Subject archive
2009 Adhesion
Mechanically Activated Integrin Switch Controls 5 1 Function
Friedland, J. C., Lee, M. H. and Boettiger, D.
Science 323
(30 January 2009); doi: 10.1126/science.1168441Src-Induced Disassembly of Adherens Junctions Requires Localized Phosphorylation and Degradation of the Rac Activator Tiam1
Woodcock, Simon A. et al.
Molecular Cell 33
(13 March 2009); doi: 10.1016/j.molcel.2009.02.012Clustering of 5 1 integrins determines adhesion strength whereas v 3 and talin enable mechanotransduction
Roca-cusachs, P., Gauthier, N. C., Del rio, A. and Sheetz, M. P.
Proceedings of the National Academy of Sciences 106
(22 September 2009); doi: 10.1073/pnas.0902818106Connexin 43 regulates epicardial cell polarity and migration in coronary vascular development
Rhee, D. Y. et al.
Development 136
(15 September 2009); doi: 10.1242/dev.032334Talin phosphorylation by Cdk5 regulates Smurf1-mediated talin head ubiquitylation and cell migration CMC
Huang, Cai et al.
Nature Cell Biology 11 624 - 630
(12 April 2009); doi: 10.1038/ncb1868Multiparametric analysis of focal adhesion formation by RNAi-mediated gene knockdown CMC
Winograd-katz, S. E., Itzkovitz, S., Kam, Z. and Geiger, B.
The Journal of Cell Biology 186
(10 August 2009); doi: 10.1083/jcb.200901105The cell adhesion molecules Echinoid and Friend of Echinoid coordinate cell adhesion and cell signaling to regulate the fidelity of ommatidial rotation in the Drosophila eye
Fetting, J. L., Spencer, S. A. and Wolff, T.
Development 136
(1 October 2009); doi: 10.1242/dev.038422Traction Dynamics of Filopodia on Compliant Substrates
Chan, C. E. and Odde, D. J.
Science 322
(12 December 2008); doi: 10.1126/science.1163595A Mek1–Mek2 heterodimer determines the strength and duration of the Erk signal
Catalanotti, Federica et al.
Nature Structural & Molecular Biology 16 294 - 303
(15 February 2009); doi: 10.1038/nsmb.1564Numb regulates cell–cell adhesion and polarity in response to tyrosine kinase signalling
Wang, Zezhou, Sandiford, Shelley, Wu, Chenggang and Li, Shawn Shun-Cheng
The EMBO Journal 28 2360 - 2373
(16 July 2009); doi: 10.1038/emboj.2009.190An integrin αvβ3–c-Src oncogenic unit promotes anchorage-independence and tumor progression
Desgrosellier, Jay S et al.
Nature Medicine 15 1163 - 1169
(6 September 2009); doi: 10.1038/nm.2009The Structure of the N-Terminus of Kindlin-1: A Domain Important for αIIbβ3 Integrin Activation CMC
Goult, Benjamin T. et al.
Journal of Molecular Biology
(3 October 2009); doi: 10.1016/j.jmb.2009.09.061Neuronal Thy-1 induces astrocyte adhesion by engaging syndecan-4 in a cooperative interaction with v 3 integrin that activates PKC and RhoA
Avalos, A. M. et al.
Journal of Cell Science 122
(1 October 2009); doi: 10.1242/jcs.034827The structure of an integrin/talin complex reveals the basis of inside-out signal transduction CMC
Anthis, Nicholas J et al.
The EMBO Journal
(1 October 2009); doi: 10.1038/emboj.2009.287Force-induced cell polarisation is linked to RhoA-driven microtubule-independent focal-adhesion sliding
Goldyn, A. M. et al.
Journal of Cell Science 122
(15 October 2009); doi: 10.1242/jcs.054866Dynamic conformational changes in the FERM domain of FAK are involved in focal-adhesion behavior during cell spreading and motility
Papusheva, E. et al.
Journal of Cell Science 122
(1 March 2009); doi: 10.1242/jcs.028738Quantitative proteomics identifies a Dab2/integrin module regulating cell migration
Teckchandani, A. et al.
The Journal of Cell Biology 186
(13 July 2009); doi: 10.1083/jcb.200812160Nedd9/Hef1/Cas-L mediates the effects of environmental pollutants on cell migration and plasticity
Bui, L -C et al.
Oncogene 28 3642 - 3651
(3 August 2009); doi: 10.1038/onc.2009.224MEK5/ERK5 Signaling Modulates Endothelial Cell Migration and Focal Contact Turnover
Spiering, D. et al.
Journal of Biological Chemistry 284
(11 September 2009); doi: 10.1074/jbc.M109.042911Src Homology 2-Domain Containing Leukocyte-Specific Phosphoprotein of 76 kDa Is Mandatory for TCR-Mediated Inside-Out Signaling, but Dispensable for CXCR4-Mediated LFA-1 Activation, Adhesion, and Migration of T Cells
Horn, J. et al.
The Journal of Immunology 183
(1 November 2009); doi: 10.4049/jimmunol.0900649Integrins in cell migration - the actin connection
Vicente-manzanares, M., Choi, C. K. and Horwitz, A. R.
Journal of Cell Science 122
(15 January 2009); doi: 10.1242/jcs.018564Role of Rap1B and Tumor Suppressor PTEN in the Negative Regulation of Lysophosphatidic Acid-induced Migration by Isoproterenol in Glioma Cells
Malchinkhuu, E. et al.
Molecular Biology of the Cell
(28 October 2009); doi: 10.1091/mbc.E09-08-0692FAK alters invadopodia and focal adhesion composition and dynamics to regulate breast cancer invasion
Chan, K. T., Cortesio, C. L. and Huttenlocher, A.
The Journal of Cell Biology 185
(20 April 2009); doi: 10.1083/jcb.200809110WNT/TCF Signaling through LEF1 and HOXB9 Mediates Lung Adenocarcinoma Metastasis
Nguyen, Don X. et al.
Cell 138
(10 July 2009); doi: 10.1016/j.cell.2009.04.030Spontaneous phosphoinositide 3-kinase signaling dynamics drive spreading and random migration of fibroblasts
Weiger, M. C. et al.
Journal of Cell Science 122
(1 February 2009); doi: 10.1242/jcs.037564Tetraspanin CD151 regulates RhoA activation and the dynamic stability of carcinoma cell-cell contacts
Johnson, J. L., Winterwood, N., Demali, K. A. and Stipp, C. S.
Journal of Cell Science 122
(1 July 2009); doi: 10.1242/jcs.045997Actin-Based Protrusions: Promoters or Inhibitors of Cancer Invasion?
Machesky, Laura M. and Tang, Hao Ran
Cancer Cell 16
(7 July 2009); doi: 10.1016/j.ccr.2009.06.009Syndecan-4 regulates ADAMTS-5 activation and cartilage breakdown in osteoarthritis
Echtermeyer, Frank et al.
Nature Medicine 15 1072 - 1076
(16 August 2009); doi: 10.1038/nm.1998Inhibition of Tumor Cell Growth, Invasion, and Metastasis by EXEL-2880 (XL880, GSK1363089), a Novel Inhibitor of HGF and VEGF Receptor Tyrosine Kinases
Qian, F. et al.
Cancer Research 69
(15 October 2009); doi: 10.1158/0008-5472.CAN-08-4889Regulation of Platelet-derived Growth Factor Receptor Function by Integrin-associated Cell Surface Transglutaminase
Zemskov, E. A. et al.
Journal of Biological Chemistry 284
(12 June 2009); doi: 10.1074/jbc.M109.010769Integrin 9 1 mediates enhanced cell migration through nitric oxide synthase activity regulated by Src tyrosine kinase
Gupta, S. K. and Vlahakis, N. E.
Journal of Cell Science 122
(15 June 2009); doi: 10.1242/jcs.041632Dynamic adhesions and MARCKS in melanoma cells
Estrada-bernal, A., Gatlin, J. C., Sunpaweravong, S. and Pfenninger, K. H.
Journal of Cell Science 122
(1 July 2009); doi: 10.1242/jcs.047860Cyfip1 Is a Putative Invasion Suppressor in Epithelial Cancers
Silva, Jose M. et al.
Cell 137
(12 June 2009); doi: 10.1016/j.cell.2009.04.013Adhesion signaling - crosstalk between integrins, Src and Rho
Huveneers, S. and Danen, E. H. J.
Journal of Cell Science 122
(15 April 2009); doi: 10.1242/jcs.039446An adhesion-independent, aPKC-dependent function for cadherins in morphogenetic movements
Seifert, K. et al.
Journal of Cell Science 122
(15 July 2009); doi: 10.1242/jcs.042796N- and E-cadherins in Xenopus are specifically required in the neural and non-neural ectoderm, respectively, for F-actin assembly and morphogenetic movements
Nandadasa, S. et al.
Development 136
(15 April 2009); doi: 10.1242/dev.031203Leukocyte adhesion deficiency-III is caused by mutations in KINDLIN3 affecting integrin activation
Svensson, Lena et al.
Nature Medicine 15 306 - 312
(22 February 2009); doi: 10.1038/nm.1931Outside-In Signal Transmission by Conformational Changes in Integrin Mac-1
Lefort, C. T. et al.
The Journal of Immunology
(28 October 2009); doi: 10.4049/jimmunol.0900983The structural basis of integrin-linked kinase-PINCH interactions
Chiswell, B. P. et al.
Proceedings of the National Academy of Sciences 105
(30 December 2008); doi: 10.1073/pnas.0811415106Roles of Specific Membrane Lipid Domains in EGF Receptor Activation and Cell Adhesion Molecule Stabilization in a Developing Olfactory System
Gibson, Nicholas J., Tolbert, Leslie P., Oland, Lynne A. and Chédotal, Alain
PLoS ONE 4
(29 September 2009); doi: 10.1371/journal.pone.0007222Cell polarity triggered by cell-cell adhesion via E-cadherin
Desai, R. A. et al.
Journal of Cell Science 122
(1 April 2009); doi: 10.1242/jcs.028183Changes in Retinoblastoma Cell Adhesion Associated with Optic Nerve Invasion
Laurie, N. et al.
Molecular and Cellular Biology
(28 September 2009); doi: 10.1128/MCB.00374-09Transcriptional Repression of Epithelial Cell Adhesion Molecule Contributes to p53 Control of Breast Cancer Invasion
Sankpal, N. V. et al.
Cancer Research 69
(20 January 2009); doi: 10.1158/0008-5472.CAN-08-2708RalA suppresses early stages of Ras-induced squamous cell carcinoma progression
Sowalsky, A G et al.
Oncogene
(5 October 2009); doi: 10.1038/onc.2009.307Focal Adhesion Kinase Modulates Cell Adhesion Strengthening via Integrin Activation
Michael, K. E. et al.
Molecular Biology of the Cell 20
(1 May 2009); doi: 10.1091/mbc.E08-01-0076Hepatic tumor–stroma crosstalk guides epithelial to mesenchymal transition at the tumor edge
Van zijl, F et al.
Oncogene 28 4022 - 4033
(31 August 2009); doi: 10.1038/onc.2009.253The actin-bundling protein fascin is overexpressed in colorectal adenomas and promotes motility in adenoma cells in vitro
Qualtrough, D et al.
British Journal of Cancer 101 1124 - 1129
(8 September 2009); doi: 10.1038/sj.bjc.6605286Tipping the Balance: Robustness of Tip Cell Selection, Migration and Fusion in Angiogenesis
Bentley, Katie et al.
PLoS Computational Biology 5
(30 October 2009); doi: 10.1371/journal.pcbi.1000549