Research Highlights
Short, accessible highlights that summarize and put into context must-read papers related to cell migration.
December 2009
Bacterial pathogenesis: A 'hijacked' regulatory mechanism
Standfirst
Listeria monocytogenes maintains its cell-to-cell spread by regulating actin polymerization of host cells.
Nature Reviews Microbiology 7, 760 (2009)doi:10.1038/nrmicro2252
Psychiatric disorders: DISC1 drives development through girdin
Standfirst
A new study reveals that the interaction between the actin-binding protein girdin and DISC1 has a role in the regulation of neuronal growth and migration in the postnatal and adult hippocampus.
Nature Reviews Neuroscience 10, 763 (2009)doi:10.1038/nrn2746
Lipid signaling: LPA's ways of actin
Standfirst
Lysophosphatidic acid (LPA) controls actin dynamics indirectly, through cell surface receptor-mediated signaling, and directly, by binding and inhibiting villin.
Lipidomics Gateway (28 October 2009)doi:10.1038/lipidmaps.2009.29
