Featured Articles
Each month we showcase exciting new cell migration articles from the literature.
November 2010
Cell migration: A new move for SUMO
Standfirst
PIAS3, an E3 SUMO ligase, interacts with Rac1, promoting its SUMOylation and thereby enhancing its activation and, consequently, cell migration.
Original research paper: Nature Cell Biol., published online 10 October 2010
Microtubules: Caught in the act
Standfirst
ErbB2-induced repression of GSK3β activity in migrating breast carcinoma cells enables APC and CLASP to localize to the plasma membrane to recruit the spectraplakin ACF7, which mediates microtubule capture.
Original research paper: Proc. Natl Acad. Sci. USA, published online 11 October 2010