Research Highlights
Short, accessible highlights that summarize and put into context must-read papers related to cell migration.
August 2007
A useful combination
Standfirst
Combined genomic and functional analyses have led to the isolation of a new breast cancer oncogene, the inhibitor of kB kinase E (IKBKE), thus establishing a link between the NFkB pathway and breast tumours.
Nature Reviews Cancer 7, 570 - 571 (2007)doi:10.1038/nrc2197
Genetic screens: Cell-shape networks get a screening
Standfirst
Descriptions of local signalling networks that regulate cell protrusion, adhesion and tension have enabled the development of new quantitative morphological profiling methods.
Nature Reviews Genetics 8, 570 (2007)doi:10.1038/nrg2168
It's a wrap
Standfirst
Rac1 activity, which is regulated by B1 integrin signalling, is crucial for normal lamellipodial extension in Schwann cells and, therefore, for radial axon sorting.
Nature Reviews Neuroscience 8, 572 - 573 (2007)doi:10.1038/nrn2197
The power of NetworKIN
Standfirst
A new integrative computational approach -NetworKIN- predicts which protein kinases may target experimentally identified phosphorylation sites.
Nature Reviews Molecular Cell Biology 8, 598 - 599 (2007)doi:10.1038/nrm2224
