 - 3016
(8 March 2010); doi: 10.1038/onc.2010.54p21-activated kinase 4 regulates ovarian cancer cell proliferation, migration, and invasion and contributes to poor prognosis in patients
Siu, M. K. Y. et al.
Proceedings of the National Academy of Sciences 107
(26 October 2010); doi: 10.1073/pnas.0907481107Eicosanoids and cancer
Wang, Dingzhi and Dubois, Raymond N.
Nature Reviews Cancer 10 181 - 193
(19 February 2010); doi: 10.1038/nrc2809Prostaglandin E2/EP1 Signaling Pathway Enhances Intercellular Adhesion Molecule 1 (ICAM-1) Expression and Cell Motility in Oral Cancer Cells
Yang, S.-F. et al.
Journal of Biological Chemistry 285
(24 September 2010); doi: 10.1074/jbc.M110.108183Vascular endothelial platelet endothelial cell adhesion molecule 1 (PECAM-1) regulates advanced metastatic progression
Delisser, H. et al.
Proceedings of the National Academy of Sciences 107
(26 October 2010); doi: 10.1073/pnas.1004654107Generation of clonal zebrafish lines and transplantable hepatic tumors
Mizgirev, Igor and Revskoy, Sergei
Nature Protocols 5 383 - 394
(11 February 2010); doi: 10.1038/nprot.2010.8Myosin light chain kinase mediates transcellular intravasation of breast cancer cells through the underlying endothelial cells: a three-dimensional FRET study
Khuon, S. et al.
Journal of Cell Science 123
(1 February 2010); doi: 10.1242/jcs.053793miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis
Ma, Li et al.
Nature Cell Biology 12 247 - 256
(21 February 2010); doi: 10.1038/ncb2024CAV1 Inhibits Metastatic Potential in Melanomas through Suppression of the Integrin/Src/FAK Signaling Pathway
Trimmer, C. et al.
Cancer Research 70
(1 October 2010); doi: 10.1158/0008-5472.CAN-10-0900Implication of Metastasis Suppressor NM23-H1 in Maintaining Adherens Junctions and Limiting the Invasive Potential of Human Cancer Cells
Boissan, M. et al.
Cancer Research 70
(1 October 2010); doi: 10.1158/0008-5472.CAN-10-1887NFAT3 transcription factor inhibits breast cancer cell motility by targeting the Lipocalin 2 gene
Fougère, M et al.
Oncogene 29 2292 - 2301
(25 January 2010); doi: 10.1038/onc.2009.499Translational control in cancer
Silvera, Deborah, Formenti, Silvia C. and Schneider, Robert J.
Nature Reviews Cancer 10 254 - 266
doi: 10.1038/nrc2824Integrin–TGF-β crosstalk in fibrosis, cancer and wound healing
Margadant, Coert and Sonnenberg, Arnoud
EMBO reports 11 97 - 105
(15 January 2010); doi: 10.1038/embor.2009.276Gain of miR-151 on chromosome 8q24.3 facilitates tumour cell migration and spreading through downregulating RhoGDIA
Ding, Jie et al.
Nature Cell Biology 12 390 - 399
(21 March 2010); doi: 10.1038/ncb2039