Research Highlights
Short, accessible highlights that summarize and put into context must-read papers related to cell migration.
October 2007
Anticancer drugs: Forecasting drug responses
Standfirst
The US National Cancer Institute has created a database for the in vitro effects of 100,000 anti-cancer compounds on human cancer cell lines, in the hope that it may help in predicting patient drug responses.
Nature Reviews Drug Discovery 6, 782 - 783 (2007)doi:10.1038/nrd2429
Cancer stem cells: Underground movement
Standfirst
Pancreatic cancer aggressiveness may be caused by a combination of two cancer stem cell populations - one for primary tumour growth and the other for metastatic growth.
Nature Reviews Cancer 7, 812 - 813 (2007)doi:10.1038/nrc2257
Tumorigenesis: A shocking enabler of tumour growth
Standfirst
The transcription factor heat-shock factor 1 is crucial to protect against some diseases of ageing, and has now been implicated in the promotion of tumorigenesis.
Nature Reviews Cancer 7, 817 (2007)doi:10.1038/nrc2262
Cancer genetics: Networks uncover new cancer susceptibility suspect
Standfirst
The construction of a breast cancer susceptibility network model has helped identify the hyaluronan-mediated motility receptor as a new susceptibility locus for the disease.
Nature Reviews Genetics 8, 823 (2007)doi:10.1038/nrg2229
