Research Highlights
Short, accessible highlights that summarize and put into context must-read papers related to cell migration.
September 2009
Metastasis: Influencing bad behaviour
Standfirst
CD4+ T cells have been shown to promote metastasis by influencing macrophages in a mouse model of breast cancer.
Nature Reviews Cancer 9, 609 (2009)doi:10.1038/nrc2720
Metastasis: Route master
Standfirst
A new study reports that the Wnt pathway may be important for lung adenocarcinoma metastasis to the brain and bone.
Nature Reviews Cancer 9, 610 - 611 (2009)doi:10.1038/nrc2721
Migration: Exchange to migrate
Standfirst
The activation of GABAARs (γ-aminobutyric acid type A receptors) in NG2 cells – a group of glial precursors – triggers a Ca2+ signalling pathway that involves the reversal of Na+-Ca2+ exchanger 1 (NCX1) activity and is required for the migration of NG2 cells during development.
Nature Reviews Neuroscience 10, 622 - 623 (2009)doi:10.1038/nrn2706
