Featured Articles
Each month we showcase exciting new cell migration articles from the literature.
August 2007
p53 and RhoA signalling: A round about way for tumour invasion
Standfirst
Knocking out the tumour suppressor p53 causes cells to shift from an elongated to a rounded morphology, which is associated with increased motility and tumour invasiveness.
Original research paper: J. Cell Biol. 178, 23-30
From adhesion to migration: The tensin switch
Standfirst
Epidermal growth factor receptor (EGFR) activation induces a switch in expression from tensin-3 to cten, which causes actin stress fibres to dissociate from integrin and disintegrate, thus promoting cell migration.
Original research paper: Nat. Cell. Biol. 9, 961-969