Featured Articles
Each month we showcase exciting new cell migration articles from the literature.
November 2008
Myosin-II: An extending tail
Standfirst
Whereas myosin-IIA forms actin cables in regions of protrusion, myosin IIB is confined to the rear where its activation induces the formation of an extended tail that supports directional migration.
Original research paper: J Cell Biol. 183, 543-554 (2008)
Adhesion dynamics: Actin and microtubules get along with ACF7
Standfirst
The microtubule-actin crosslinking protein ACF7 coordinates microtubule growth along filamentous actin towards focal adhesions (FAs). Microtubule targeting to FAs is required for FA turnover and cell migration.
Original research paper: Cell 135, 137-148 (2008)