Featured Articles
Each month we showcase exciting new cell migration articles from the literature. Access to featured primary research articles from journals in the Nature family is free for three months.
April 2007
4 integrin-dependent migration: PKA marches at the frontStandfirst
Results showing that
4 integrins anchor type I-cAMP-dependent protein kinases (PKAs) to the leading edge of the migrating cell reveal a new role for type I PKA in cell migration processes.Original research paper: Nature Cell Biology 9, 415-421 (2007)
Directional cell motility: PIP3 Akts via PDK1
Standfirst
Phosphoinositide-dependent kinase-1 (PDK1) activates AKT/PKB by docking to phosphatidylinositol 3,4,5-trisphosphate (PIP3) during cell migration.
Original research paper: Journal Cell Biology 176, 1035-1047 (2007)