September 2011

• Lpd depletion reveals that SRF specifies radial versus tangential migration of pyramidal neurons

  Elaine M. Pinheiro, Zhigang Xie, Amy L. Norovich, Marina Vidaki, Li-Huei Tsai, Frank B. Gertler
  Nature Cell Biology
  doi: 10.1038/ncb2292

  Abstract

• Manipulation of host membranes by bacterial effectors

  Hyeilin Ham, Anju Sreelatha, Kim Orth
  Nature Reviews Microbiology
  doi: 10.1038/nrmicro2602

  Abstract

• Dynamic molecular processes mediate cellular mechanotransduction

  Brenton D. Hoffman, Carsten Grashoff, Martin A. Schwartz
  Nature
  doi: 10.1038/nature10316

  Abstract

• SPARC Promotes Cathepsin B-Mediated Melanoma Invasiveness through a Collagen I/α2β1 Integrin Axis

  María R Girotti, Marisol Fernández, Juan A López, Emilio Camafeita, Elmer A Fernández, Juan P Albar, Lorena G Benedetti, María P Valacco, Rolf A Brekken, Osvaldo L Podhajcer, Andrea S Llera
  Journal of Investigative Dermatology
  doi: 10.1038/jid.2011.239

  Abstract

• Cross-regulation between protein L-isoaspartyl O-methyltransferase and ERK in epithelial mesenchymal transition of MDA-MB-231 cells

  Jiyeon Ryu, Jihyeok Song, Jieun Heo, Yongwoo Jung, Sang-Jin Lee, Sungyoul Hong, Jae Youl Cho
  Acta Pharmacologica Sinica
  doi: 10.1038/aps.2011.94

  Abstract

• Increased expression of the large GTPase dynamin 2 potentiates metastatic migration and invasion of pancreatic ductal carcinoma

  R D Eppinga, E W Krueger, S G Weller, L Zhang, H Cao, M A McNiven
  Oncogene
  doi: 10.1038/onc.2011.329

  Abstract

• Loss of EBP50 stimulates EGFR activity to induce EMT phenotypic features in biliary cancer cells

  A Clapéron, N Guedj, M Mergey, D Vignjevic, C Desbois-Mouthon, M Boissan, B Saubaméa, V Paradis, C Housset, L Fouassier
  Oncogene
  doi: 10.1038/onc.2011.334

  Abstract

• FHL2 expression in peritumoural fibroblasts correlates with lymphatic metastasis in sporadic but not in HNPCC-associated colon cancer

  Lucia Gullotti, Jacqueline Czerwitzki, Jutta Kirfel, Peter Propping, Nils Rahner, Verena Steinke, Philip Kahl, Christoph Engel, Roland Schüle, Reinhard Buettner, Nicolaus Friedrichs
  Laboratory Investigation
  doi: 10.1038/labinvest.2011.109

  Abstract

• Expression of Snail and Slug in renal cell carcinoma: E-cadherin repressor Snail is associated with cancer invasion and prognosis

  Shuji Mikami, Ken-Ichi Katsube, Mototsugu Oya, Masaru Ishida, Takeo Kosaka, Ryuichi Mizuno, Makio Mukai, Yasunori Okada
  Laboratory Investigation
  doi: 10.1038/labinvest.2011.111

  Abstract

• Detection of focal adhesion kinase activation at membrane microdomains by fluorescence resonance energy transfer

  Jihye Seong, Mingxing Ouyang, Taejin Kim, Jie Sun, Po-Chao Wen, Shaoying Lu, Yue Zhuo, Nicholas M. Llewellyn, David D. Schlaepfer, Jun-Lin Guan, Shu Chien, Yingxiao Wang
  Nature Communications
  doi: 10.1038/ncomms1414

  Abstract

• Metastasis-associated phosphatase PRL-2 regulates tumor cell migration and invasion

  Y Wang, J S Lazo
  Oncogene
  doi: 10.1038/onc.2011.281

  Abstract

• The interaction between caveolin-1 and Rho-GTPases promotes metastasis by controlling the expression of alpha5-integrin and the activation of Src, Ras and Erk

  E Arpaia, H Blaser, M Quintela-Fandino, G Duncan, H S Leong, A Ablack, S C Nambiar, E F Lind, J Silvester, C K Fleming, A Rufini, M W Tusche, A Brüstle, P S Ohashi, J D Lewis, T W Mak
  Oncogene
  doi: 10.1038/onc.2011.288

  Abstract

• p140Cap suppresses the invasive properties of highly metastatic MTLn3-EGFR cells via impaired cortactin phosphorylation

  L Damiano, S E Le Dévédec, P Di Stefano, D Repetto, R Lalai, H Truong, J L Xiong, E H Danen, K Yan, F J Verbeek, E De Luca, F Attanasio, R Buccione, E Turco, B van de Water, P Defilippi
  Oncogene
  doi: 10.1038/onc.2011.257

  Abstract

• The SRC-associated protein CUB Domain-Containing Protein-1 regulates adhesion and motility

  C H Benes, G Poulogiannis, L C Cantley, S P Soltoff
  Oncogene
  doi: 10.1038/onc.2011.262

  Abstract

• Recognition of CD146 as an ERM-binding protein offers novel mechanisms for melanoma cell migration

  Y Luo, C Zheng, J Zhang, D Lu, J Zhuang, S Xing, J Feng, D Yang, X Yan
  Oncogene
  doi: 10.1038/onc.2011.244

  Abstract

• Phosphoinositide 3-kinase signaling is critical for ErbB3-driven breast cancer cell motility and metastasis

  T Smirnova, Z N Zhou, R J Flinn, J Wyckoff, P J Boimel, M Pozzuto, S J Coniglio, J M Backer, A R Bresnick, J S Condeelis, N E Hynes, J E Segall
  Oncogene
  doi: 10.1038/onc.2011.275

  Abstract

• Semaphorin 5A and plexin-B3 regulate human glioma cell motility and morphology through Rac1 and the actin cytoskeleton

  X Li, J W S Law, A Y W Lee
  Oncogene
  doi: 10.1038/onc.2011.256

  Abstract

• The 'ins' and 'outs' of podosomes and invadopodia: characteristics, formation and function

  Danielle A. Murphy, Sara A. Courtneidge
  Nature Reviews Molecular Cell Biology
  doi: 10.1038/nrm3141

  Abstract

• Epithelial-to-mesenchymal transition in prostate cancer: paradigm or puzzle?

  Jones T. Nauseef, Michael D. Henry
  Nature Reviews Urology
  doi: 10.1038/nrurol.2011.85

  Abstract

• TRPV4 mediates tumor-derived endothelial cell migration via arachidonic acid-activated actin remodeling

  A Fiorio Pla, H L Ong, K T Cheng, A Brossa, B Bussolati, T Lockwich, B Paria, L Munaron, I S Ambudkar
  Oncogene
  doi: 10.1038/onc.2011.231

  Abstract

• Rack1 promotes epithelial cell–cell adhesion by regulating E-cadherin endocytosis

  G Swaminathan, C A Cartwright
  Oncogene
  doi: 10.1038/onc.2011.242

  Abstract

• RasGRF suppresses Cdc42-mediated tumour cell movement, cytoskeletal dynamics and transformation

  Fernando Calvo, Victoria Sanz-Moreno, Lorena Agudo-Ibáñez, Fredrik Wallberg, Erik Sahai, Christopher J. Marshall, Piero Crespo
  Nature Cell Biology
  doi: 10.1038/ncb2271

  Abstract

• Ezrin is key regulator of Src-induced malignant phenotype in three-dimensional environment

  L Heiska, M Melikova, F Zhao, I Saotome, A I McClatchey, O Carpén
  Oncogene
  doi: 10.1038/onc.2011.207

  Abstract

• A biosensor generated via high-throughput screening quantifies cell edge Src dynamics

  Akash Gulyani, Eric Vitriol, Richard Allen, Jianrong Wu, Dmitriy Gremyachinskiy, Steven Lewis, Brian Dewar, Lee M Graves, Brian K Kay, Brian Kuhlman, Tim Elston, Klaus M Hahn
  Nature Chemical Biology
  doi: 10.1038/nchembio.585

  Abstract

• Cancer cells in epithelial-to-mesenchymal transition and tumor-propagating–cancer stem cells: distinct, overlapping or same populations

  S Floor, W C G van Staveren, D Larsimont, J E Dumont, C Maenhaut
  Oncogene
  doi: 10.1038/onc.2011.184

  Abstract

• miR-296 regulation of a cell polarity–cell plasticity module controls tumor progression

  V Vaira, A Faversani, T Dohi, M Montorsi, C Augello, S Gatti, G Coggi, D C Altieri, S Bosari
  Oncogene
  doi: 10.1038/onc.2011.209

  Abstract

• The tumor-suppressor gene ARHI (DIRAS3) suppresses ovarian cancer cell migration through inhibition of the Stat3 and FAK/Rho signaling pathways

  D B Badgwell, Z Lu, K Le, F Gao, M Yang, G K Suh, J-J Bao, P Das, M Andreeff, W Chen, Y Yu, A A Ahmed, W S-L Liao, R C Bast
  Oncogene
  doi: 10.1038/onc.2011.213

  Abstract

• Coronin 1A promotes a cytoskeletal-based feedback loop that facilitates Rac1 translocation and activation

  Antonio Castro-Castro, Virginia Ojeda, María Barreira, Vincent Sauzeau, Inmaculada Navarro-Lérida, Olivia Muriel, José R Couceiro, Felipe X Pimentel-Muíños, Miguel A del Pozo, Xosé R Bustelo
  The EMBO Journal
  doi: 10.1038/emboj.2011.310

  Abstract