November 2011

• Deconstructing the skin: cytoarchitectural determinants of epidermal morphogenesis

  Cory L. Simpson, Dipal M. Patel, Kathleen J. Green
  Nature Reviews Molecular Cell Biology
  doi: 10.1038/nrm3175

  Abstract

• Integrin adhesion and force coupling are independently regulated by localized PtdIns(4,5)2 synthesis

  Kyle R Legate, Seiichiro Takahashi, Navid Bonakdar, Ben Fabry, David Boettiger, Roy Zent, Reinhard Fässler
  The EMBO Journal
  doi: 10.1038/emboj.2011.332

  Abstract

• New insights into the T cell synapse from single molecule techniques

  Michael L. Dustin, David Depoil
  Nature Reviews Immunology
  doi: 10.1038/nri3066

  Abstract

• Integrated morphodynamic signalling of the mammary gland

  Nikolce Gjorevski, Celeste M. Nelson
  Nature Reviews Molecular Cell Biology
  doi: 10.1038/nrm3168

  Abstract

• The 'invisible hand': regulation of RHO GTPases by RHOGDIs

  Rafael Garcia-Mata, Etienne Boulter, Keith Burridge
  Nature Reviews Molecular Cell Biology
  doi: 10.1038/nrm3153

  Abstract

• Lysophosphatidic acid and sphingosine-1-phosphate promote morphogenesis and block invasion of prostate cancer cells in three-dimensional organotypic models

  V Härmä, M Knuuttila, J Virtanen, T Mirtti, P Kohonen, P Kovanen, A Happonen, S Kaewphan, I Ahonen, O Kallioniemi, R Grafström, J Lötjönen, M Nees
  Oncogene
  doi: 10.1038/onc.2011.396

  Abstract

• Loss of EBP50 stimulates EGFR activity to induce EMT phenotypic features in biliary cancer cells

  A Clapéron, N Guedj, M Mergey, D Vignjevic, C Desbois-Mouthon, M Boissan, B Saubaméa, V Paradis, C Housset, L Fouassier
  Oncogene
  doi: 10.1038/onc.2011.334

  Abstract

• TRPV4 mediates tumor-derived endothelial cell migration via arachidonic acid-activated actin remodeling

  A Fiorio Pla, H L Ong, K T Cheng, A Brossa, B Bussolati, T Lockwich, B Paria, L Munaron, I S Ambudkar
  Oncogene
  doi: 10.1038/onc.2011.231

  Abstract

• A biosensor generated via high-throughput screening quantifies cell edge Src dynamics

  Akash Gulyani, Eric Vitriol, Richard Allen, Jianrong Wu, Dmitriy Gremyachinskiy, Steven Lewis, Brian Dewar, Lee M Graves, Brian K Kay, Brian Kuhlman, Tim Elston, Klaus M Hahn
  Nature Chemical Biology
  doi: 10.1038/nchembio.585

  Abstract

• Coronin 1A promotes a cytoskeletal-based feedback loop that facilitates Rac1 translocation and activation

  Antonio Castro-Castro, Virginia Ojeda, María Barreira, Vincent Sauzeau, Inmaculada Navarro-Lérida, Olivia Muriel, José R Couceiro, Felipe X Pimentel-Muíños, Miguel A del Pozo, Xosé R Bustelo
  The EMBO Journal
  doi: 10.1038/emboj.2011.310

  Abstract