April 2011

• A Perspective on Cancer Cell Metastasis

  Chaffer, C. L. and Weinberg, R. A.
  Science
  (25 March 2011); doi: 10.1126/science.1203543

  Abstract

• Blood Vessel Tubulogenesis Requires Rasip1 Regulation of GTPase Signaling

  Xu, Ke et al.
  Developmental Cell
  (10 March 2011); doi: 10.1016/j.devcel.2011.02.010

  Abstract

• Proneural Transcription Factors Regulate Different Steps of Cortical Neuron Migration through Rnd-Mediated Inhibition of RhoA Signaling

  Pacary, Emilie et al.
  Neuron
  (1 March 2011); doi: 10.1016/j.neuron.2011.02.018

  Abstract

• Force nanoscopy of living cells

  Müller, Daniel J. and Dufrêne, Yves F.
  Current Biology
  (1 March 2011); doi: 10.1016/j.cub.2011.01.046

  Abstract

• The Formin DAD Domain Plays Dual Roles in Autoinhibition and Actin Nucleation

  Gould, Christopher J. et al.
  Current Biology
  (8 March 2011); doi: 10.1016/j.cub.2011.01.047

  Abstract

• ERK-MAPK Drives Lamellipodia Protrusion by Activating the WAVE2 Regulatory Complex CMC

  Mendoza, M. C. et al.
  Molecular Cell
  (18 March 2011); doi: 10.1016/j.molcel.2011.02.031

  Abstract

• Kindlin-3-mediated signaling from multiple integrin classes is required for osteoclast-mediated bone resorption

  Schmidt, S. et al.
  The Journal of Cell Biology
  (7 March 2011); doi: 10.1083/jcb.201007141

  Abstract

• Calpain-6, a microtubule-stabilizing protein, regulates Rac1 activity and cell motility through interaction with GEF-H1

  Tonami, K. et al.
  Journal of Cell Science
  (15 April 2011); doi: 10.1242/jcs.072561

  Abstract

• 'White wave' analysis of epithelial scratch wound healing reveals how cells mobilise back from the leading edge in a myosin-II-dependent fashion

  Matsubayashi, Y., Razzell, W. and Martin, P.
  Journal of Cell Science
  (1 April 2011); doi: 10.1242/jcs.080853

  Abstract

• Asymmetric Mbc, active Rac1 and F-actin foci in the fusion-competent myoblasts during myoblast fusion in Drosophila

  Haralalka, S. et al.
  Development
  (15 April 2011); doi: 10.1242/dev.057653

  Abstract

• Asymmetric localisation of cytokine mRNA is essential for JAK/STAT activation during cell invasiveness

  Van de Bor, V. et al.
  Development
  (1 April 2011); doi: 10.1242/dev.056184

  Abstract

• β1 integrins regulate fibroblast chemotaxis through control of N-WASP stability

  King, Samantha J et al.
  The EMBO Journal
  (22 March 2011); doi: 10.1038/emboj.2011.82

  Abstract

• Structural basis for the slow dynamics of the actin filament pointed end

  Narita, Akihiro, Oda, Toshiro and Maéda, Yuichiro
  The EMBO Journal
  (4 March 2011); doi: 10.1038/emboj.2011.48

  Abstract

• The Dual Effect of Rac2 on PLD2 Regulation that Explains Both the Onset and Termination of Chemotaxis

  Peng, H.-J. et al.
  Molecular and Cellular Biology
  (28 March 2011); doi: 10.1128/MCB.01348-10

  Abstract

• Kinesin-5, a mitotic microtubule-associated motor protein, modulates neuronal migration

  Falnikar, A., Tole, S. and Baas, P. W.
  Molecular Biology of the Cell
  (16 March 2011); doi: 10.1091/mbc.E10-11-0905

  Abstract

• A Direct Interaction Between the Large GTPase Dynamin2 and FAK Regulate Focal Adhesion Dynamics in Response to Active Src

  Wang, Y., Cao, H., Chen, J. and McNiven, M. A.
  Molecular Biology of the Cell
  (16 March 2011); doi: 10.1091/mbc.E10-09-0785

  Abstract

• RhoA is dispensable for skin development, but crucial for contraction and directed migration of keratinocytes

  Jackson, B. et al.
  Molecular Biology of the Cell
  (1 March 2011); doi: 10.1091/mbc.E09-10-0859

  Abstract

• Mechanism of a concentration-dependent switch between activation and inhibition of ARP2/3 complex by coronin

  Liu, S.-L., Needham, K. M., May, J. R. and Nolen, B. J.
  Journal of Biological Chemistry
  (21 March 2011); doi: 10.1074/jbc.M111.219964

  Abstract

• Osteopontin Undergoes Polymerization in Vivo and Gains Chemotactic Activity for Neutrophils Mediated by Integrin α9β1

  Nishimichi, N. et al.
  Journal of Biological Chemistry
  (1 April 2011); doi: 10.1074/jbc.M110.189258

  Abstract

• Calpain-mediated Proteolysis of Paxillin Negatively Regulates Focal Adhesion Dynamics and Cell Migration

  Cortesio, C. L. et al.
  Journal of Biological Chemistry
  (25 March 2011); doi: 10.1074/jbc.M110.187294

  Abstract

• Pancreatic cancer cells respond to type I collagen by inducing Snail expression to promote membrane type 1-matrix metalloproteinase dependent collagen invasion

  Shields, M. A. et al.
  Journal of Biological Chemistry
  (2 February 2011); doi: 10.1074/jbc.M110.195628

  Abstract

• RACK1 Regulates VEGF/Flt1-mediated Cell Migration via Activation of a PI3K/Akt Pathway

  Wang, F. et al.
  Journal of Biological Chemistry
  (18 March 2011); doi: 10.1074/jbc.M110.165605

  Abstract

• Disrupted-in-Schizophrenia 1-mediated axon guidance involves TRIO-RAC-PAK small GTPase pathway signaling

  Chen, S.-Y., Huang, P.-H. and Cheng, H.-J.
  Proceedings of the National Academy of Sciences
  (21 March 2011); doi: 10.1073/pnas.1018128108

  Abstract

• Dendritic cell chemotaxis in 3D under defined chemokine gradients reveals differential response to ligands CCL21 and CCL19

  Haessler, U., Pisano, M., Wu, M. and Swartz, M. A.
  Proceedings of the National Academy of Sciences
  (21 March 2011); doi: 10.1073/pnas.1014920108

  Abstract

• Cell-ECM traction force modulates endogenous tension at cell-cell contacts

  Maruthamuthu, V., Sabass, B., Schwarz, U. S. and Gardel, M. L.
  Proceedings of the National Academy of Sciences
  (22 March 2011); doi: 10.1073/pnas.1011123108

  Abstract

• Glass-like dynamics of collective cell migration

  Angelini, T. E. et al.
  Proceedings of the National Academy of Sciences
  (22 March 2011); doi: 10.1073/pnas.1010059108

  Abstract

• Sphingosine 1-Phosphate-Induced Motility and Endocytosis of Dendritic Cells Is Regulated by SWAP-70 through RhoA

  Ocana-Morgner, C. et al.
  The Journal of Immunology
  (18 March 2011); doi: 10.4049/jimmunol.1003461

  Abstract

• Macrophage Migration Inhibitory Factor and CD74 Regulate Macrophage Chemotactic Responses via MAPK and Rho GTPase

  Fan, H. et al.
  The Journal of Immunology
  (16 March 2011); doi: 10.4049/jimmunol.1003713

  Abstract

• Hematopoietic Lineage Cell-Specific Protein 1 Functions in Concert with the Wiskott-Aldrich Syndrome Protein To Promote Podosome Array Organization and Chemotaxis in Dendritic Cells

  Klos Dehring, D. A. et al.
  The Journal of Immunology
  (11 March 2011); doi: 10.4049/jimmunol.1003102

  Abstract

• CLIP-170 and IQGAP1 Cooperatively Regulate Dendrite Morphology

  Swiech, L. et al.
  Journal of Neuroscience
  (23 March 2011); doi: 10.1523/JNEUROSCI.6582-10.2011

  Abstract

• mTORC1 and mTORC2 regulate EMT, motility and metastasis of colorectal cancer via RhoA and Rac1 signaling pathways

  Gulhati, P. et al.
  Cancer Research
  (23 March 2011); doi: 10.1158/0008-5472.CAN-10-4058

  Abstract

• Rho Kinase Phosphorylation Promotes Ezrin-Mediated Metastasis in Hepatocellular Carcinoma

  Chen, Y. et al.
  Cancer Research
  (1 March 2011); doi: 10.1158/0008-5472.CAN-09-4683

  Abstract

• Keratocyte Lamellipodial Protrusion Is Characterized by a Concave Force-Velocity Relation

  Heinemann, Fabian, Doschke, Holger and Radmacher, Manfred
  Biophysical Journal
  (16 March 2011); doi: 10.1016/j.bpj.2011.01.063

  Abstract

• On the Mechanical Stabilization of Filopodia

  Zidovska, Alexandra and Sackmann, Erich
  Biophysical Journal
  (16 March 2011); doi: 10.1016/j.bpj.2011.01.069

  Abstract

• Three-Dimensional Traction Force Microscopy: A New Tool for Quantifying Cell-Matrix Interactions

  Franck, Christian et al.
  PLoS ONE
  (29 March 2011); doi: 10.1371/journal.pone.0017833

  Abstract

• Dissecting Regulatory Networks of Filopodia Formation in a Drosophila Growth Cone Model

  Gonçalves-Pimentel, Catarina et al.
  PLoS ONE
  (28 March 2011); doi: 10.1371/journal.pone.0018340

  Abstract

• Endocytosis Regulates Cell Soma Translocation and the Distribution of Adhesion Proteins in Migrating Neurons

  Shieh, Jennifer C. et al.
  PLoS ONE
  (22 March 2011); doi: 10.1371/journal.pone.0017802

  Abstract

• Crystal Structure of a Coiled-Coil Domain from Human ROCK I

  Tu, Daqi et al.
  PLoS ONE
  (21 March 2011); doi: 10.1371/journal.pone.0018080

  Abstract

• A role for actin arcs in the leading-edge advance of migrating cells

  Burnette, Dylan T. et al.
  Nature Cell Biology
  (20 March 2011); doi: 10.1038/ncb2205

  Abstract

• Drosophila katanin is a microtubule depolymerase that regulates cortical-microtubule plus-end interactions and cell migration

  Zhang, Dong et al.
  Nature Cell Biology
  (6 March 2011); doi: 10.1038/ncb2206

  Abstract