Research Highlights
Short, accessible highlights that summarize and put into context must-read papers related to cell migration.
October 2007
Breast cancer: On the origins of tumour subtypes
Standfirst
Distinct phenotypes seen in breast epithelial tumours can be attributed in part to different epithelial cells of origin.
Nature Reviews Cancer 7, 726 - 727 (2007)doi:10.1038/nrc2234
Angiogenesis: Inside or outside?
Standfirst
Therapies against tumour angiogenesis that target vascular endothelial growth (VEGF) from the outside of the cell might have less toxicity than those that target it from the inside.
Nature Reviews Cancer 7, 728 (2007)doi:10.1038/nrc2235
Cancer: On the move
Standfirst
The neurotrophin receptor p75 - known to function in axonal outgrowth, neuronal survival and cell death - has now also been implicated in brain tumours as a likely mediator of glioma cell invasion.
Nature Reviews Neuroscience 8, 738 (2007)doi:10.1038/nrn2245
Development: It's not just a gap
Standfirst
The gap junction proteins connexin-26 and -43 control neural migration through their effects on adhesion.
Nature Reviews Molecular Cell Biology 8, 758 - 759 (2007)doi:10.1038/nrm2268
