Research Highlights
This is an archive of research highlights generated between June 2005 and August 2011. These highlights summarize and put into context must-read papers related to cell migration.
March 2011
Regeneration: A regenerative medicine
Standfirst
Microtubule stabilization using paclitaxel reduces scarring and promotes axon regeneration after spinal cord injury.
Nature Reviews Neuroscience 12, 123 (2011)doi:10.1038/nrn3002
Development: New rules of attraction
Standfirst
The CXC-chemokine receptors CXCR4 and CXCR7 have non-redundant but interacting functions in response to CXC-chemokine ligand 12 during neuronal migration in CNS development.
Nature Reviews Neuroscience 12, 124 - 125 (2011)doi:10.1038/nrn3001
Microrna: Micromanaging CD44
Standfirst
CD44 is identified as a key target for the miR-34a-microRNA-mediated inhibition of prostate tumour progression.
Nature Reviews Cancer 11, 156 (2011)doi:10.1038/nrc3024
Prostate cancer: Prostate quartet
Standfirst
Four genes are identified as drivers of prostate adenocarcinoma progression and as a signature for predicting recurrence and metastasis of this type of cancer.
Nature Reviews Cancer 11, 159 (2011)doi:10.1038/nrc3029
Cancer: Re-educating tumour-associated macrophages
Standfirst
Histidine-rich glycoprotein decreases the expression of placental growth factor in tumour-associated macrophages to mediate antitumour and antimetastatic effects.
Nature Reviews Drug Discovery 10, 177 (2011)doi:10.1038/nrd3399