Featured Articles
Each month we showcase exciting new cell migration articles from the literature.
July 2005
Cell adhesion: ADAM10 sheds the brakes
Standfirst
Identification of ADAM10 as a key mediator of E-cadherin proteolytic cleavage and
-catenin translocation provides new insights into the regulation of cell-cell adhesion and migration.Original research paper: PNAS 102, 9182-9187 (2005)
DOCK180 puts Rac in its place
Standfirst
Through a newly identified PtdIns(3,4,5)P3-binding domain, DOCK180 can target Rac to the leading edge of migrating cells.
Original research paper: Nature Cell Biology 7, 797-807 (2005)