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Welcome to the May 2008 Cell Migration Update, your one-stop resource for news, highlights and research on cell migration.

FEATURED ARTICLES

Specially written Editor's reviews of the hottest new articles

Mammary development: Collective migration without protrusions

Mammary branching morphogenesis results from the transition of a bilayered epithelium into a multilayered epithelium, followed by a mechanism of collective migration where cells do not form leading protrusions.

Kim Baumann Original research paper: Dev. Cell 14, 570-581 (2008)

Differential signalling: For quiescence or for migration?

Angiogenesis and vascular quiescence are regulated by the Tie2 receptor tyrosine kinase and its ligand Angiopoietin-1 through the activation of different signalling cascades at cell–cell and cell–matrix contacts.

Kim Baumann Original research paper: Nat. Cell Biol. 10, 513-526 (2008)

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RESEARCH HIGHLIGHTS

Synopses of important recent articles

Cell migration: Group voyage

Collective cell migration is regulated by an evolutionarily conserved cascade that involves the Jun N-terminal kinase (JNK) signalling pathway.

Ekat KritikouNature Reviews Molecular Cell Biology 9, 346 (2008)

Oncogenes: Sibling rivalry explained

The use of genetically engineered mice has shed light on the distinct effects of proteins encoded by the oncogenes KRAS and NRAS on differentiation and tumorigenesis in colonic epithelium.

Isobel BarryNature Reviews Cancer 8, 324 - 325 (2008)

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NEWS

The latest news selected from the CMC, Nature News and journals from the Nature family

Consortium Update

Consortium May Update

Integrin activation: A height complex.
Multicolour compositional imaging: Adhesions revealed.

James Watson's genome sequenced at high speed

New-generation technology takes just four months and costs a fraction of old method.


CELL MIGRATION KNOWLEDGEBASE

From Zamir & Geiger 2001; J. Cell Sc. 114:3583-90. Reproduced with permission from the Company of Biologists.

Visit the Cell Migration Knowledgebase for the latest cell migration protein database entries.

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CONSORTIUM ACTIVITIES

From Nalbant et al. 2004; Science 305:1615-19. Reprinted with permission from AAAS.

Find out more about the Consortium activities, and the latest Consortium Updates.