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Featured Articles

Each month we showcase exciting new cell migration articles from the literature.

  • April 2007

    alpha4 integrin-dependent migration: PKA marches at the front

    Results showing that alpha4 integrins anchor type I-cAMP-dependent protein kinases (PKAs) to the leading edge of the migrating cell reveal a new role for type I PKA in cell migration processes.

    Mirko von Elstermann Original research paper: Nature Cell Biology 9, 415-421 (2007)

    Directional cell motility: PIP3 Akts via PDK1

    Phosphoinositide-dependent kinase-1 (PDK1) activates AKT/PKB by docking to phosphatidylinositol 3,4,5-trisphosphate (PIP3) during cell migration.

    Mirko von Elstermann Original research paper: Journal Cell Biology 176, 1035-1047 (2007)

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