Featured Articles
Each month we showcase exciting new cell migration articles from the literature.
October 2008
Actin branching: Coronin 1B vs. cortactin
Standfirst
Coronin 1B antagonizes the actin branch stabilizing activity of cortactin by inducing the dissociation of the actin-related protein-2/3 (ARP2/3) complex from actin branches, thus regulating actin dynamics at the lamellipodia.
Original research paper: Cell 134, 828-842 (2008)
Cell adhesion: Talin shifts cell spreading into high gear
Standfirst
The cytoskeletal protein talin functions as a molecular clutch that links the contracting actin cytoskeleton to extracellular matrix-bound integrins.
Original research paper: Nature Cell Biol. 10, 1062-1068 (2008)