Research Highlights
This is an archive of research highlights generated between June 2005 and August 2011. These highlights summarize and put into context must-read papers related to cell migration.
March 2010
Tumorigenesis: Bad neighbours
Standfirst
Cellular interactions are important for tumour development.
Nature Reviews Cancer 10, 159 (2010)doi:10.1038/nrc2821
Tumour microenvironment: Macrophages lead the way
Standfirst
Local paracrine signalling contributes to the transition of normal macrophages to tumour-associated macrophages (TAMs) that facilitate invasion, angiogenesis and tumour growth.
Nature Reviews Cancer 10, 162 - 163 (2010)doi:10.1038/nrc2816
Signal transduction: Integrin's new partner
Standfirst
Integrins interact with Gα13 protein-coupled receptors and mediate signalling to SRC and RHOA, thereby regulating cell spreading.
Nature Reviews Molecular Cell Biology 11, 164 (2010)doi:10.1038/nrm2856