Featured Articles
Each month we showcase exciting new cell migration articles from the literature. Access to featured primary research articles from journals in the Nature family is free for three months.
December 2007
Collective cell invasion: Following the leader's tracks
Standfirst
Stromal fibroblasts lead collective cell invasion by deforming the extracellular matrix, thus creating channels that are exploited by the carcinoma cells that follow behind.
Original research paper: Nat. Cell Biol. 9, 1392-1400 (2007)
Lamellipodium, lamella and cofilin: Keeping control of protrusion efficiency
Standfirst
Pak1-mediated activation of cofilin negatively regulates cell protrusion by increasing actin polymerization, enhancing the actin retrograde flow of the lamellipodium, and inducing the spatial reorganization of lamellipodium and lamella.
Original research paper: Dev. Cell 13, 646-662 (2007)