Featured Articles
Each month we showcase exciting new cell migration articles from the literature.
June 2005
Adhesion disassembly: a dynamin disappearing act
Standfirst
Gregg Gundersen and colleagues report the development of a new model system for watching adhesion disassembly, and reveal that a distinct pathway is used compared with assembly — one that requires dynamin.
Original research paper: Nature Cell Biol 7, 581-590 (2005)
A move in the right direction
Standfirst
mRNAs encoding the individual components of the Arp2/3 complex, important for actin nucleation, are targeted to protrusions at the leading edge of migrating cells, and thereby provide an efficient means to generate this key complex locally.
Original research paper: J. Cell Sci. 118, 2425-2433 (2005)