Research Highlights
Short, accessible highlights that summarize and put into context must-read papers related to cell migration.
December 2007
Tumour profiling: Networking, protein style
Standfirst
Combining protein-network data with gene-expression data may improve the prediction of metastasis formation in patients with breast cancer.
Nature Reviews Cancer 7, 892 - 893 (2007)doi:10.1038/nrc2277
Tumour microenvironment: Inside moving out
Standfirst
Activated fibroblasts found in solid tumours originate from endothelial cells that have undergone endothelial-to-mesenchymal transition (EndMT), raising the question of the extent to which EndMT contributes to tumour progression.
Nature Reviews Cancer 7, 897 (2007)doi:10.1038/nrc2284
Gene expression: Proteins in profile
Standfirst
A new profiling method that maps the quantitative trait loci that control protein levels and compares them to those that affect transcript abundance has enabled the correlation between transcription and protein abundance.
Nature Reviews Genetics 8, 906 - 907 (2007)doi:10.1038/nrg2274
Development: Dancing the polonaise
Standfirst
Visualising individual cell movements has revealed a previously unknown cell intercalation event during gastrulation, where the primitive streak forms at later stage of embryonic development.
Nature Reviews Molecular Cell Biology 8, 946 (2007)doi:10.1038/nrm2305
