Research Highlights
Short, accessible highlights that summarize and put into context must-read papers related to cell migration.
April 2008
Metastasis: A metastatic switch
Standfirst
The upregulation of SATB1, which controls both chromatin structure and the expression of multiple genomic loci, correlates with aggressive tumour phenotypes and reduced patient survival.
Nature Reviews Cancer 8, 248 - 249 (2008)doi:10.1038/nrc2359
Stem cells: MicroRNAs promote differentiation
Standfirst
Two new studies show that specific microRNAs are important for triggering cell differentiation - a process that is crucial for both normal development and the avoidance of cancer.
Nature Reviews Genetics 9, 251 (2008)doi:10.1038/nrg2352
