Welcome to the May 2013 Cell Migration Update, your one-stop resource for news, highlights and research on cell migration.
CELL MIGRATION @ NATURE.COM
A comprehensive library of the latest research related to cell migration
PKA-induced dimerization of the RhoGAP DLC1 promotes its inhibition of tumorigenesis and metastasis
Standfirst
Nature Communications
FEATURED ARTICLES
Editor's reviews of the hottest new articles
HER2 in the DOCK over breast cancer metastasis
Standfirst
Activation of the Rac GEF DOCK1 downstream of HER2 increases Rac activity to promote the migration of breast cancer cells and facilitate breast cancer metastasis in vivo.
Original research paper: Proc. Natl Acad. Sci. USA, published online 16 April 2013
Two-leg trip to invasion
Standfirst
A novel pathway involving HIF-1α, Notch, ADAM12 and HB-EGF promotes the formation of invadopodia in hypoxia.
Original research paper: J. Cell Biol. 201, 279–292 (2013)
CONSORTIUM NEWS
The latest news from the CMC
β1 integrin’s importance in invadopodia
Standfirst
Other CMC Publications
Standfirst
CELL MIGRATION KNOWLEDGEBASE
Visit the Cell Migration Knowledgebase for the latest cell migration protein database entries.
Now new and improved.
CONSORTIUM ACTIVITIES
Find out more about the Consortium activities, and the latest Consortium Updates.
RESEARCH HIGHLIGHTS
Synopses of important recent articles

Ovarian cancer: Driving force
Standfirst
Actomyosin-mediated contractility in ovarian cancer cells induces mesothelial cells to de-adhere and move away, facilitating penetration of the mesothelial barrier during metastasis.
Nature Reviews Cancer 11, 538 - 539 (2011)
Innate immunity: Neutrophil U-turn fans the flames
Standfirst
The expression of junctional adhesion molecule C in endothelial cells is required to prevent reverse transendothelial migration of neutrophils.
Nature Reviews Immunology 11, 498 (2011)
