Featured Articles
Each month we showcase exciting new cell migration articles from the literature.
December 2008
Wnt/
-catenin and FGF signalling: Maintaining group polarityStandfirst
Interaction between the Wnt/
-catenin and fibroblast growth factor (FGF) signalling pathways results in their mutually exclusive activation, which is required for the polarised distribution of the chemokine receptors that control coordinated directional migration.Original research paper: Dev. Cell 15, 749-761 (2008)
Epithelial cell detachment: Up to PAR
Standfirst
The serine/threonine kinase PAR1 regulates epithelial apical-basal polarity and is required for cell-cell junction remodelling, which allows border cell detachment and migration during Drosophila melanogaster oogenesis.
Original research paper: Curr. Biol. 18, 1659-1667 (2008)