Featured Articles
Each month we showcase exciting new cell migration articles from the literature.
April 2009
Protein kinase D1: A (sling)shot against directed migration
Standfirst
PKD1 inhibits the activation of cofilin at the cell front via slingshot phosphatases, thus blocking the formation of free F-actin barbed ends and directed cell migration.
Original research paper: Nat. Cell Biol., published online 29 March 2009
Mek kinases: Dimers dim MAPK signaling
Standfirst
Mek1–Mek2 heterodimer formation is essential for Erk-mediated attenuation of the Raf-Mek-Erk signaling cascade.
Original research paper: Nat. Struct. Mol. Biol. 16, 294-303 (2009)