Research Highlights
This is an archive of research highlights generated between June 2005 and August 2011. These highlights summarize and put into context must-read papers related to cell migration.
April 2011
Molecular motors: Moving in a new direction
Standfirst
Cin8, a budding yeast Kinesin-5, is a bidirectional motor.
Nature Reviews Molecular Cell Biology 12, 208 - 209 (2011)doi:10.1038/nrm3090
Development: Budding potential
Standfirst
Outlines a novel model of mouse limb bud growth that can chart cell movements and patterns of regulatory gene expression in time and space.
Nature Reviews Genetics 12, 230 (2011)doi:10.1038/nrg2974
Tumorigenesis: Wound-up tumours
Standfirst
Two papers describe how wounds 'induce' tumorigenic stem cells to emigrate from their niches.
Nature Reviews Cancer 11, 235 (2011)doi:10.1038/nrc3043
Tumour immunology: Pro-metastatic TReg cells get RANKed
Standfirst
CD4+ regulatory T cells promote mammary tumour metastasis by expressing RANKL.
Nature Reviews Immunology 11, 236 - 237 (2011)doi:10.1038/nri2962