Research Highlights
Short, accessible highlights that summarize and put into context must-read papers related to cell migration.
March 2009
Lymphocyte migration: 'Guided' tour of the brain
Standfirst
A recent study reveals that T cells are readily recruited to the brain during Toxoplasma gondii infection and migrate along infection-induced reticular fibres.
Nature Reviews Immunology 9, 146 - 147 (2009)doi:10.1038/nri2509
Genetics: The importance of networking
Standfirst
Researchers have applied the construction of genetic networks to linking genotypes to phenotypes in mice, thus highlighting the potential of this approach for identifying genes with key roles in disease-related phenotypes.
Nature Reviews Cancer 9, 149 (2009)doi:10.1038/nrc2612
Tumour immunology: Multi-tasking by STAT3
Standfirst
Three studies have investigated whether STAT3 activity might promote cytokine-induced tumour growth in tumour cells, but in immune cells it might modulate cytokine production to inhibit tumour-specific immune responses or inflammation.
Nature Reviews Immunology 9, 149 (2009)doi:10.1038/nri2517
