Featured Articles
Each month we showcase exciting new cell migration articles from the literature.
-
January 2012
The path to cofilin freedom: from phosphorylation to pH
Standfirst
Recruitment of the sodium–hydrogen exchanger NHE1 to phosphorylated cortactin in invadopodia disrupts cortactin–cofilin binding by locally increasing the pH, thereby releasing active cofilin to generate free barbed ends of actin.
Original research paper: J. Cell Biol. 195, 903–920 (2011)