Research Highlights
This is an archive of research highlights generated between June 2005 and August 2011. These highlights summarize and put into context must-read papers related to cell migration.
May 2011
Synaptogenesis: Switching to learn
Standfirst
The actin-capping, spectrin-binding molecule β-adducin and its fly homologue HTS have key roles in coordinating synapse assembly and disassembly.
Nature Reviews Neuroscience 12, 248 - 249 (2011)doi:10.1038/nrn3034
Immunology: Bad company
Standfirst
Inhibiting the recruitment of macrophages to tumours increases sensitivity to chemotherapy through a mechanism involving the activation of CD8+ T cells.
Nature Reviews Cancer 11, 311 (2011)doi:10.1038/nrc3056
Archaea: Archaea shape up
Standfirst
Reports on the discovery of an actin orthologue and several related proteins in archaea, providing insight into the formation of cell shape.
Nature Reviews Microbiology 9, 312 - 313 (2011)doi:10.1038/nrmicro2568
Autoimmune disease: New drug target for MS?
Standfirst
Therapeutically targeting repulsive guidance molecule a (RGMa), a membrane-bound axon guidance molecule, reduces the invasion of inflammatory cells to the central nervous system and attenuates clinical signs of disease in a mouse model of multiple sclerosis.
Nature Reviews Drug Discovery 10, 339 (2011)doi:10.1038/nrd3450