Research Highlights
This is an archive of research highlights generated between June 2005 and August 2011. These highlights summarize and put into context must-read papers related to cell migration.
June 2010
Tumour suppression: Double act
Standfirst
Loss of expression of the homeobox gene HOXA9 correlates with more aggressive breast cancer phenotypes, perhaps owing to the ability of HOXA9 to regulate expression of BRCA1.
Nature Reviews Cancer 10, 382 - 383 (2010)doi:10.1038/nrc2858
Metastasis: How do you spell metastasis?
Standfirst
The entire genome sequence of biopsy samples from a basal-like breast cancer primary tumour and brain metastasis identifies some of the genetic changes evident in the metastases that were also present in a subset of cells from the primary tumour.
Nature Reviews Cancer 10, 384 - 385 (2010)doi:10.1038/nrc2859
Cell signalling: Regulation and crosstalk
Standfirst
Molecular links between cell polarity, cell division and cell fate.
Nature Reviews Molecular Cell Biology 11, 390 (2010)doi:10.1038/nrm2915