Research Highlights
Short, accessible highlights that summarize and put into context must-read papers related to cell migration.
September 2008
Angiogenesis: VEGFR3 joins the crew
Standfirst
Two studies have highlighted the potential of targeting vascular endothelial growth factor receptor 3 (VEGF3) — which affects endothelial sprouting — as a treatment for tumour growth and metastasis.
Nature Reviews Cancer 8, 660 - 661 (2008)doi:10.1038/nrc2446
Axon guidance: Pioneering exit
Standfirst
Axon-axon interactions between neurons with a similar path were shown to guide axonal growth cone pathfinding in the Zebrafish retinotectal system.
Nature Reviews Neuroscience 9, 660 - 661 (2008)doi:10.1038/nrn2485
Biomarkers: Finding the needle in the haystack
Standfirst
Detecting the presence of tumour-derived microRNAs (miRNAs) in plasma or serum has been shown to be an effective strategy for cancer detection.
Nature Reviews Cancer 8, 659 (2008)doi:10.1038/nrc2474
In brief: Cell adhesion
Standfirst
Researchers have elucidated the signalling pathways that lead to the formation of the actin-rich adhesion structures called podosomes.
Nature Reviews Molecular Cell Biology 9, 665 (2008)doi:10.1038/nrm2480
