Research Highlights
Short, accessible highlights that summarize and put into context must-read papers related to cell migration.
November 2008
Development: A force to be reckoned with
Standfirst
An apoptotic force enables dorsal closure during Drosophila melanogaster development, thus defining a new role for apoptotic forces in tissue sculpting and development.
Nature Reviews Molecular Cell Biology 9, 824 - 825 (2008)doi:10.1038/nrm2539
Membrane trafficking: Recycling integrins
Standfirst
Two studies now provide insights into the regulation of integrin trafficking by the Rab family of small GTPases in both cell migration and cytokinesis.
Nature Reviews Molecular Cell Biology 9, 826 - 827 (2008)doi:10.1038/nrm2537
Metastasis: A sweet sabre promotes cell invasion
Standfirst
A new study shows that specific forms of the extracellular matrix component chondroitin sulphate contribute to tumour cell invasion.
Nature Reviews Cancer 8, 828 - 829 (2008)doi:10.1038/nrc2532
Metastasis: Preparing the soil
Standfirst
A new pathway involving Toll-like receptor 4 has been shown to enhance metastasis to the lungs by promoting the accumulation of macrophages and haematopoietic progenitors.
Nature Reviews Cancer 8, 832 - 833 (2008)doi:10.1038/nrc2525
