Featured Articles
Each month we showcase exciting new cell migration articles from the literature.
-
November 2011
SHARPINing up on integrin regulation
Standfirst
The cytosolic protein SHARPIN functions as an endogenous inhibitor of β1-integrins by binding directly to integrin α-subunits and thereby preventing recruitment of talin and kindlin to the integrin.
Original research paper: Nat. Cell Biol., published online 25 September 2011
