Cell Migration Gateway http://www.cellmigration.org Nature Publishing Group en © 2008 Nature Publishing Group Cell Migration Gateway 1747-7883 © 2008 Nature Publishing Group permissions@nature.com Cell Migration Gateway http://www.nature.com/includes/rj_globnavimages/cmg_update_logo.gif http://www.cellmigration.org Notch signalling: The long road to the aorta http://www.cellmigration.org/cmg_update/2008/080701/full/cmg073.shtml Notch signalling drives the specification of endothelial precursors in somites and directs their migration toward the dorsal aorta, thus resulting in its three-dimensional assembly. Notch signalling: The long road to the aorta

Cell Migration Gateway (2008). doi:10.1038/cmg073

Author: Kim Baumann

Notch signalling drives the specification of endothelial precursors in somites and directs their migration toward the dorsal aorta, thus resulting in its three-dimensional assembly.

]]> Notch signalling: The long road to the aorta Kim Baumann doi:10.1038/cmg073 Cell Migration Gateway (2008) 2008-07-03 Cell Migration Gateway 2008-07-03 Featured Articles Actin nucleation: To CAP it off http://www.cellmigration.org/cmg_update/2008/080701/full/cmg074.shtml The capping protein favours actin nucleation by the actin-related protein-2/3 complex thus increasing the rate of actin-based motility. Actin nucleation: To CAP it off

Cell Migration Gateway (2008). doi:10.1038/cmg074

Author: Kim Baumann

The capping protein favours actin nucleation by the actin-related protein-2/3 complex thus increasing the rate of actin-based motility.

]]> Actin nucleation: To CAP it off Kim Baumann doi:10.1038/cmg074 Cell Migration Gateway (2008) 2008-07-03 Cell Migration Gateway 2008-07-03 Featured Articles Metastasis: Regressing to self-renewal http://www.cellmigration.org/cmg_update/2008/080701/full/nrc2423.shtml Metastasis: Regressing to self-renewal

Nature Reviews Cancer 8, 483 (2008). doi:10.1038/nrc2423

Author: Gemma K. Alderton

]]> Metastasis: Regressing to self-renewal Gemma K. Alderton doi:10.1038/nrc2423 Nature Reviews Cancer 8, 483 (2008) 2008-06-12 Cell Migration Gateway 2008-06-12 8 7 Research Highlights 483 483 Cancer genetics: Looking at the big picture http://www.cellmigration.org/cmg_update/2008/080701/full/nrg2405.shtml Cancer genetics: Looking at the big picture

Nature Reviews Genetics 9, 498 (2008). doi:10.1038/nrg2405

Author: Patrick Goymer

]]> Cancer genetics: Looking at the big picture Patrick Goymer doi:10.1038/nrg2405 Nature Reviews Genetics 9, 498 (2008) 2008-06-10 Cell Migration Gateway 2008-06-10 9 7 Research Highlights 498 499 Cell morphology: Breaking the spatial code http://www.cellmigration.org/cmg_update/2008/080701/full/nrm2433.shtml Cell morphology: Breaking the spatial code

Nature Reviews Molecular Cell Biology 9, 500 (2008). doi:10.1038/nrm2433

Author: Ekat Kritikou

]]> Cell morphology: Breaking the spatial code Ekat Kritikou doi:10.1038/nrm2433 Nature Reviews Molecular Cell Biology 9, 500 (2008) 2008-06-11 Cell Migration Gateway 2008-06-11 9 7 Research Highlights 500 500 Moving towards a Better Understanding of Chemotaxis http://dx.doi.org/10.1016/j.cub.2008.04.048 Moving towards a Better Understanding of Chemotaxis

Current Biology 18, (2008). doi:10.1016/j.cub.2008.04.048

Authors: L STEPHENS, L MILNE & P HAWKINS

]]> Moving towards a Better Understanding of Chemotaxis L STEPHENS L MILNE P HAWKINS doi:10.1016/j.cub.2008.04.048 Current Biology 18, (2008) Cell Migration Gateway 18 11 Research Library Sdf1/Cxcr4 signaling controls the dorsal migration of endodermal cells during zebrafish gastrulation http://dx.doi.org/10.1242/dev.020107 Sdf1/Cxcr4 signaling controls the dorsal migration of endodermal cells during zebrafish gastrulation

Development , (2008). doi:10.1242/dev.020107

Authors: T. Mizoguchi, H. Verkade, J. K. Heath, A. Kuroiwa & Y. Kikuchi

]]> Sdf1/Cxcr4 signaling controls the dorsal migration of endodermal cells during zebrafish gastrulation T. Mizoguchi H. Verkade J. K. Heath A. Kuroiwa Y. Kikuchi doi:10.1242/dev.020107 Development , (2008) Cell Migration Gateway Research Library PTEN functions to 'prioritize' chemotactic cues and prevent 'distraction' in migrating neutrophils http://dx.doi.org/10.1038/ni.1623 Leukocytes sense and move in the direction of chemoattractants. Kubes and colleagues show that the phosphatase PTEN is required by migrating neutrophils to 'prioritize' multiple chemoattractant signals, as are encountered in infected tissues. PTEN functions to 'prioritize' chemotactic cues and prevent 'distraction' in migrating neutrophils

Nature Immunology 9, 743 (2008). doi:10.1038/ni.1623

Authors: Bryan Heit, Stephen M Robbins, Charlene M Downey, Zhiwen Guan, Pina Colarusso, B Joan Miller, Frank R Jirik & Paul Kubes

]]> PTEN functions to 'prioritize' chemotactic cues and prevent 'distraction' in migrating neutrophils Bryan Heit Stephen M Robbins Charlene M Downey Zhiwen Guan Pina Colarusso B Joan Miller Frank R Jirik Paul Kubes doi:10.1038/ni.1623 Nature Immunology 9, 743 (2008) 2008-06-08 Cell Migration Gateway 2008-06-08 9 7 Research Library 743 752 Cancer reveals cruel trick http://dx.doi.org/10.1038/news.2008.887 Some tumours may stimulate the growth of distant cancers within the body. Cancer reveals cruel trick

Nature News , (2008). doi:10.1038/news.2008.887

Author: Heidi Ledford

Some tumours may stimulate the growth of distant cancers within the body.

]]> Cancer reveals cruel trick Heidi Ledford doi:10.1038/news.2008.887 Nature News , (2008) 2008-06-12 Cell Migration Gateway 2008-06-12 News Consortium July Update http://www.cellmigration.org/cmcnews/cmcnews.shtml Actin treadmilling: G-actin diffusion or local recycling? Signalling in space: Coupling at the plasma membrane. Consortium July Update

Consortium Updates (2008). Article

Actin treadmilling: G-actin diffusion or local recycling? Signalling in space: Coupling at the plasma membrane.

]]> Consortium July Update Consortium Updates (2008) Cell Migration Gateway News Breaking down EMT http://www.cellmigration.org/cmg_update/2008/080701/full/ncb0708-757.shtml Epithelial–mesenchymal transition, in which epithelial cells lose their polarity and become motile mesenchymal cells, occurs during development and marks a key step in tumour progression towards metastasis. Most studies of this process have focused on the disassembly of adherens junctions, but regulation of basement membrane breakdown by a pathway involving RhoA and microtubules may be equally important.