Featured Articles
Each month we showcase exciting new cell migration articles from the literature.
November 2007
RAB25 and alpha5beta1 integrin: Invasion of the pseudopods
Standfirst
RAB25 promotes invasive migration through 3D fibronectin-rich matrices by directly interacting with
5
1 integrin to regulate its recycling at pseudopodial tips.Original research paper: Dev. Cell 13, 496-510 (2007)
Cancer metastasis: A Twist in the microRNA tale
Standfirst
The Twist-induced microRNA miR-10b directly inhibits HOXD10 expression, resulting in RHOC activation and the promotion of tumour invasion and metastasis.
Original research paper: Nature 449, 682-688 (2007)