Featured Articles
Each month we showcase exciting new cell migration articles from the literature.
January 2011
Collective cell migration: Keeping together
Standfirst
A DDR1–PAR3/PAR6 complex recruits RHOE to reduce actomyosin activity at sites of cell contact within groups of migrating cells.
Original research paper: Nat Cell Biol 13, 49-58 (2011)
mTORC2 brings up the rear
Standfirst
During neutrophil chemotaxis, mTORC2 regulates the synthesis of cAMP, thereby antagonizing RHOA to induce myosin II-mediated retraction of the cell rear.
Original research paper: Dev. Cell 19, 845-857 (2011)