Featured Articles
Each month we showcase exciting new cell migration articles from the literature.
September 2009
GTPase activation at the leading edge: Advancing technologies
Standfirst
The use of 'computational multiplexing' and a photoactivatable version of Rac1 has revealed that RhoA is activated concomitantly to cell advancement, that Rac1 and Cdc42 activation is delayed compared to that of RhoA, and that Rac1 inhibits RhoA.
Original research papers: Nature, published online 19 August 2009.
Focal adhesion assembly: New relationships from an siRNA screen
Standfirst
A high-throughput siRNA screen aimed at understanding how molecular pathways affect the assembly of focal adhesions (FAs) reveals major correlations between distinct FA morphological features.
Original research paper: J. Cell Biol. 186, 423-436 (2009)