Featured Articles
Each month we showcase exciting new cell migration articles from the literature.
March 2008
Platelets aggregation: Kindlin' integrin activation
Standfirst
The platelet protein Kindlin-3 activates integrins by binding to their cytoplasmic β tails upon blood vessel injury, thus allowing efficient platelet aggregation and preventing blood loss.
Original research paper: Nature Medicine, published online 17 February (2008)
Germ cell migration: CXCR7 clearing the way
Standfirst
The zebrafish receptor CXCR7 sequesters SDF-1a, allowing the formation of an active chemoattractant gradient that is necessary for the correct migration of primordial germ cells.
Original research paper: Cell 132, 463-473 (2008)